Alexander Arrow
About Alexander Arrow
Alexander K. Arrow, M.D., CFA, is Protagenic Therapeutics’ Chief Financial Officer since February 2016; he is 53 per the company’s FY 2023 Form 10-K executive roster . His credentials include an M.D. from Harvard Medical School (1996), a B.A. in Biophysics from Cornell University (1992, magna cum laude), and the CFA designation (1999) . Biography highlights include leadership roles across medtech and life sciences (CFO and operating executive roles at Arstasis, Carlsmed, Strateos; President/COO and Audit/Comp Committee Chair at Biolase; equity research head at Lazard Capital Markets; board roles at Insightful Instruments, Paragonix Technologies, and Neumedicines) . Pay-versus-performance disclosures show cumulative Total Stockholder Return benchmarks and net losses: TSR value of an initial $100 investment was $38.10 in 2023 and $131.90 in 2022; net losses were $5.0 million in 2023 and $3.56 million in 2022, evidencing alignment commentary around equity-based incentives .
Past Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Lazard Capital Markets | Head of Medical Technology Equity Research | 2002–2007 | Led medtech equity research at a global investment bank |
| Patent & License Exchange | Chief Financial Officer | 1999–2001 | Finance leadership at IP marketplace |
| Wedbush Morgan Securities | Life Sciences Research Analyst | ~1996–1999 | Sell-side coverage in life sciences prior to CFA |
| Arstasis, Inc. | Chief Financial Officer | 2007–2012 | Scaled cardiology device manufacturer |
| Circuit Therapeutics | Chief Medical & Strategic Officer | Not disclosed | Optogenetics strategy and medical leadership |
| Biolase, Inc. (NASDAQ: BIOL) | President & COO; Director; Audit & Compensation Committee Chair | 2010–2014 | Operating turnaround and governance leadership at dental lasers leader |
External Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Corramedical, Inc. | Chief Executive Officer | Current | Medical device platform leveraging patient-derived cellular resources |
| Strateos, Inc. | Chief Financial Officer | Previously/current per filing | Drug discovery automation/robotics for pharma |
| Insightful Instruments, Inc. | Director | Current | Board role at novel refractive surgery tool developer |
| Paragonix Technologies | Director (prior) | Prior; acquired Sept 2024 | Supplier of leading organ transport device; acquired by Getinge AB for $469 million |
| Neumedicines, Inc. | Director (prior) | Prior | Protein therapeutics in Oncology/Hematology/Immunology |
Fixed Compensation
| Metric | 2022 | 2023 | 2024 |
|---|---|---|---|
| Base Salary ($) | $136,538 | $150,000 | $150,000 |
| Cash Bonus ($) | $0 | $0 | $0 |
| Stock Awards ($) | $0 | $0 | $0 |
| Option Awards ($) | $0 | $0 | $32,605 |
| Total Compensation ($) | $136,538 | $150,000 | $182,605 |
Employment arrangements: Arrow serves as a part-time CFO with a base salary of $150,000 (raised from $125,000 on July 1, 2021); from Feb 2019–Aug 2020 he received zero cash salary and three option grants totaling ~88,541 options in lieu of cash compensation .
Performance Compensation
| Metric | Weighting | Target | Actual | Payout | Vesting |
|---|---|---|---|---|---|
| Cash incentive (NEIP) | Not disclosed | Not disclosed | Not disclosed | $0 in 2022–2024 | Not disclosed |
| RSUs/PSUs | Not disclosed | Not disclosed | Not disclosed | No RSU/PSU disclosed | Not disclosed |
| Stock Options (time-based) | Not applicable | Not applicable | Not applicable | $32,605 grant-date value in 2024; $0 in 2023/2022 | Company discloses full vesting acceleration upon change of control/resignation for Good Reason/involuntary termination other than For Cause |
Equity program commentary (smaller reporting company): disclosures emphasize alignment via equity grants; CAP vs TSR discussion indicates relative alignment but does not set explicit financial/performance metric targets (e.g., revenue/EBITDA/TSR percentiles) for Arrow’s pay .
Equity Ownership & Alignment
- Beneficial ownership (as of April 1, 2024): Arrow beneficially owned 244,773 shares (including 45,815 common shares and 198,958 options exercisable within 60 days); 98,333 options were not exercisable within 60 days. Percent of class: 5% .
- Change-of-control acceleration: 100% of then‑unvested options vest upon a qualified change of control, resignation for Good Reason, or involuntary termination other than For Cause .
