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Timothy Kelly

Chief Financial Officer at Praxis Precision Medicines
Executive

About Timothy Kelly

Timothy Kelly is Chief Financial Officer of Praxis Precision Medicines and has served as CFO since May 2021; he is 52 years old, with a B.A. in economics from the College of William & Mary and an MBA from Columbia Business School . Prior roles include CFO of Foundation Medicine (2019–Apr 2021) and a series of finance leadership positions at Roche/Genentech (2003–2019) including UK Pharma Finance Director (2017–2019) and Head of Group Strategic Planning (2013–2017) . Praxis’s total shareholder return (TSR) from 12/31/2020 to 12/31/2024 implies a $100 initial investment fell to $9.33, while GAAP net income (loss) for 2024 was -$183 million (values in millions) . Praxis states that it does not use financial performance measures to determine executive pay, focusing instead on clinical/R&D and business objectives .

Past Roles

OrganizationRoleYearsStrategic impact
Foundation Medicine, Inc.Chief Financial Officer2019–Apr 2021Led finance and corporate management functions (accounting/tax, billing/reimbursement, procurement, corp dev, PMO, FP&A) .
Roche Pharma (UK)Finance & Corporate Services Director2017–2019Country finance leadership and corporate services oversight .
Roche Group (Switzerland)Head of Group Strategic Planning2013–2017Group-level strategic planning leadership .
Roche/GenentechVarious finance roles2003–2013Progressive finance responsibilities across Roche and Genentech .

Fixed Compensation

Metric202320242025 (effective Jan 1, where applicable)
Base salary ($)465,000 511,500 526,845
Target annual bonus (% of base)40% 40% 40%
Actual annual bonus ($)204,600 409,200

Notes:

  • 2024 corporate performance was certified at 200% of target; bonuses also incorporate individual performance objectives .
  • Praxis focuses incentive objectives on financial/compliance milestones, portfolio advancement and clinical/R&D goals rather than financial KPIs .

Performance Compensation

Annual cash incentive structure and outcomes:

YearMetric frameworkCorporate performance factorIndividual performanceActual payout ($)Vesting/timing
2024Financial/compliance, CNS portfolio, genetics-informed pipeline, company transformation; plus role-based objectives 200% of target Incorporated (not quantified) 409,200 Paid after year-end per program
2023Financial/compliance, CNS portfolio, genetics-informed pipeline, company transformation; plus role-based objectives 110% of target Incorporated (not quantified) 204,600 Paid after year-end per program

Equity awards are the primary long-term incentive; Praxis uses stock options and RSUs, with vesting designed to promote retention and alignment .

Equity Ownership & Alignment

Beneficial ownership and outstanding awards:

ItemDetail
Beneficial ownership (as of Apr 28, 2025)66,403 shares (<1% of SO), consisting of 3,745 shares plus 62,658 options exercisable within 60 days .
Shares outstanding reference20,368,909 shares of common stock outstanding as of Apr 28, 2025 .
Hedging/derivatives policyOfficers and directors are prohibited from hedging or derivative transactions in Company securities (e.g., options, collars, forwards, swaps, exchange funds) .
PledgingNo explicit pledging prohibition disclosed in the proxy; not disclosed .
Ownership guidelinesNo executive stock ownership guidelines disclosed; not disclosed .

Key outstanding equity awards at 12/31/2024 (selected CFO holdings):

Grant/vesting commencement dateInstrumentExercisableUnexercisableExercise priceExpirationNotes
01/12/2024Stock option15,00015,000$43.3701/12/203450% vested at grant; balance: 25% after 1 year, then monthly over 36 months .
01/12/2024Stock option9,09927,301$56.9407/29/20347/48ths vested on 07/29/2024; remainder monthly over ~41 months .
01/07/2022Stock option4,0741,525$271.6501/07/2032Standard 4-year vesting (25% after 1 year, then monthly) .
06/22/2022Stock option2,7051,628$31.8006/22/2032Standard 4-year vesting .
01/12/2023Stock option (in lieu of prior cash bonus)2,830$44.4001/12/2033Fully vested at grant .
01/12/2023Stock option4,7885,211$44.4001/12/2033Standard vesting .
05/25/2021Stock option11,9331,399$296.1006/01/2031Standard vesting .
01/07/2022RSU800 unvestedRSUs vest in four equal annual installments .
01/12/2024RSU7,800 unvestedRSUs vest in four equal annual installments; value at 12/31/2024: $600,288 at $76.96/share .

