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Julian Baker

Director at Prelude Therapeutics
Board

About Julian C. Baker

Julian C. Baker (age 57 as of April 18, 2024) is an independent Class II director of Prelude Therapeutics since January 2021; he is a Managing Member of Baker Bros. Advisors LP and holds an A.B. from Harvard University . He brings over three decades of biotech investment experience and serves on multiple public company boards, including chair roles, providing finance, capital markets, and governance expertise .

Past Roles

OrganizationRoleTenureCommittees/Impact
Tisch Financial ManagementPortfolio Manager1994–1999Public markets investing in healthcare
Credit Suisse First Boston (Private Equity)Investment professional1988–1993Private equity investing

External Roles

OrganizationRoleTenureNotes
Baker Bros. Advisors LPManaging Member2000–presentCo-founded with Felix Baker; biotech-focused investment adviser
Madrigal Pharmaceuticals (MDGL)Director; ChairmanCurrentChairman; PRLD Chair Paul A. Friedman also serves on MDGL board, creating a board interlock
Incyte Corporation (INCY)DirectorCurrentPublic company directorship
Acadia Pharmaceuticals (ACAD)DirectorCurrentPublic company directorship
Denali Therapeutics (DNLI)Director; Chair of the BoardCurrentChair of Denali’s board

Board Governance

  • Independence: The Board determined Mr. Baker is an “independent director” under Nasdaq and SEC rules .
  • Committees and Chair roles (2024–2025):
    • Chair, Nominating & Corporate Governance Committee
    • Member, Compensation Committee
  • Attendance and engagement: In 2024, no director attended fewer than 75% of aggregate Board and committee meetings during their tenure; independents meet separately on a regular basis .
  • Board leadership: CEO and Chair roles are separated (CEO: Krishna Vaddi; Chair: Paul A. Friedman) .
  • Anti-hedging: Directors are prohibited from hedging company stock .
  • Clawback: Compensation recovery policy adopted in Sept 2023 (primarily for executive incentive compensation) .

Fixed Compensation

ItemPolicy/AmountNotes
Board retainer (cash)$35,000Non-employee directors
Chair of Board (additional)$30,000If applicable
Committee retainersAudit Chair $15,000; Audit Member $7,500; Comp Chair $10,000; Comp Member $5,000; N&CG Chair $8,000; N&CG Member $4,000Reflects roles; Baker is N&CG Chair and Comp Member
2024 Cash paid to J. Baker$51,159Paid under Director Compensation Policy; paid directly to his employer

Performance Compensation

Award TypeGrant DateShares/UnitsFair ValueVestingPerformance Metrics
Non-employee director annual stock option grant2024-06-14 (date of annual meeting)23,500 optionsSee individual’s 2024 total option award fair value $65,319 (ASC 718)Vests on earlier of next annual meeting or one-year anniversary; service-basedNone (service-vesting only)

Note: 2024 non-employee director annual grant size was 23,500 options; vesting is purely service-based; no revenue/TSR/ESG metrics disclosed .

Other Directorships & Interlocks

  • Public boards: Incyte, Acadia, Madrigal (Chairman), Denali (Chair), Prelude .
  • Interlocks:
    • Madrigal: Both Julian C. Baker (Chairman) and PRLD Chair Paul A. Friedman serve on MDGL’s board .
    • Investor-affiliated directors: Baker (Baker Bros. Advisors LP) and David Bonita (OrbiMed) both serve on PRLD’s board, reflecting significant investor representation .

Expertise & Qualifications

  • Education: A.B., Harvard University .
  • Core expertise: Biotech investing, capital allocation, governance, and compensation oversight; chair experience on public boards .

Equity Ownership

CategoryAmount% of ClassNotes
Voting common stock beneficially owned10,246,46823.4%Aggregated through Baker Funds; see footnotes
Non-voting common stock beneficially owned7,170,07355.8%Convertible to voting only subject to 9.99% “Beneficial Ownership Limitation” (adjustable up to 19.99% on 61-day notice)
Options exercisable within 60 days (Baker)122,644As of March 31, 2025
Pre-funded warrants (Baker Funds)19,532,0154.99% “Maximum Percentage” exercise cap; may be reset up to 19.99% on 61-day notice

Alignment signals: Very large beneficial stake via Baker Funds strongly aligns interests with equity holders; however, concentrated ownership and convertible/warrant structures can amplify investor influence over capital and control dynamics .

Insider Trades (Form 4)

Filing DateNatureSecuritiesNotes/Source
2024-06-18Annual non-employee director option grant23,500 non-qualified stock optionsConfirmed in Form 4; consistent with 2024 annual director grant policy
2025-06-13Director equity transaction reported (Form 4)Notional details in filingForm 4 filed; reflects annual director equity reporting cycle

Related-Party/Conflicts Review

  • Board independence determination: Despite significant shareholdings via Baker Bros. Advisors LP, the Board classified Mr. Baker as independent under Nasdaq/SEC rules .
  • Related party transactions: Company reports no related party transactions >$120,000 from Jan 1, 2024 to proxy filing date, other than director/executive compensation .
  • Capital raises/participation: In May 2023, Baker Funds participated in PRLD’s public offering (non-voting common and pre-funded warrants), and in Dec 2023 PRLD entered into a Securities Purchase Agreement and amended registration rights with Baker Funds (as disclosed in 13D/A and filings) .
  • Director fees remitted to employer: Mr. Baker’s director compensation was paid directly to Baker Bros. Advisors LP .

Governance Assessment

  • Positives:
    • Independent status, committee leadership (Chair, N&CG; Member, Comp), and at least 75% meeting attendance support board effectiveness .
    • Separation of Chair/CEO roles; independent director executive sessions enhance oversight; anti-hedging and clawback policies strengthen governance controls .
    • Use of independent compensation consultant (Compensia) for board and executive comp; mitigates pay-setting conflicts .
  • Watch items / potential red flags:
    • Concentrated ownership and complex instruments (non-voting shares, pre-funded warrants with adjustable caps) could magnify investor influence; continued disclosure and recusal practices are important for conflict management .
    • Interlock at Madrigal (two PRLD directors on same external board) may raise information-flow/overboarding considerations, though no specific conflict is disclosed .
    • Director compensation directed to employer underscores investor-affiliated status; Board nonetheless affirms independence .
  • Current disclosure indicates no material related-party transactions in 2024 beyond standard compensation; prior financing participation by Baker Funds is well-disclosed .

Director Compensation (Detail)

YearFees Earned (Cash)Option Awards (FV)TotalNotes
2024$51,159$65,319$116,478Paid to employer; options vest by next AGM; 23,500 grant policy
2023$48,000$92,034$140,034Paid to employer; 23,500 annual grant policy in 2023

Committee Assignments (Current)

CommitteeRole
Nominating & Corporate GovernanceChair
CompensationMember

Independence, Attendance, Engagement

  • Determined independent by the Board (Nasdaq/SEC standards) .
  • Attendance: Met at least the 75% threshold in 2024 based on company disclosure that no director fell below it; Board met 5x; Comp Committee met 4x; N&CG met 1x in 2024 .
  • Independent directors meet in executive sessions regularly .

Say-on-Pay Context

  • Prelude is an Emerging Growth Company and Smaller Reporting Company; not required to hold say-on-pay votes; reduced compensation disclosure applies .