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Eugene Williams

Chairman of the Board at ProMIS Neurosciences
Board

About Eugene Williams

Eugene Williams (age 65) is Chairman of the Board at ProMIS Neurosciences, serving as director since June 29, 2015; he was Chairman & CEO from Oct 2021–Sep 2022 and has served as Chairman since Sep 2022. He holds an AB in Economics from Harvard College and an MBA from Harvard Business School, with prior senior executive experience at Genzyme in drug development, commercialization, and licensing .

Past Roles

OrganizationRoleTenureCommittees/Impact
ProMIS NeurosciencesChairman & CEOOct 2021–Sep 2022Led transition; now Chairman since Sep 2022
ProMIS NeurosciencesChairman (non-exec)Jul 2015–Oct 2021Board leadership
Akashi (f/k/a DART Therapeutics)Chairman & CEOJun 2010–Jan 2014Built rare disease platform
GenzymeSenior ExecutivePrior to 2010 (years not specified)Drug development, commercialization, licensing

External Roles

OrganizationRoleStartNotes
Autoimmunity BioSolutions (ABS)Chief Executive OfficerNov 2024Preclinical biotech in autoimmune disease
Acta PharmaceuticalsSVP, StrategyNov 2022Small-molecule therapies and supplements in Alzheimer’s

Board Governance

  • Role and independence: Williams is Board Chair. He is not classified as an independent director; independent directors are identified separately (Kirwin, Mandel-Brehm, Shafmaster, Wyman) .
  • Committee assignments: Williams is not listed on Audit, Compensation, or Corporate Governance & Nominating committees .
  • Committee chairs and composition:
    • Audit Committee: William Wyman (Chair), members Wyman, Kirwin, Mandel-Brehm .
    • Compensation Committee: Maggie Shafmaster, William Wyman (members; chair not explicitly specified) .
    • Corporate Governance & Nominating: Mandel-Brehm, Kirwin, Wyman .
  • Lead Independent Director: Maggie (“Maggie”) K. Shafmaster .
  • Attendance and engagement (FY2024):
    • Board meetings held: 6; Williams attended 6 of 6. All directors attended ≥75% of board/committee meetings and attended the 2024 annual and special meetings .

Fixed Compensation

Component2024 Policy/Terms2024 Actual (Williams)
Board annual cash retainer$40,000 for board membership; additional committee chair/member retainers per policy (Audit Chair $15,000; Audit member $7,500; Comp Chair $10,000; Comp member $5,000; Nominating Chair $8,000; Nominating member $4,000) $50,000 cash fees paid in 2024
Consulting agreementStrategic services consulting agreement starting Sep 12, 2022; service counts toward vesting of outstanding Company equity awards; $225,000 per year paid in equal monthly installments for a 3-year term (through Sep 12, 2025) $225,000 cash consulting fees paid in 2024

Notes:

  • Directors who are executive officers receive no additional director fees; Williams is non-executive but serves as paid consultant under a related-party agreement .

Performance Compensation

AwardGrant dateShares/OptionsExercise PriceGrant-Date Fair ValueVesting/Performance
Annual non-employee director optionPolicy: Annual award of 20,000 options at each annual meeting for continuing non-employee directors 20,000 optionsN/AIncluded in 2024 option value belowVests in full on earlier of 1-year anniversary or next annual meeting; time-based, not metric-based
Option award (Form 4)Oct 3, 202440,000 options$1.11N/ANon-employee director grants per policy are time-based; no performance metrics disclosed
Option award (Form 4)Jun 12, 202520,000 options$0.50N/ATime-based vesting per policy; no performance metrics disclosed
2024 option awards (aggregate)2024$34,968 (ASC 718 fair value)Standard director option grant; no performance metrics disclosed

Performance metrics: The proxy discloses no TSR/revenue/EBITDA or ESG performance conditions for director equity; grants vest on time-based schedules (annual or initial/re-stake) .

Acceleration/Change-in-control: At the board’s discretion, non-employee director awards may fully accelerate upon a “Triggering Event” as defined in the plan .

Plan repricing authority: The 2025 Stock Option & Incentive Plan authorizes the Administrator to reduce exercise prices or reprice via cancellation and re-grants (a governance risk if applied to directors/executives) .

