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Alex Nemiroff

General Counsel and Corporate Secretary at Praxis Precision Medicines
Executive

About Alex Nemiroff

Alex Nemiroff, J.D., is General Counsel and Corporate Secretary of Praxis Precision Medicines (PRAX), serving since June 2020; he was previously VP of Legal (Jan–Jun 2020). He holds a B.B.A. from the University of Michigan’s Ross School of Business and a J.D. from Northwestern University School of Law; age 46 as of Apr 30, 2025 . Company performance context: Pay-Versus-Performance shows 2024 cumulative TSR index at $9.33 and GAAP Net Income of -$183 million; Praxis states it does not use financial performance measures in setting NEO pay, focusing instead on clinical/R&D and business objectives .

Past Roles

OrganizationRoleYearsStrategic Impact
Praxis Precision MedicinesGeneral Counsel, Corporate SecretaryJun 2020–present Oversees legal, governance, securities compliance
Praxis Precision MedicinesVP LegalJan 2020–Jun 2020 Built in-house legal function
RogCon, Inc. / RogCon U.R., Inc.Co-founder & CEONov 2015–present Neurology-focused cooperation/licensing relationship with Praxis
Greenberg Traurig LLPCommercial & securities litigationn/d Litigation experience
U.S. District Court (S.D. Fla.)Law Clerk to Hon. Paul C. Huckn/d Federal clerkship foundation

External Roles

OrganizationRoleYearsNotes
RogCon, Inc. / RogCon U.R., Inc.Co-founder & CEONov 2015–present Related party; Praxis has agreements with RogCon

Fixed Compensation

Metric202320242025
Base Salary ($)400,000 442,940 456,228
Target Bonus (%)40% 40% 40%
Actual Bonus Paid ($)176,000 354,352 n/d
Stock Awards ($)444,132 n/d
Option Awards ($)265,767 2,657,652 n/d
Corporate Bonus Factor110% of target (2023) 200% of target (2024) n/d

Performance Compensation

Incentive TypeGrant DateShares/UnitsExercise/Grant PriceGrant Date Fair Value ($)Vesting
Stock Option1/12/202430,000 43.37 980,850 Company disclosed options were granted within 1 business day of material 8-K filing (402(x) timing). Vesting terms by award (see below)
Stock Option (Award A)1/12/202415,000 ex./15,000 unex. 43.37 n/d50% vested at grant; remaining 50% vests: 25% at 1st anniversary, then 36 monthly installments
Stock Option (Award B)20241,516 ex./27,301 unex. (total 28,817) 56.94 n/dVests 7/48ths on 7/29/2024; remaining monthly over 41 months
RSUs (unvested at YE)As of 12/31/20247,800 n/a600,288 (market value at $76.96) RSUs vest in equal annual installments over four anniversaries

Notes:

  • Company states it does not tie executive compensation “actually paid” to financial performance measures; incentive metrics focus on clinical/R&D and business objectives .
  • Equity grant timing aligned to disclosure cadence; options granted within one day following material 8-K filings in 2024 (Item 402(x)) .

Equity Ownership & Alignment

Metric (as of Apr 28, 2025)Amount
Common shares owned3,943.667
Options exercisable within 60 days49,777
Total beneficial ownership (shares)53,720.667
% of shares outstanding (20,368,909)<1%
Hedging policyOfficers and directors prohibited from hedging/derivatives on Company securities
Pledging disclosureNot disclosed
Ownership guidelinesNot disclosed

Employment Terms

Provision2025 Terms
Employment statusAt-will; General Counsel
Severance (without cause/good reason)Salary continuation: 9 months; earned but unpaid prior-year bonus; prorated current-year bonus based on actual performance; Company-paid COBRA up to 9 months or earlier re-eligibility
Change-of-Control (CoC) window & triggerDouble-trigger if termination occurs within 3 months before or 18 months after CoC
CoC cash severanceLump sum: 1.0x (salary + target bonus) plus prorated target bonus; earned but unpaid prior-year bonus
CoC benefitsCOBRA for 12 months; accelerated vesting of 100% of time-based equity; performance-vesting per award terms
280G/4999 exciseCutback to maximize net after-tax benefit (no gross-up)
ClawbackEquity awards subject to clawback/forfeiture per plan/policy and applicable law

Comparative note: Prior summary (2024) disclosed a 12-month CoC window and 1.5x CEO; Nemiroff’s non-CoC severance then did not include prorated bonus; 2025 summary adds prorated bonus and extends CoC window .

Compensation Committee & Governance

  • Compensation Committee: William Young (Chair), Jill DeSimone, Dean Mitchell, Gregory Norden; all independent .
  • Compensation consultant: FW Cook engaged in 2024; Compensation Committee assessed independence and found no conflicts .
  • Annual say-on-pay vote held; Board recommends “FOR” .

Related Party Transactions (Governance Red Flags)

  • RogCon agreements: Praxis advanced up to $1.0M in 2018, later applied to license; cooperation and license agreement entered in 2019; Nemiroff is RogCon co-founder & CEO .

Investment Implications

  • Pay-for-performance alignment: Bonus structure linked to clinical/R&D objectives (not financial metrics); 2024 corporate factor at 200% suggests strong achievement of internal milestones, but investors should map this to external value creation and TSR trends (CAP TSR index low) .
  • Equity-heavy incentives and vesting: Significant 2024 option grants with accelerated schedules (50% vest at grant for one award; front-loaded vesting for another) create potential near/medium-term selling pressure upon vesting and option exercises; monitor Form 4s around monthly vest dates .
  • Retention risk: Standard severance (9 months) and moderate CoC (1x salary+target) terms provide retention balance; extended CoC window (3 months pre/18 post) and full time-based acceleration could influence retention during strategic transactions .
  • Governance caution: Related-party ties to RogCon warrant continued scrutiny of transaction terms and board oversight; hedging prohibition is positive alignment, but pledging policy not disclosed .

Focus catalysts: Equity vesting cadence, any 10b5-1 plans, and upcoming clinical readouts that drive bonus outcomes and option value.

Appendix: Key Company Performance Context (PVP)

Metric2021202220232024
Company TSR (Indexed $100 start)$35.81 $4.33 $2.70 $9.33
Peer Group TSR (SPSIBITR Indexed)$79.62 $59.22 $63.82 $64.57
GAAP Net Income ($mm)-167 -214 -123 -183
Company-selected measureN/A (no financial measures used)

All periods per SEC PVP disclosures.


Sources:

  • Executive biography and roles .
  • Fixed and variable compensation tables and narratives .
  • Equity awards and vesting schedules .
  • Beneficial ownership .
  • Employment terms, severance, and CoC .
  • Compensation committee and consultant .
  • Say-on-pay policy .
  • Hedging policy .
  • Related party transactions (RogCon) .
  • Pay-Versus-Performance metrics .