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Alexander Arrow

Chief Financial Officer at Protagenic Therapeutics, Inc.\newProtagenic Therapeutics, Inc.\new
Executive

About Alexander Arrow

Alexander K. Arrow, M.D., CFA, is Protagenic Therapeutics’ Chief Financial Officer since February 2016; he is 53 per the company’s FY 2023 Form 10-K executive roster . His credentials include an M.D. from Harvard Medical School (1996), a B.A. in Biophysics from Cornell University (1992, magna cum laude), and the CFA designation (1999) . Biography highlights include leadership roles across medtech and life sciences (CFO and operating executive roles at Arstasis, Carlsmed, Strateos; President/COO and Audit/Comp Committee Chair at Biolase; equity research head at Lazard Capital Markets; board roles at Insightful Instruments, Paragonix Technologies, and Neumedicines) . Pay-versus-performance disclosures show cumulative Total Stockholder Return benchmarks and net losses: TSR value of an initial $100 investment was $38.10 in 2023 and $131.90 in 2022; net losses were $5.0 million in 2023 and $3.56 million in 2022, evidencing alignment commentary around equity-based incentives .

Past Roles

OrganizationRoleYearsStrategic Impact
Lazard Capital MarketsHead of Medical Technology Equity Research2002–2007Led medtech equity research at a global investment bank
Patent & License ExchangeChief Financial Officer1999–2001Finance leadership at IP marketplace
Wedbush Morgan SecuritiesLife Sciences Research Analyst~1996–1999Sell-side coverage in life sciences prior to CFA
Arstasis, Inc.Chief Financial Officer2007–2012Scaled cardiology device manufacturer
Circuit TherapeuticsChief Medical & Strategic OfficerNot disclosedOptogenetics strategy and medical leadership
Biolase, Inc. (NASDAQ: BIOL)President & COO; Director; Audit & Compensation Committee Chair2010–2014Operating turnaround and governance leadership at dental lasers leader

External Roles

OrganizationRoleYearsStrategic Impact
Corramedical, Inc.Chief Executive OfficerCurrentMedical device platform leveraging patient-derived cellular resources
Strateos, Inc.Chief Financial OfficerPreviously/current per filingDrug discovery automation/robotics for pharma
Insightful Instruments, Inc.DirectorCurrentBoard role at novel refractive surgery tool developer
Paragonix TechnologiesDirector (prior)Prior; acquired Sept 2024Supplier of leading organ transport device; acquired by Getinge AB for $469 million
Neumedicines, Inc.Director (prior)PriorProtein therapeutics in Oncology/Hematology/Immunology

Fixed Compensation

Metric202220232024
Base Salary ($)$136,538 $150,000 $150,000
Cash Bonus ($)$0 $0 $0
Stock Awards ($)$0 $0 $0
Option Awards ($)$0 $0 $32,605
Total Compensation ($)$136,538 $150,000 $182,605

Employment arrangements: Arrow serves as a part-time CFO with a base salary of $150,000 (raised from $125,000 on July 1, 2021); from Feb 2019–Aug 2020 he received zero cash salary and three option grants totaling ~88,541 options in lieu of cash compensation .

Performance Compensation

MetricWeightingTargetActualPayoutVesting
Cash incentive (NEIP)Not disclosedNot disclosedNot disclosed$0 in 2022–2024 Not disclosed
RSUs/PSUsNot disclosedNot disclosedNot disclosedNo RSU/PSU disclosedNot disclosed
Stock Options (time-based)Not applicableNot applicableNot applicable$32,605 grant-date value in 2024; $0 in 2023/2022 Company discloses full vesting acceleration upon change of control/resignation for Good Reason/involuntary termination other than For Cause

Equity program commentary (smaller reporting company): disclosures emphasize alignment via equity grants; CAP vs TSR discussion indicates relative alignment but does not set explicit financial/performance metric targets (e.g., revenue/EBITDA/TSR percentiles) for Arrow’s pay .