Other Directorships & Interlocks

CompanyExchangeRoleNotes
None disclosedThe proxy states remaining current directors (beyond those specifically listed) are not on the board of any other reporting issuer; no public company directorships disclosed for Williams .

Expertise & Qualifications

  • Education: AB in Economics (Harvard College); MBA (Harvard Business School) .
  • Industry/functional: Senior executive at Genzyme (drug development, commercialization, licensing); CEO roles in biotech (Akashi/DART; ABS) .
  • Board tenure: Director since June 29, 2015; Board Chair since Sep 2022 .

Equity Ownership

As-of dateCommon SharesOptions exercisable within 60 daysWarrants exercisable within 60 daysTotal Beneficial Ownership% of Class
Sep 17, 2025159,930 91,321 7,066 258,317 <1%

Additional context (FY2024 table at April 16, 2025): 363,365 total beneficial (includes 196,369 options within 60 days and 7,066 warrants) .

Recent insider filings (Form 4):

Governance Assessment

  • Independence and related-party exposure

    • Not independent: Williams is not designated as an independent director; independent designations are explicitly noted for other directors (Kirwin, Mandel-Brehm, Shafmaster, Wyman) .
    • Paid consulting arrangement: $225,000 per year under the Williams Consulting Agreement (Sep 12, 2022–Sep 12, 2025), with service counting toward vesting of Williams’ outstanding equity awards; 2024 payments totaled $225,000 (related-party transaction overseen under Audit Committee’s related party oversight) . — RED FLAG (potential conflict and independence impairment)
  • Compensation mix and alignment

    • Director cash fees ($50k in 2024) plus option awards (ASC 718 value $34,968) are consistent with policy; however, consulting fees dwarf standard director compensation, creating atypical pay mix for a board chair . — RED FLAG (pay structure/independence optics)
    • No performance metrics disclosed for director equity; grants vest time-based; plan allows award acceleration upon “Triggering Event” .
  • Board structure and oversight

    • Positive: Separate Lead Independent Director (Shafmaster) and active independent committees; Audit chaired by Wyman; Williams does not sit on key committees (reducing conflict risk in committee decision-making) .
    • Attendance: 100% board attendance in 2024; all directors met attendance thresholds and attended 2024 meetings . — Positive signal of engagement
  • Equity ownership and skin-in-the-game

    • Beneficial ownership <1% of shares; as of Sep 17, 2025, holdings include 159,930 common shares plus options/warrants; no pledging/hedging disclosure noted in proxy (company maintains insider trading policy) . — Neutral to modest alignment
  • Plan design risk

    • The 2025 equity plan explicitly permits option/SAR repricing or re-granting by the Administrator, which is generally shareholder-unfriendly without explicit safeguards . — RED FLAG (plan repricing authority)
  • Other directorships/interlocks

    • No current public-company directorships disclosed; reduces risk of time conflicts or interlocks but limits cross-board benchmarking exposure .

Director Compensation (detail)

Metric2024
Fees earned in cash$50,000
Option awards (ASC 718 fair value)$34,968
All other compensation (consulting)$225,000
Total$309,968

Non-employee director compensation policy (in effect Dec 2024): $40,000 board retainer; committee chair/member retainers as specified; initial director option grant 40,000 (3-year vest, 1/4 at grant then monthly), annual option grant 20,000 (vests by next annual meeting); board may grant re-stake awards; awards may fully accelerate upon a Triggering Event .

Other Directorships & Interlocks

DirectorCurrent Public Company BoardsNotes
Eugene WilliamsNone disclosedProxy notes remaining current directors are not on other reporting issuer boards

Equity Ownership (beneficial; breakdown and %)

HolderCommonOptions (≤60d)Warrants (≤60d)Total% of Shares Outstanding
Eugene Williams159,930 91,321 7,066 258,317 <1%

Key Documents and Citations

Overall implications: Williams’ governance profile features strong engagement and biotech leadership but is tempered by a non-independent status and sizable related-party consulting fees that count toward equity vesting, plus plan-level repricing authority—factors that may weigh on investor confidence absent robust committee independence and oversight, which the current committee structure partially mitigates .