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James Culverwell

Director at Quoin Pharmaceuticals
Board

About James Culverwell

Independent director at Quoin Pharmaceuticals (QNRX) since April 2021 (Quoin Inc.) and October 28, 2021 (Quoin Ltd.); age 68. He is Chair of the Audit Committee and a member of the Compensation Committee, and is deemed independent under Nasdaq rules and an “audit committee financial expert.” Prior background includes senior healthcare equity research roles at Merrill Lynch and ABN AMRO; he holds an MSc (Hons), University of Aberdeen. He is CEO and Chairman of HOX Therapeutics (since May 2013) and serves as Audit Committee Chair at TC BioPharm (Holdings) plc; he has chaired audit committees at multiple life sciences companies.

Past Roles

OrganizationRoleTenureCommittees/Impact
Merrill LynchSVP & Global Coordinator, Healthcare Research1992–2004Led global healthcare equity research coverage
ABN Amro Bank N.V.Director, Healthcare Equity Research1982–1992Led healthcare equity research
Amryt Pharma PLCDirector; Audit Committee ChairmanApr 2016–Sep 2019Chaired audit committee at a commercial-stage biopharma
Innocoll AGDirector; Audit Committee ChairmanFeb 2013–Jul 2017Chaired audit committee
Sudbrook AssociatesFounder (strategic advisory)Since 2005Strategic advice and fundraising for life sciences

External Roles

OrganizationRoleTenureCommittees/Impact
HOX TherapeuticsCEO; Chairman of the BoardSince May 2013Leads prostate cancer research company
TC BioPharm (Holdings) plcDirector; Audit Committee ChairmanSince Feb 2022Public company; audit chair
SafeGuard Biosystems (private)Director; Audit Committee Chairman; Compensation Committee memberSince Jan 2005Governance and compensation oversight (private diagnostics company)

Board Governance

  • Independence and financial expertise: The Board determined Culverwell is independent under Nasdaq rules; as Audit Committee Chair, he and all audit committee members are financially sophisticated and designated “audit committee financial experts.”
  • Committee assignments: Audit Committee Chair; Compensation Committee member (2023–2025 slates).
  • Attendance and engagement: In the last reported year (2022 data in 2023 proxy), the Board met 4x; Audit 4x; Compensation 1x; Nominating 0x; each director attended at least 75% of applicable meetings. Policy expects director attendance at AGMs; two directors attended the prior AGM.
  • Codes/policies: Code of Ethics in place; Insider Trading Policy includes pre-clearance and prohibits trading on MNPI; 10b5-1 plans permitted. Hedging is prohibited.

Fixed Compensation

Director program terms (cash retainer and committee fees):

Program YearAnnual Board Retainer ($)Committee Chair Fee ($)Committee Member Fee ($)
202260,000 15,000 5,000
202375,000
202482,500 15,000 5,000

Director-level compensation actually paid to Culverwell:

Metric202220232024
Cash fees ($)75,000 95,000 102,500
Option awards (grant-date fair value, $)163,570 27,622 33,363
Total ($)238,570 122,622 135,863

Notes:

  • 2023 director program: shareholders approved changes—annual cash retainer $75,000; annual option award value $44,000.
  • 2024 program: annual cash retainer increased to $82,500; chair fee $15,000; committee member fee $5,000.

Performance Compensation

Equity awards and vesting (director equity is time-based; no performance metrics disclosed for directors):

Grant DateInstrumentValue or QtyExercise PriceVestingNotes
Apr 12, 2022 (Initial)Stock optionsInaugural grant valued $165,000; 786 ADSs$210/ADS3-year vesting starting Apr 12, 2023Shareholders approved; plan-based grant
2022 (Annual)Stock optionsAnnual grant valued $60,000; 286 ADSs$210/ADS3-year vesting starting Apr 12, 2023
Oct 26, 2023 (Annual)Stock options$27,622 (Black-Scholes)$5.75/ADS4 equal annual installments starting Oct 26, 2024Approved at 2023 AGM
Dec 9, 2024 (Annual)Stock options$33,363 (Black-Scholes)$27.30/ADS20% on each of Dec 9, 2025, 2026, 2027; 40% on Dec 9, 2028Outstanding options per non-employee director: 1,699 ADSs at 12/31/2024

Performance metrics tied to director compensation: None disclosed; director equity is time-based options (no EPS/revenue/TSR metrics).

