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Bryant Lim

Chief Financial Officer, Chief Legal Officer, and Corporate Secretary at Prelude Therapeutics
Executive

About Bryant Lim

Bryant D. Lim, J.D., is Prelude Therapeutics’ Chief Legal Officer and Corporate Secretary (since Feb 20, 2023), served as Interim CFO (Apr 10, 2024–Feb 3, 2025), and was appointed permanent CFO on Feb 3, 2025 . He is 54 years old (as of Apr 16, 2025), holds a J.D. from Villanova University School of Law and a B.A. from the University of Rochester, and has extensive legal, compliance, governance, and business development experience in biopharma . Company performance context during his tenure: FY2024 revenue was $7.0 million , and EBITDA remained negative at -$137.9 million* (FY2024), -$131.1 million* (FY2023), and -$122.2 million* (FY2022); TSR is not provided in this report due to unavailable market data. Values marked with * are from S&P Global.

Past Roles

OrganizationRoleYearsStrategic Impact
Aceragen Inc.SVP, General Counsel, Chief Business OfficerSep 2022–Feb 2023Led legal, governance, and business development functions
Idera PharmaceuticalsSVP, General Counsel, Chief Business OfficerSep 2018–Oct 2022Instituted and oversaw legal, corporate governance, and BD activities
Incyte CorporationVP, Legal and Global Chief Compliance OfficerMay 2014–Sep 2018Built global compliance; senior legal leadership in large-cap biotech
ViroPharma IncorporatedLegal roles of increasing responsibilityNot disclosedContributed to legal and corporate governance in specialty pharma
Merck & Co., Inc.Legal rolesNot disclosedSupported legal frameworks at large global pharma
Morgan, Lewis & Bockius LLPAttorneyNot disclosedEarly career at leading law firm; federal judicial clerkship

External Roles

OrganizationRoleYearsNotes
Life Sciences PennsylvaniaBoard of DirectorsSince May 2019Statewide biotech industry association

Fixed Compensation

Metric202320242025 Policy
Base Salary ($)$359,282 $444,167 $483,000 (policy)
Target Bonus (%)40% 40% 40%
Actual Bonus Paid (Non-Equity Incentive) ($)$159,083 $166,500 Not disclosed

Performance Compensation

Category20232024
Non-Equity Incentive Payout ($)$159,083 $166,500
Corporate Performance Metrics Tied to Annual BonusCompletion of dose escalation for PRT1419; objective responses to PRT2527; IND studies for PRT3645 and PRT3789; compliance with budget and culture; strengthening corporate functions Completion of dose escalation for PRT2527; IND studies for PRT7732; increased enrollment for PRT3789; confirming ADC lead candidate(s); compliance with budget and culture; strengthening corporate functions
Weightings / Targets / Payout FormulaNot disclosed Not disclosed
Vesting (cash bonus)N/AN/A

Equity Ownership & Alignment

MetricMar 31, 2024Mar 31, 2025
Beneficial Ownership (Voting Common Shares)75,316 212,816
% of Voting Shares OutstandingLess than 1% Less than 1%
Options Exercisable within 60 Days (#)72,916 185,416
Shares Pledged as CollateralNot disclosedNot disclosed

Outstanding Option Awards (as of Dec 31, 2024):

Grant DateExercisable (#)Unexercisable (#)Exercise Price ($)Expiration DateVesting Schedule
3/1/2023109,375 140,625 5.93 2/28/2033 25% at 1-year anniversary, then 1/48 monthly; subject to acceleration on qualifying termination
3/1/2024150,000 4.59 2/28/2034 Same as above
5/14/202425,000 3.86 5/13/2034 Same as above

Policies:

  • Anti-hedging: Executives prohibited from hedging/monetization transactions (e.g., zero-cost collars, forward sales, exchange funds) .
  • Clawback: SEC Rule 10D‑1 compliant policy adopted Sept 2023; 3-year recovery period on restatements .
  • Ownership guidelines: Not disclosed.

Employment Terms

TermDetails
Employment StatusAt-will employment per executive offer letters
Current RolesChief Legal Officer & Corporate Secretary (since Feb 20, 2023); Interim CFO (Apr 10, 2024–Feb 3, 2025); CFO (since Feb 3, 2025)
Base Salary & Target Bonus2025: $483,000 base; 40% target bonus . 2024 plan terms: $415,000 base; 40% target bonus
Non-Compete & Non-SolicitSeverance conditioned on compliance with proprietary information and restrictive covenant agreement (non-compete/non-solicit)
Clawback & Insider TradingClawback per SEC 10D‑1; anti-hedging policy

Severance and Change-in-Control Economics (Named Executive Officer terms):

ItemOrdinary Termination (No Cause)Change-in-Control (Double Trigger)
Salary Continuation9 months 12 months
COBRA/BenefitsCompany-paid/reimbursed during salary period Company-paid/reimbursed during salary period
Bonus TreatmentNot specified100% of annual target bonus multiple
Equity AwardsPartial acceleration for specified awards (CEO/CMO; Lim’s details not separately specified) Full acceleration and exercisability of equity awards
280G/4999 Tax TreatmentBest-net or cutback to avoid excise tax, whichever yields greater after-tax benefit

Company Performance Context (for Pay-for-Performance)

MetricFY 2022FY 2023FY 2024
Revenues ($)7,000,000
EBITDA ($)-122,216,000*-131,108,000*-137,942,000*
Values marked with * are from S&P Global.

Investment Implications

  • Alignment: Lim’s direct/option-based beneficial ownership is less than 1% of outstanding voting shares, indicating limited “skin-in-the-game” relative to float; however, ongoing option grants (2023–2024) and senior roles align his incentives with enterprise value creation .
  • Retention/Change-in-Control: Double-trigger CIC protections (12 months salary, 100% target bonus, full equity acceleration) and ordinary severance (9 months) reduce flight risk in strategic scenarios while potentially increasing cost of leadership transition; tax cutback/best-net provisions avoid gross-ups .
  • Compensation Mix Trends: 2024 option grant value declined ($581,895) versus 2023 ($1,086,904), while cash elements rose modestly, suggesting a shift to more balanced cash/equity mix amid interim-to-permanent CFO transition .
  • Trading Signals: Option grants from 2024 begin vesting at one-year anniversaries per standard 25%/monthly schedules, which can coincide with periodic Form 4 activity; anti-hedging policy mitigates alignment concerns. Form 4 transaction data could not be retrieved in this session; monitor insider filings around vest dates .
  • Performance Metrics Linkage: Annual bonuses tied to discrete R&D milestones (dose escalation, INDs, enrollment, ADC candidate selection) and operational discipline; weightings/targets were not disclosed, but payouts were modest ($159k in 2023; $166k in 2024), indicating measured variable pay tied to execution .

Overall: Compensation terms and CIC protections suggest stable retention in a clinically driven biotech. Equity award cadence provides alignment, albeit with a small ownership base. Focus areas for investors are milestone execution (which drives cash bonuses), option vesting calendars for potential insider activity, and any updates to ownership guidelines or pledging policies.