Equity Ownership & Alignment

  • Beneficial ownership (as of April 1, 2024): Arrow beneficially owned 244,773 shares (including 45,815 common shares and 198,958 options exercisable within 60 days); 98,333 options were not exercisable within 60 days. Percent of class: 5% .
  • Change-of-control acceleration: 100% of then‑unvested options vest upon a qualified change of control, resignation for Good Reason, or involuntary termination other than For Cause .
  • Pledging/hedging: No pledging disclosure found in reviewed proxy/10-K sections .
Ownership DetailAmountNotes
Common shares owned45,815 Direct holdings
Options exercisable ≤60 days198,958 Exercise prices include $1.74, $4.00, $5.00, $7.00
Options not exercisable ≤60 days98,333 Unvested/unexercisable
Beneficial ownership (% of class)5% As of April 1, 2024

Outstanding option grants (Dec 31, 2024):

Grant (Ref)Exercisable (#)Unexercisable (#)Exercise PriceExpiration
(5)25,000 $5.00Feb 12, 2026
(6)35,000 $5.00Apr 15, 2026
(7)18,750 $7.00Oct 16, 2027
(8)10,417 $4.00Feb 1, 2029
(9)30,000 $7.00Feb 13, 2030
(10)46,874 $7.00Feb 13, 2030
(11)31,250 $7.00Jul 18, 2030
(12)25,000 75,000 $1.74Mar 25, 2034

Option repricing event: On Feb 21, 2025, shareholders approved repricing authority; the Board repriced all outstanding option grants under the 2006 and 2016 plans to $0.2655 per share (closing price on Feb 21, 2025). This is a compensation governance red flag (repricing of underwater options) and may alter incentive alignment and near-term selling pressure dynamics .

Employment Terms

  • Base salary and part-time arrangement: $150,000 per year; previously $125,000 until July 1, 2021 .
  • Equity history: cumulative grants include 25,000 options under the 2006 plan and extensive grants under the 2016 plan (exercise prices historically at $1.74, $4.00, $5.00, $7.00) with latest 2034-dated grant at $1.74 (25,000 exercisable; 75,000 unexercisable) .
  • Change-of-control economics: full acceleration of unvested options on qualified change-of-control/resignation for Good Reason/involuntary termination other than For Cause .
  • Severance multiples, non-compete, non-solicit, garden leave, clawback, tax gross-ups, stock ownership guidelines: not disclosed in reviewed filings .

Performance & Track Record

  • Corporate actions and restructuring: Arrow signed multiple 8-Ks reflecting governance and operating changes, including a restructuring pivot to prioritize the Phase 2 clinical trial of PT00114 and elimination of certain executive roles, transitioning to a virtual operating model to minimize burn .
  • Governance signatures: Arrow signed numerous SEC filings and special meeting proxies in his capacity as CFO/Secretary .
  • External value creation: Serving on the board of Paragonix, which was acquired in Sept 2024 by Getinge AB for $469 million, highlighting engagement with value-creating assets in medtech .

Risk Indicators & Red Flags

  • Option repricing (Feb 2025): Repricing all outstanding options to $0.2655 per share is a governance red flag, potentially weakening pay-for-performance rigor and altering equity overhang/selling dynamics .
  • Nasdaq compliance pressures: Proxies discuss reverse split authority to regain compliance with Nasdaq minimum bid and equity requirements, underscoring listing risk context during Arrow’s tenure .

Compensation Structure Analysis

  • Mix shift: 2024 introduced option grant value ($32,605) after no equity value recognized in 2023/2022; overall pay remains heavily fixed (salary) with minimal variable cash incentives .
  • Guaranteed vs at-risk: No cash bonus or PSU programs disclosed; equity is primarily time-based options with change-of-control acceleration; repricing materially reduces strike prices—indicative of reduced performance risk for equity holders .
  • Performance metrics: No explicit revenue/EBITDA/TSR target linkages or weightings disclosed for Arrow’s incentive pay; company’s narrative references alignment via equity grants rather than metric-based plans .

Equity Ownership & Alignment

ItemDetail
Beneficial ownership244,773 shares (45,815 common + 198,958 options exercisable in 60 days); 98,333 options not exercisable within 60 days; 5% of class as of April 1, 2024
Ownership guidelinesNot disclosed
Pledging/HedgingNo pledging disclosure found
In-the-money valueNot calculated here; requires current market price (not in filings)

Investment Implications

  • Pay-for-performance rigor appears limited: No disclosed cash incentive plan metrics and predominantly time-based options with change-of-control acceleration; 2025 option repricing to $0.2655 materially reduces performance hurdle for equity awards—monitor dilution and exercise behavior post-repricing .
  • Retention risk seems moderated by equity mechanics: Extensive vested options and change-of-control acceleration favor retention/alignment in strategic events; part-time CFO compensation structure suggests limited fixed cost burden .
  • Governance and listing risk context: Reverse-split authority and Nasdaq compliance discussions signal elevated capital markets risk; CFO stewardship through restructuring and trial focus should be weighed against historical losses and TSR trajectory .