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Manmeet Soni

Lead Independent Director at PULSE BIOSCIENCES
Board

About Manmeet S. Soni

Independent director and Lead Independent Director of Pulse Biosciences (PLSE) since March 2023; director since November 2017. Age 47 as of December 31, 2024. Finance executive in life sciences with CPA (U.S.) and Chartered Accountant (India) credentials; designated Audit Committee financial expert. Currently Chief Operating Officer of Summit Therapeutics and previously CFO/COO roles at Reata, Alnylam, ARIAD, and Pharmacyclics, with prior experience at PwC and Zeltiq Aesthetics .

Past Roles

OrganizationRoleTenureCommittees/Impact
Reata PharmaceuticalsCFO (EVP) → COO & CFO (EVP)Aug 2019–Jun 2020 (CFO); Jun 2020–Aug 2019 then through 2020 as COO & CFO; continued until Aug 2019 stated, promoted in Jun 2020Led finance and operations for small-molecule therapeutics; transition through acquisition contexts
Alnylam PharmaceuticalsSVP & CFOMay 2017–Aug 2019Public biotech CFO; capital markets and reporting
ARIAD PharmaceuticalsEVP, CFO & TreasurerMar 2016–Feb 2017 (continued with Takeda thru May 2017)Managed sale to Takeda; post-acquisition transition support
PharmacyclicsCFO; post-merger transition supportUntil May 2015 (support to Sept 2015)Oncology biotech CFO; acquisition by AbbVie
Zeltiq AestheticsCorporate ControllerPrior to PharmacyclicsMedical device controller role
PwC (U.S./India)Life sciences & venture capital group; Audit/AssuranceEarly careerAudit, assurance, technical accounting

External Roles

OrganizationRoleTenureNotes
Summit Therapeutics Inc.COO; DirectorCOO since Oct 2023; Director since Dec 2019Summit is controlled by PLSE co‑Chair Robert W. Duggan (majority stockholder); Zanganeh is co‑CEO—board interlocks with PLSE
Arena Pharmaceuticals, Inc.DirectorDec 2018–Jun 2021Public company board service

Board Governance

  • Lead Independent Director (appointed March 2023), serves as liaison for independent directors and leads executive sessions .
  • Committee leadership:
    • Audit Committee: Chair; committee met 8 times in 2024. Designated financial expert; current two‑member composition is non‑compliant with Nasdaq Rule 5605(c)(2)(A) and within cure period (governance risk) .
    • Compensation Committee: Chair; met 1 time in 2024 .
    • Nominating & Corporate Governance Committee: Chair; met 1 time in 2024 .
    • Strategic Advisory Committee: Member; met 9 times in 2024 .
  • Attendance: Board held 5 meetings in 2024; each director attended at least 75% of Board and applicable committee meetings; all current Board members attended the 2024 annual meeting .
  • Independence: Board determined Soni is independent under Nasdaq and SEC rules; all committee compositions where he serves meet independence standards .

Fixed Compensation

ComponentAmount/PolicyNotes
Annual Board retainer$55,000Amended Aug 2024
Committee membership retainersStrategic Advisory: $75,000; Audit: $13,000; Compensation: $7,500; Nominating & Governance: $5,500Non‑chair members
Committee chair retainersAudit Chair: $26,000; Compensation Chair: $15,300; Nominating & Governance Chair: $11,000Chair roles
Lead Independent Director retainer$80,000Added Mar 2023
2024 cash fees earned (Soni)$190,115Reflects partial year and amended policy installments

Performance Compensation

Equity ComponentGrant MechanicsVestingChange‑in‑Control Treatment
New director initial option50,000 options1/3 at 1‑yr; remainder monthly over next 2 yrsFull vest at 100% target; restrictions lapse upon change in control (single trigger)
Strategic Advisory Committee initial option200,000 options1/4 at next annual meeting; remainder monthly over 3 yrsSame as above; LaViolette’s SAC grant amended to continue vest ex officio; SAC grants for Soni ratified Sep 30, 2025
Annual director option20,000 options at annual meetingMonthly over 1 yearSame as above
Retainer Option ElectionOption value equals 3x foregone cash retainer divided by FMV on grant dateDirector may convert all/part of cash retainer to optionsStandard plan terms
2024 option awards (Soni)$2,662,186 grant‑date fair valueReflect equity‑heavy compensation mixValued under ASC 718

Other Directorships & Interlocks

LinkageDetailImplication
Summit TherapeuticsSoni COO and director; Duggan is Summit co‑CEO and majority stockholder; Zanganeh co‑CEOInformation flow and influence across PLSE and Summit; potential perceived conflicts given Duggan’s 72.1% stake in PLSE
Family relationship on PLSE boardDuggan and Zanganeh married Dec 2024Heightened related‑party sensitivity (though not directly involving Soni)

Expertise & Qualifications

  • Audit Committee financial expert; meets Nasdaq/SEC financial literacy requirements .
  • CPA (U.S.) and Chartered Accountant (India); extensive life sciences finance and operations leadership .
  • Prior public company board experience (Arena; Summit) and transaction execution across multiple biopharma platforms .

Equity Ownership

MetricValueNotes
Total beneficial ownership413,885 sharesRepresents shares exercisable within 60 days (options/warrants); less than 1% of class as of Oct 22, 2025
Shares owned directlyNo direct share ownership disclosed as of Oct 22, 2025
Rights to acquire within 60 days413,885Exercisable options/warrants
Options outstanding (12/31/2024)528,885Aggregate options outstanding
Options exercisable (12/31/2024)318,885Aggregate options exercisable
Pledging/HedgingNot disclosedNo pledging disclosures identified; company has insider trading policy

Insider Trades

FilingFiled DateUnderlying EventTransaction
Form 4Jun 24, 2024Option grant dated Jun 6, 2024Reporting acquisition of stock options
Form 4Jul 9, 2024Rights offering participation dated Jul 3, 2024Reporting acquisition of PLSE warrants

Governance Assessment

  • Positives
    • Strong independence designations; Lead Independent Director role centralizes independent oversight .
    • Chairs Audit, Compensation, and Nominating/Governance; brings deep finance expertise as Audit Committee financial expert .
    • Clear director compensation policy with transparent retainers and election to convert cash to options; presence of Dodd‑Frank compliant clawback policy for incentive compensation (applies to covered individuals, including NEOs) .
  • Risks and RED FLAGS
    • Audit Committee non‑compliance with Nasdaq’s three‑member requirement since Jan 9, 2025; within cure period but presents risk of potential delisting action if not remedied timely .
    • Significant board interlocks with Summit Therapeutics (Soni COO/director; Duggan majority owner/co‑CEO; Zanganeh co‑CEO) and Duggan’s 72.1% ownership of PLSE could create perceived conflicts and influence over compensation and nominations (Soni chairs both committees) despite independence determinations .
    • Director equity awards feature single‑trigger full acceleration on change‑in‑control (less shareholder friendly relative to double‑trigger norms) .
  • Alignment Indicators
    • Material equity‑based compensation and sizeable outstanding/exercisable option position align Soni with long‑term equity performance, though heavy option mix vs cash raises dilution sensitivity for minority holders .

Overall, Soni’s governance footprint is strong on expertise and engagement, but investor confidence may hinge on swift restoration of Audit Committee compliance and transparent management of interlocks and majority‑owner influence across PLSE and Summit .