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Denise Carter

Chief Operating Officer at Quoin Pharmaceuticals
Executive
Board

About Denise Carter

Denise Carter, age 56, is co‑founder of Quoin Inc. and has served as Chief Operating Officer (COO) and director since inception in 2018; she has also been a director and COO of Quoin Pharmaceuticals Ltd. since October 28, 2021. She holds an MBA from Wharton and a B.S. in Chemistry from the College of William & Mary, with 30+ years in drug delivery and specialty pharma . Company pay‑versus‑performance shows cumulative TSR deterioration and persistent net losses across 2022–2024, relevant to incentive alignment: TSR value of a fixed $100 investment fell from $6.24 (2022) to $0.26 (2024) while net losses were $(9.4)M, $(8.7)M, and $(9.0)M respectively .

Past Roles

OrganizationRoleYearsStrategic impact
Innocoll AG (n/k/a Innocoll Biotherapeutics N.A. Inc.)President of Innocoll Pharmaceuticals; EVP Business Development & Corporate Affairs2003–2015Built BD/corporate functions; extensive life sciences fundraising and commercial exposure
West Pharmaceuticals, Inc. (drug delivery division)Vice President, Business Development2001–2003BD leadership in publicly traded drug delivery segment
Eurand (specialty pharma)Senior Director, Business Development2000–2001Specialty pharma BD experience
Fuisz Technologies (Biovail)Director, Business Development & Alliance Management1996–1999Alliances and BD in delivery technologies
Cardinal Health, Inc.Director, Business Development1999–2000Multinational healthcare BD exposure

External Roles

  • No current external directorships or committee roles disclosed for Ms. Carter .

Fixed Compensation

Metric20232024
Base Salary ($)481,800 529,980
Office Allowance ($)30,000 30,000
Automobile Allowance ($)18,000 18,000
401(k) Contributions ($)8,000 15,625
All Other Compensation ($)56,000 63,625

Notes:

  • 2024 base salary was ratified retroactive to Jan 1, 2024 under the COO Compensation Program approved by shareholders in 2024 .

Performance Compensation

ComponentMetricTargetActualPayoutVesting
Annual cash bonus (discretionary)Discretionary under employment agreement≥45% of base salary 240,900 (2023) 240,900 (2023) Cash (immediate)
264,640 (2024) 264,640 (2024) Cash (immediate)
Option awards (grant date fair value)Equity incentiveUp to 500% of fixed comp under policy/program 292,266 (2023) 292,266 (2023) 20/20/20/40 annually starting 10/26/2024
353,017 (2024) 353,017 (2024) 20/20/20/40 annually starting 12/09/2025

Option grant specifics:

Grant Date# of ADS Options (Exercisable)# of ADS Options (Unexercisable)Exercise Price ($/ADS)Vesting commencementVesting schedule
04/12/2022102 102 7,350.00 04/12/2023 4 equal annual installments
10/26/2023463 1,850 201.25 10/26/2024 20%, 20%, 20%, 40% annually
12/09/202415,332 27.30 12/09/2025 20%, 20%, 20%, 40% annually

Equity Ownership & Alignment

ItemAmountNotes
Total beneficial ownership (ordinary shares)1,049,510 4.99% of shares outstanding
Direct ordinary shares held602,630 (17,218 ADSs) Held directly
Options exercisable within 60 days21,560 ordinary (616 ADSs) Within 60 days of 07/16/2025
December 2024 warrants exercisable within 60 days425,320 ordinary (12,152 ADSs) Subject to 4.99% blocker for remainder
Outstanding options (ADSs) exercisable463 (2023) + 102 (2022) = 565 See vesting table
Outstanding options (ADSs) unexercisable1,850 (2023) + 15,332 (2024) + 102 (2022) = 17,284 See vesting table
Hedging policyHedging prohibited Applies to all directors/officers
PledgingNot disclosedNo pledging policy disclosed in proxy