- Pledging/hedging: No pledging disclosure found in reviewed proxy/10-K sections .
| Ownership Detail | Amount | Notes |
|---|---|---|
| Common shares owned | 45,815 | Direct holdings |
| Options exercisable ≤60 days | 198,958 | Exercise prices include $1.74, $4.00, $5.00, $7.00 |
| Options not exercisable ≤60 days | 98,333 | Unvested/unexercisable |
| Beneficial ownership (% of class) | 5% | As of April 1, 2024 |
Outstanding option grants (Dec 31, 2024):
| Grant (Ref) | Exercisable (#) | Unexercisable (#) | Exercise Price | Expiration |
|---|---|---|---|---|
| (5) | 25,000 | — | $5.00 | Feb 12, 2026 |
| (6) | 35,000 | — | $5.00 | Apr 15, 2026 |
| (7) | 18,750 | — | $7.00 | Oct 16, 2027 |
| (8) | 10,417 | — | $4.00 | Feb 1, 2029 |
| (9) | 30,000 | — | $7.00 | Feb 13, 2030 |
| (10) | 46,874 | — | $7.00 | Feb 13, 2030 |
| (11) | 31,250 | — | $7.00 | Jul 18, 2030 |
| (12) | 25,000 | 75,000 | $1.74 | Mar 25, 2034 |
Option repricing event: On Feb 21, 2025, shareholders approved repricing authority; the Board repriced all outstanding option grants under the 2006 and 2016 plans to $0.2655 per share (closing price on Feb 21, 2025). This is a compensation governance red flag (repricing of underwater options) and may alter incentive alignment and near-term selling pressure dynamics .
Employment Terms
- Base salary and part-time arrangement: $150,000 per year; previously $125,000 until July 1, 2021 .
- Equity history: cumulative grants include 25,000 options under the 2006 plan and extensive grants under the 2016 plan (exercise prices historically at $1.74, $4.00, $5.00, $7.00) with latest 2034-dated grant at $1.74 (25,000 exercisable; 75,000 unexercisable) .
- Change-of-control economics: full acceleration of unvested options on qualified change-of-control/resignation for Good Reason/involuntary termination other than For Cause .
- Severance multiples, non-compete, non-solicit, garden leave, clawback, tax gross-ups, stock ownership guidelines: not disclosed in reviewed filings .
Performance & Track Record
- Corporate actions and restructuring: Arrow signed multiple 8-Ks reflecting governance and operating changes, including a restructuring pivot to prioritize the Phase 2 clinical trial of PT00114 and elimination of certain executive roles, transitioning to a virtual operating model to minimize burn .
- Governance signatures: Arrow signed numerous SEC filings and special meeting proxies in his capacity as CFO/Secretary .
- External value creation: Serving on the board of Paragonix, which was acquired in Sept 2024 by Getinge AB for $469 million, highlighting engagement with value-creating assets in medtech .
Risk Indicators & Red Flags
- Option repricing (Feb 2025): Repricing all outstanding options to $0.2655 per share is a governance red flag, potentially weakening pay-for-performance rigor and altering equity overhang/selling dynamics .
- Nasdaq compliance pressures: Proxies discuss reverse split authority to regain compliance with Nasdaq minimum bid and equity requirements, underscoring listing risk context during Arrow’s tenure .
Compensation Structure Analysis
- Mix shift: 2024 introduced option grant value ($32,605) after no equity value recognized in 2023/2022; overall pay remains heavily fixed (salary) with minimal variable cash incentives .
- Guaranteed vs at-risk: No cash bonus or PSU programs disclosed; equity is primarily time-based options with change-of-control acceleration; repricing materially reduces strike prices—indicative of reduced performance risk for equity holders .
- Performance metrics: No explicit revenue/EBITDA/TSR target linkages or weightings disclosed for Arrow’s incentive pay; company’s narrative references alignment via equity grants rather than metric-based plans .
Equity Ownership & Alignment
| Item | Detail |
|---|---|
| Beneficial ownership | 244,773 shares (45,815 common + 198,958 options exercisable in 60 days); 98,333 options not exercisable within 60 days; 5% of class as of April 1, 2024 |
| Ownership guidelines | Not disclosed |
| Pledging/Hedging | No pledging disclosure found |
| In-the-money value | Not calculated here; requires current market price (not in filings) |
Investment Implications
- Pay-for-performance rigor appears limited: No disclosed cash incentive plan metrics and predominantly time-based options with change-of-control acceleration; 2025 option repricing to $0.2655 materially reduces performance hurdle for equity awards—monitor dilution and exercise behavior post-repricing .
- Retention risk seems moderated by equity mechanics: Extensive vested options and change-of-control acceleration favor retention/alignment in strategic events; part-time CFO compensation structure suggests limited fixed cost burden .
- Governance and listing risk context: Reverse-split authority and Nasdaq compliance discussions signal elevated capital markets risk; CFO stewardship through restructuring and trial focus should be weighed against historical losses and TSR trajectory .