Other Directorships & Interlocks

CompanyListing/TypeRolePotential Interlock/Conflict Noted
TC BioPharm (Holdings) plcPublicDirector; Audit ChairNo Quoin-related interlock disclosed
HOX TherapeuticsPrivateCEO; ChairmanNo Quoin-related interlock disclosed
SafeGuard BiosystemsPrivateDirector; Audit Chair; Comp CommitteeNo Quoin-related interlock disclosed

Expertise & Qualifications

  • Audit Chair and SEC-designated audit committee financial expert; extensive public company audit and compensation committee experience.
  • Capital markets and healthcare equity research background (Merrill Lynch; ABN AMRO).
  • MSc (Hons), University of Aberdeen.

Equity Ownership

Beneficial ownership as of the 2025 proxy Record Date (each ADS represents 35 ordinary shares):

HolderTotal Beneficial Ownership (Ordinary Shares)% of ClassComposition
James Culverwell302,925 1.46% 100,310 ordinary shares (2,866 ADSs) held directly ; 2,625 ordinary shares (75 ADSs) via options exercisable within 60 days of July 16, 2025 ; 199,990 ordinary shares (5,714 ADSs) via December 2024 Warrants exercisable within 60 days

Policies:

  • Hedging of company securities by directors is prohibited under the Insider Trading Policy.

Insider Transactions

DateTransactionInstruments/QtyConsideration/TermsSource
Dec 23, 2024Participation in public offering alongside managementSeries F and G Warrants acquired; 5,714 ADSs underlying warrants within 60 days counted for CulverwellOffering raised ~$6.8M gross; combined management purchase 1,333,333 ADSs and accompanying warrants for ~$600,000 at public terms (individual ADS purchase allocation not separately disclosed)

Related-Party Exposure and Potential Conflicts

  • 2020 Notes: Culverwell was among five 2020 noteholders (with directors Langer and others). While principal converted into ADSs at the 2021 business combination, the company estimated a remaining liability to three noteholders (including Culverwell and Langer) of $1,146,000 as of December 31, 2024 related to accrued interest settlement methodology. Warrants issued to noteholders were repriced to $0.00 in July 2022 and subsequently exercised (deemed dividend of ~$65,000 across noteholders). Governance risk: continued related-party liability outstanding.
  • December 2024 Offering: Insiders, including Culverwell, participated at public terms; alignment signal but raises typical related-party optics; warrants included in beneficial ownership.

Governance Assessment

  • Positives

    • Independent director; Audit Committee Chair with “audit committee financial expert” designation—supports financial reporting oversight.
    • Multi-decade capital markets and audit committee experience across life sciences companies; current public company audit chair (TC BioPharm).
    • Director compensation structure primarily cash plus modest, time-based options; no discretionary performance metrics for directors—reduces pay-for-performance controversy at board level; option vesting multi-year.
  • Watch items / RED FLAGS

    • Related-party legacy financing (2020 Notes) with an estimated $1.146M liability outstanding to three noteholders including Culverwell and Langer; noteholder warrants were repriced to $0 in 2022 (deemed dividend) before being fully exercised—may draw investor scrutiny on process and fairness, though disclosed.
    • Director AGM attendance not specified individually; board-wide data show minimum 75% attendance; only two directors attended the prior AGM. Monitoring individual attendance disclosures in future proxies recommended.
  • Alignment signals

    • Insider participation in Dec 2024 offering on public terms; Culverwell holds direct shares, options, and warrants (1.46% beneficial ownership)—demonstrates skin-in-the-game.
    • Hedging prohibited under policy; no pledging disclosed.