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David Stump

Director at REGENXBIOREGENXBIO
Board

About David C. Stump, M.D.

David C. Stump, M.D. (age 75) has served as an independent director of REGENXBIO since October 2015. He is a physician-executive with deep R&D leadership experience in biotechnology, including senior roles at Human Genome Sciences and Genentech, and academic appointments in medicine and biochemistry. He holds an A.B. from Earlham College and an M.D. from Indiana University, with residency/fellowship training at the University of Iowa . The Board has affirmatively determined he is independent under Nasdaq standards .

Past Roles

OrganizationRoleTenureCommittees/Impact
Human Genome Sciences, Inc.EVP, Research & DevelopmentMay 2007 – Dec 2012Led late-stage development; executive oversight of R&D
Human Genome Sciences, Inc.EVP, Drug DevelopmentDec 2003 – May 2007Built development organization and programs
Human Genome Sciences, Inc.SVP, Drug DevelopmentNov 1999 – Dec 2003Senior operational leadership across drug development
Genentech, Inc.VP, Clinical Research; Genentech Fellow1989 – 1999Advanced clinical programs; scientific leadership
University of VermontAssociate Professor of Medicine & BiochemistryPrior to 1989Academic leadership in translational science

External Roles

OrganizationRoleTenureCommittees/Impact
MacroGenics, Inc. (NASDAQ: MGNX)DirectorSep 2013 – PresentPublic biotech board service; oversight of clinical pipeline
Earlham CollegeBoard of TrusteesCurrentGovernance of academic institution
Sunesis Pharmaceuticals, Inc.DirectorJun 2006 – Feb 2021Public biotech director (historical)
Portola Pharmaceuticals, Inc.DirectorSep 2015 – Jul 2020Public biotech director (historical)
Dendreon CorporationDirectorJun 2010 – Jun 2015Biotech director (historical)

Board Governance

  • Independence: Independent under Nasdaq rules; only the CEO (Curran Simpson), Chair (Kenneth T. Mills), and Allan M. Fox are non-independent .
  • Committee assignments: Audit Committee member; Nominating & Corporate Governance Committee Chair .
  • Meeting cadence and attendance: Board met 8 times in 2024; each director attended ≥75% of aggregate Board and committee meetings. Committees met: Audit (5), Compensation (8), Nominating & Corporate Governance (4) .
  • Lead Independent Director: Board has a robust Lead Independent Director role (Daniel Tassé) with clear responsibilities (executive sessions, agenda-setting, liaison) .
  • Performance evaluations: Annual self-evaluations of the Board, committees, and individual directors conducted under NC&G oversight .

Fixed Compensation

ComponentDisclosureAmount/Policy
Annual Board retainer (cash)Non-employee directors program$45,000 per director per year
Committee chair feesAudit: $20,000; Compensation: $15,000; Nominating & Corporate Governance: $10,000$10,000 (NC&G Chair) applicable to Dr. Stump
Committee membership feesAudit: $10,000; Compensation: $7,500; Nominating & Corporate Governance: $5,000$10,000 (Audit member) applicable to Dr. Stump
2024 cash fees earnedDirector Compensation Table$65,000 for Dr. Stump (consistent with Board + Audit member + NC&G chair)

Performance Compensation

Equity Element2024 Grant Value (Fair Value)Vesting TermsNotes
RSUs (annual director grant)$206,245RSUs vest in full on the first anniversary of the first day of month granted; full vesting on change in control
Stock options (annual director grant)$68,737Options vest monthly over 12 months; exercise price = FMV on grant date; full vesting on change in control
Annual director grant designAggregate $275,000 (75% options / 25% RSUs)As aboveProgram structure applies to all non-employee directors

Vesting schedules are time-based; no performance (TSR/financial) metrics are used for director equity awards .

Other Directorships & Interlocks

CompanyNatureInterlock/Context
MacroGenics, Inc.Current public company directorshipMacroGenics is included in REGENXBIO’s 2024 compensation peer group, which is selected and overseen by the Compensation Committee with Willis Towers Watson; Dr. Stump is not a member of the Compensation Committee, mitigating direct influence risk .
Sunesis, Portola, DendreonPrior public company boardsHistorical roles; no current RGNX related-party transactions disclosed .

Expertise & Qualifications

  • Deep medical and scientific background with extensive biotech R&D leadership at HGS and Genentech; academic credentials in medicine and biochemistry .
  • Board qualification emphasis: substantial experience in research, development, and operations; prior public company board service .