Additional alignment and governance items:

  • As of 12/31/2024, the Company’s stock price was $76.96 (used by the Company to value RSUs), implying the 2024 option grants at $43.37 and $56.94 were in-the-money at that date .
  • Equity award timing: in 2024, grants were made within one business day following the filing/furnishing of a Form 8-K disclosing material information; CFO received 30,000 options at $43.37 on 1/12/2024; closing price change the next trading day was -5.38% (Item 402(x) disclosure) .

Employment Terms

TermDetail
Employment statusAt-will .
Base salary (2025)$526,845 .
Target bonus40% of base salary .
Severance (non‑CoC)If terminated without cause or resign for good reason: 9 months base salary continuation; prior-year unpaid bonus if earned; pro‑rated current-year bonus based on actual performance; COBRA premium contribution up to 9 months (conditions apply) .
Change-in-control (double-trigger)If terminated without cause or resign for good reason within 3 months before or 18 months after a CoC: lump sum = 1x (base salary + target bonus) plus pro‑rated target bonus; prior-year unpaid bonus if earned; COBRA premium contribution up to 12 months; 100% acceleration of all time‑based equity; performance-based awards per award terms .
280G treatmentCutback to avoid excise tax if it increases net after-tax benefit; no excise tax gross‑up .
Clawback policyAwards subject to recoupment under Company clawback policy and applicable law, including restatements or errors .
Repricing prohibitionNo option/SAR repricing or cash exchange without stockholder approval (outside limited corporate actions) .
Insider trading/hedgingOfficers/directors prohibited from hedging and derivative transactions in Company securities .

Compensation Structure Analysis

  • Cash vs equity mix: 2024 total comp rose to $4.05M from $1.02M in 2023, driven by a large increase in option awards ($2.66M) and the addition of RSUs ($444k), signaling a shift toward a mixed equity package (options + RSUs) versus 2023’s options-only approach .
  • Bonus outcomes vs goals: Corporate performance was scored at 200% in 2024 vs 110% in 2023, reflecting stronger achievement of disclosed non-financial objectives; Kelly’s bonuses increased accordingly ($409k vs $205k) .
  • Award timing controls: 2024 grants were made immediately after material disclosures (Item 402(x) table), reducing spring-loading concerns .
  • Governance and clawbacks: Plan embeds clawback/recoupment and prohibits repricing without stockholder approval, reducing shareholder risk .

Performance & Track Record

Performance indicator2021202220232024
TSR value of $100 initial investment35.81 4.33 2.70 9.33
GAAP Net Income (Loss), $mm-167 -214 -123 -183

Notes:

  • Praxis discloses that it does not use financial performance measures to set executive compensation; metrics emphasize clinical/R&D and business milestones .
  • 2025 proxy also notes Essential3 interim futility recommendation for ulixacaltamide Study 1; Company is completing both Phase 3 studies with readouts expected in Q3 2025, while advancing epilepsy programs—context for operational risk during Kelly’s tenure as CFO .

Related Party, Perquisites, and Other Considerations

  • Perquisites: “All Other Compensation” for 2024 includes cell phone reimbursement, tax gross-ups on taxable long-term disability and wellness benefits, and Company 401(k) matching contributions .
  • Related party transactions: Policy requires Audit Committee approval for related party deals; no CFO-specific related transactions disclosed .

Investment Implications

  • Alignment and retention: Significant unvested options and RSUs with long-dated, monthly vesting schedules (notably the 2024 grants) support retention and alignment with shareholders; double-trigger CoC protection (1x cash + full time-based equity acceleration) is standard and suggests moderate retention risk absent a transaction .
  • Incentive risk: The Company’s reliance on non-financial metrics (clinical/R&D milestones) and history of high corporate performance factors (200% in 2024) increase discretion and could decouple pay from TSR, which has been weak over the multi-year period .
  • Selling pressure watchpoints: Annual RSU vesting (7,800 units from 2024 award) and ongoing monthly option vesting create potential periodic liquidity events; no hedging allowed, but absence of explicit pledging prohibitions is a governance watch item .
  • Governance strengths: Clawback and anti-repricing provisions, plus disciplined award timing around disclosures, mitigate several pay-risk concerns .