Employment Terms

TermDetail
Agreement datesExecutive Employment Agreement dated March 9, 2018; amended November 9, 2021
Base salary progression$440,000 initial; increased by 9.5% to $481,800 (retro to 1/1/2023); set at $529,980 for 2024 (retro to 1/1/2024)
Target bonusDiscretionary bonus of not less than 45% of base salary
AllowancesOffice $2,500/month; automobile $1,500/month
Severance (without cause/for good reason)2 years of base salary + 2× current year’s bonus; 2 years medical benefits (unless comparable benefits at new employer)
Death/DisabilityPro‑rata bonus for year of termination; 24 months COBRA premium for disability
Change‑of‑control policyPotential vesting acceleration; option exercise extension; up to 6 additional months of pay/benefits; cash bonus up to 250% of annual base salary for CEO/COO
ClawbackSEC‑aligned clawback policy for 3 prior fiscal years of incentive comp, no fault required
Hedging/10b5‑1Hedging prohibited; pre‑clearance and blackout trading controls under Insider Trading Policy
Non‑compete/ConfidentialityCustomary non‑compete and confidentiality provisions included

Board Governance

  • Board service: Director since 2018 (Quoin Inc.), Director of Quoin Ltd. since October 28, 2021 .
  • Independence: Ms. Carter is an executive officer and not independent; independent directors are identified separately (Cooper, Culverwell, Langer, Leong, Sember) .
  • Committees: Not listed as a member of Audit, Compensation, or Nominating/Governance; those committees are composed of independent directors .
  • Attendance: Each director attended 75%+ of Board and committee meetings in the last fiscal year .
  • Dual‑role context: CEO Michael Myers also serves as Chairman with shareholder approvals for a three‑year dual‑role, indicating concentrated leadership; interim chair was appointed during reapproval window .

Director Compensation

  • Non‑employee director program does not apply to executive directors; Ms. Carter does not receive Board retainers or director option grants under the NED program .

Pay‑Versus‑Performance Context

Metric202220232024
Value of initial fixed $100 investment (TSR) ($)6.24 1.80 0.26
Net Income (Loss) ($ Millions)(9.4) (8.7) (9.0)

Compensation Structure Analysis

  • Cash vs equity mix: 2024 equity grant date fair value ($353,017) exceeded 2023 ($292,266), while cash bonus increased to $264,640 from $240,900; base rose to $529,980 under shareholder‑approved COO program .
  • Discretionary bonuses: 2023–2024 bonuses were discretionary under the employment agreement and policy, rather than formulaic performance‑metric payouts .
  • Policy latitude: New Compensation Policy allows annual equity up to 500% of fixed comp and cash bonuses up to 200% of salary for executives (CEO/COO constraints via specific programs), increasing potential variability and dilution risk if heavily utilized .
  • Option vesting structures: Multi‑year vesting (20/20/20/40) provides retention hooks; 2022 legacy options vest in four equal annual installments, extending retention horizon .

Related Party Transactions and Insider Participation

  • Pre‑merger accrual repayment: Company repaid $300,000 to Ms. Carter in each of 2023 and 2024; $1,265,000 remained outstanding as of 12/31/2024 .
  • December 2024 financing: Insiders, including Ms. Carter, participated in the $6.8M offering (aggregate insider purchases: 38,095 ADSs plus paired warrants), aligning capital support with investors .

Compensation Peer Group & Shareholder Approvals

  • Peer benchmarking: Compensation Committee engaged Aon (Radford) and considered peer survey data when increasing Ms. Carter’s base salary in 2023 .
  • Shareholder approvals: COO Compensation Program (base increases up to 15%, cash bonus up to 50% of base, annual equity up to 500% of fixed comp) was approved at the October 24, 2024 Annual Meeting and carried forward; a new compensation policy was proposed in 2025 .

Investment Implications

  • Alignment: Meaningful beneficial ownership (4.99%) and insider participation in the Dec‑2024 offering suggest skin‑in‑the‑game; hedging is prohibited, reducing misalignment risk .
  • Overhang/pressure: Large unvested option overhang (17,284 ADSs) and multi‑year vesting can create periodic selling pressure as tranches vest, especially given prior TSR declines .
  • Downside protections: Robust severance (2× bonus plus 2 years salary/benefits) and generous change‑of‑control cash bonus and acceleration policies strengthen retention but raise payout risk in adverse scenarios .
  • Governance: Executive director status and a CEO‑Chair dual‑role concentrate authority; committee independence mitigates some concerns, but continued monitoring of pay practices versus outcomes (given negative TSR/net income trends) is prudent .