Equity Ownership

MetricValueDetail
Total beneficial ownership161,456 shares<1% of shares outstanding; includes exercisable options and near-term vesting RSUs as noted
Ownership % of class<1%Based on 50,116,910 shares outstanding at record date (Apr 1, 2025)
Options exercisable (or within 60 days)150,170Included in beneficial ownership; director option totals as of 12/31/24
RSUs vesting within 60 days4,790Included in beneficial ownership
Pledging/HedgingProhibited without prior approval; anti-hedging policy in placeNo pledging disclosed; company prohibits hedging, short sales, and pledging without approval .

Insider Trades (Form 4 – RGNX)

Date (Trade)Filing DateTypeSecurityQuantitySource
2025-05-302025-06-03Award (A – Grant)RSUs7,768
2024-05-312024-06-04Award (A – Grant)RSUs4,790

OpenInsider aggregate view is available for verification: (includes RGNX awards on 2024-05-31 and 2025-05-30) .

Governance Assessment

  • Strengths: Independent director; chairs Nominating & Corporate Governance Committee; active committee engagement (Audit member); annual Board/committee self-evaluations; executive sessions led by a strong Lead Independent Director .
  • Alignment: Director equity program blends options and RSUs with standard vesting and change-in-control protections; cash fees are modest and role-based; anti-hedging/pledging policy enhances alignment and risk control .
  • Attendance & engagement: Board met 8 times in 2024; each director met the ≥75% attendance threshold; Stump participates across two committees with defined mandates and 2024 meeting cadence (Audit: 5; Nominating: 4) .
  • Conflicts/RED FLAGS: No related-party transactions >$120,000 disclosed for 2024; MacroGenics in RGNX’s compensation peer group while Stump serves on MacroGenics’ board—an interlock to monitor, though he is not on RGNX’s Compensation Committee and the consultant is independent .

Overall: Governance profile is solid with clear independence, committee leadership, and standard director pay structures; limited conflict risk with an interlock noted but mitigated by committee composition and independent oversight .

Director Compensation (2024)

ComponentDr. Stump (Amount)Notes
Fees earned (cash)$65,000Board retainer plus Audit member and NC&G chair role
Stock awards (RSUs)$206,245 (grant-date fair value)Annual RSU grant; time-based vesting
Option awards$68,737 (grant-date fair value)Annual option grant; 12-month monthly vesting
Total$339,981Sum of cash + equity fair values

As of 12/31/2024, Dr. Stump held 4,790 unvested RSUs and 150,170 options outstanding .

Compensation Structure Notes

  • Non-employee directors: Annual equity $275,000 (75% options/25% RSUs); initial equity $550,000 for new directors; options strike = FMV at grant; RSUs vest annually; full acceleration upon change in control .
  • Cash program: Board retainer $45,000; committee fees per role (Audit Chair $20,000/member $10,000; Compensation Chair $15,000/member $7,500; Nominating Chair $10,000/member $5,000); pro-rated for partial service .
  • Other: Expense reimbursement and D&O insurance provided .

Related Party Exposure

  • Policy and 2024 disclosure: No related party transactions >$120,000 involving directors, officers, 5% holders or affiliates were engaged in 2024; Audit Committee pre-approves any such transactions under policy .

Compensation Committee Analysis (context)

  • Composition: Tassé (Chair), Karabelas, Glucksmann; independent; CEO excluded from decisions about own pay; Willis Towers Watson retained as independent consultant since 2019 .
  • Peer group: 2024 peer group includes MacroGenics, Ultragenyx, CRISPR, Editas, and others; annually reviewed; Radford survey data referenced .
  • Policies: Clawback for incentive-based compensation tied to financial reporting measures; anti-hedging/pledging; change-in-control double trigger vesting for executives (contextual governance strength) .

Equity Ownership Detail (Directors & Officers Snapshot)

ItemFigure
Record Date (beneficial ownership table)April 1, 2025
Shares outstanding50,116,910
Dr. Stump beneficial ownership161,456 shares; includes 150,170 options exercisable/within 60 days and 4,790 RSUs vesting within 60 days; <1% of class

Final Notes for Investors

  • Independence and committee leadership support board effectiveness; attendance thresholds met; clear governance policies (clawback, anti-hedging/pledging) bolster investor confidence .
  • Monitor interlock with MacroGenics given inclusion in RGNX’s compensation peer group; risk is moderated by compensation committee composition and independent consultant oversight .
  • No related-party transactions disclosed for 2024; director compensation structure aligns with market norms and is primarily time-based without performance targets, consistent with typical director pay practices .