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Sarah O'Dowd

Director at Protagonist TherapeuticsProtagonist Therapeutics
Board

About Sarah A. O’Dowd

Independent director at Protagonist Therapeutics since August 2020; age 75, with prior senior legal and HR leadership roles at Lam Research and VP roles at FibroGen. Education: J.D., Stanford Law; M.A. Communications, Stanford; A.B. Mathematics, Immaculata College . The Board has affirmatively determined she is independent under Nasdaq standards .

Past Roles

OrganizationRoleTenureCommittees/Impact
Lam Research Corporation (LRCX)Senior Vice President & Chief Legal Officer; Corporate Secretary; Group VP of Human ResourcesCLO/Secretary 11 years; HR 2009–2012; retired March 2020Senior legal executive; human capital leadership at S&P 500 tech firm
FibroGen, Inc. (FGEN)Vice PresidentFeb 2007 – Sep 2008Public-company biotech legal leadership
Heller Ehrman LLPAdvisor; Founded Silicon Valley and San Diego offices; Global business practice group chair1978 – 2007Advised boards and CEOs; led global practice (7 offices, 250+ attorneys)

External Roles

OrganizationRoleTenureCommittees/Impact
Ichor Holdings, Ltd. (ICHR)Director2020 – presentAudit Committee member; Human Capital Committee member; brings semiconductor manufacturing/process and human capital expertise
Independent InstituteDirectorNot statedNon-profit public policy organization director

Board Governance

  • Committee memberships (PTGX): Audit Committee member (effective Sep 19, 2024); Research Committee member .
  • Committee meeting cadence (FY 2024): Audit 5; Compensation 4; Nominating & Corporate Governance 3; Research 4 .
  • Independence and leadership: Independent; Board chaired by independent Chair (Dr. Selick); independent directors meet in executive session at every regular Board meeting .
  • Attendance: Each director attended ≥75% of Board and applicable committee meetings in FY 2024; five directors attended the 2024 Annual Meeting .

Fixed Compensation (PTGX non‑employee director program)

ComponentAmountNotes
Annual Board retainer (non‑chair)$40,000 Paid quarterly; increased to $45,000 effective Jan 1, 2025
Chair of the Board$75,000
Committee Chair retainersAudit $20,000; Compensation $15,000; Nominating $10,000; Research $10,000
Committee member retainers (non‑chair)Audit $10,000; Compensation $7,500; Nominating $5,000; Research $5,000
Sarah O’Dowd actual cash fees (2024)$51,549 Reflects board and committee service in 2024

Performance Compensation (PTGX non‑employee director equity)

Metric2024VestingChange‑in‑Control2025 Changes
Annual option grantOption to purchase 25,700 shares Monthly over 12 months Options vest in full upon change in control Annual equity to be 50% stock options / 50% RSUs; targeted total value $400,000; RSUs vest 100% at first anniversary; options vest per policy
Sarah O’Dowd 2024 option award fair value$471,734 As granted; see vesting aboveStandard director policy applies One‑time 2025 cash retainer reduction to offset 2024 total comp >$500k under plan limits

Performance metric design (board program context)

  • Directors do not have performance cash bonuses; equity is time‑vesting. For executives, PTGX uses corporate R&D, finance, and stretch goals to fund bonuses; not applicable to director compensation .

Other Directorships & Interlocks

CompanyYearFees Earned (Cash)Equity Awards (Value)Total
Ichor Holdings (ICHR)2024$77,500 $150,021 $227,521
Ichor Holdings (ICHR)2023$77,500 $150,021 $227,521
Ichor Holdings (ICHR)2022$72,500 $150,004 $222,504
  • ICHR committee roles: Audit Committee member; Human Capital Committee member .
  • No disclosed related‑party transactions at PTGX since Jan 1, 2024 (mitigates conflict risk) .

Expertise & Qualifications

  • Legal, governance, and human capital leadership in public‑company settings; semiconductor industry/process knowledge via Lam and Ichor .
  • Education: J.D. (Stanford), M.A. Communications (Stanford), A.B. Mathematics (Immaculata) .

Equity Ownership (Alignment at PTGX)

HolderShares Beneficially Owned% OutstandingComposition
Sarah A. O’Dowd125,894 <1% (“*” denotes <1%) Consists entirely of shares issuable upon exercise of stock options exercisable within 60 days
Options outstanding (at 12/31/2024)123,700 Directors did not hold RSUs as of year‑end 2024
  • Insider trading policy: Hedging and pledging of company stock prohibited; robust clawback policy adopted per Nasdaq Rule 5608; double‑trigger equity vesting on change in control for executives; director options vest on change in control per policy .

Governance Assessment

  • Board effectiveness: Independent status; active committee service (Audit, Research); executive sessions each regular meeting; attendance at or above minimum thresholds—favorable governance signals .
  • Compensation mix and alignment: PTGX director pay is predominantly equity via time‑vested options; 2024 grant fair values were elevated (~$472k), prompting a proactive 2025 cash retainer reduction to respect plan limits—responsiveness mitigates pay inflation concerns . 2025 shift to 50/50 options/RSUs aligns directors with multi‑year equity while moderating option risk .
  • Ownership “skin in the game”: Beneficial ownership appears entirely via exercisable options; absence of direct share holdings or RSUs at year‑end may be a modest alignment gap versus guideline‑driven share ownership programs (PTGX does not disclose director ownership guidelines) .
  • Conflicts and related‑party exposure: No related‑party transactions disclosed; service cap limits on outside boards (≤4 public boards) reduce overboarding risk; O’Dowd’s external public board role (ICHR) is in semicap equipment—low direct conflict with biotech operations .
  • Risk indicators: Clawback policy in place; hedging/pledging prohibited; double‑trigger CIC equity for executives; no excise tax gross‑ups—shareholder‑friendly practices .
  • Attendance and engagement: Aggregate disclosure indicates ≥75% attendance; independent directors meet without management each regular meeting; continued monitoring for individual attendance detail advisable .

RED FLAGS

  • 2024 director equity grant values resulted in total compensation above $500k; while mitigated by the 2025 cash reduction, investors should monitor ongoing director pay levels and equity sizing versus peer biotech boards .
  • Ownership alignment relies on options; lack of disclosed direct shareholding or RSUs for O’Dowd at year‑end—consider tracking future RSU adoption under 2025 policy and any direct holdings updates .