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Charles Ence

Chief Accounting and Compliance Officer at RELMADA THERAPEUTICS
Executive

About Charles Ence

Charles Ence, age 65, is Chief Accounting and Compliance Officer at Relmada Therapeutics (RLMD), appointed January 2020; he previously served as CFO from July 29, 2019 to January 9, 2020 . He holds a BA in Business Administration and Accounting (Southern Utah University, 1984) and an MBA in Finance (Arizona State University, 1985) . Company-level pay-versus-performance disclosures show poor TSR in 2024 (value of $100 investment fell to $1.62), with negative “compensation actually paid” to non-PEO NEOs reflecting declines in prior award values, underscoring a difficult year and compensation restraint for 2024/2025 . The company faced a strategic pivot after disappointing REL-1017 data; management paused bonuses/LTI and shifted to in-licensing NDV-01 and acquiring Sepranolone, prioritizing cost control and pipeline diversification .

Past Roles

OrganizationRoleDatesStrategic Impact
Relmada TherapeuticsCFOJul 29, 2019 – Jan 9, 2020 Transitional finance leadership ahead of CAO role
New Age Beverages/Xing BeveragesCFOAug 2003 – Oct 2018 Led expansion to 46 states and 10 countries with consistent growth/profitability
New Age Beverages/Xing BeveragesCorporate ControllerOct 2018 – Jun 2019 Oversaw controls during late-stage growth
Quantum CorpPlanning Manager; Director of FinancePrior to On Command (dates not specified) Senior planning/finance roles
On Command CorpDirector of Finance & Investor RelationsAfter Quantum (dates not specified) IR and finance leadership
PepsiCoAnalyst→Controller (12 years)Early career (dates not specified) Progressive finance/controllership experience

External Roles

No external public company directorships or committee roles for Mr. Ence are disclosed in the proxy .

Fixed Compensation

Metric20232024
Base Salary ($)$451,438 $483,039
Target Bonus (%)40% 40%
Actual Bonus Paid ($)$520,863 $0
All Other Compensation ($)$22,734 $500,000

— The Compensation Committee determined no salary increases for 2025, no cash bonuses for 2024, and no 2024 long‑term incentive awards for NEOs, responding to performance and shareholder feedback .

Performance Compensation

Incentive Type20232024
Option Awards (Grant-Date Fair Value, $)$175,344 $0 (no options granted)
Annual Cash Bonus ($)$520,863 $0
Plan Design (qualitative)Discretionary bonus plan; corporate goals receive highest weighting for NEOs Same plan; payout suspended for 2024

The bonus plan ties payouts to Company-wide goals and individual performance; for 2024, payouts were suspended to conserve cash and align with the strategic reset .

Outstanding Equity Awards (as of Dec 31, 2024)

Grant (Strike $)ExpirationExercisable (#)Unexercisable (#)
$8.807/29/202925,000
$43.4712/19/202960,000
$33.43 (Award A)1/7/2031105,468 7,032
$33.43 (Award B)1/7/2031105,468 7,032
$19.0312/17/2031391,677 130,559
$3.37 (small lot)12/16/203218,361
$3.37 (large lot)12/16/2032250,000 250,000
$2.4812/15/203320,524 61,566

— Equity awards generally vest over four years and/or upon milestones, with plan-level change-in-control acceleration to 100% for options/RSUs and performance awards deemed at 100% of target .

Equity Ownership & Alignment

ItemDetail
Total Beneficial Ownership1,167,572 shares; 3.4% of outstanding
Direct Common Shares38,970
Vested Options (examples)25,000 @ $8.80; 60,000 @ $43.47; 112,500 @ $33.43; 112,500 @ $33.43; 456,956 @ $19.03; 312,499 @ $3.37; 18,361 @ $3.37; 30,786 @ $2.48
Unvested Options65,280 @ $19.03; 187,501 @ $3.37; 51,304 @ $2.48 (excluded from beneficial ownership)
Stock Ownership GuidelinesNot disclosed
Hedging/PledgingCompany does not currently prohibit hedging; pledging not disclosed (potential alignment risk)

Employment Terms

ProvisionTerms
Current RoleChief Accounting & Compliance Officer (appointed Jan 2020)
Employment Start & Prior RoleCFO (Jul 29, 2019 – Jan 9, 2020); CAO from Jan 2020
Base Salary (initial agreement)$275,000; Target bonus 40%; $100,000 sign‑on bonus
Current Salary Level$483,039 in 2024; no 2025 increase
Bonus Target40% of base salary
At‑Will; Non‑SolicitEmployment at‑will; 24‑month non‑solicitation post‑termination
Severance (non‑COC)Six months of compensation and health benefits
Change‑of‑ControlDouble trigger required; plan-level acceleration to 100% on options/RSUs; performance awards at 100% target
ClawbackAdopted Nov 2023; recoupment of incentive‑based comp upon certain restatements per Rule 10D‑1
Indemnification; ConfidentialityStandard indemnification; confidentiality and invention assignment agreements

Potential Payments (Dec 31, 2024 assumptions)

ScenarioCash Payment ($)Retention Compensation Agreement ($)Option Acceleration
Termination without cause/good reason (non‑COC)$338,127 $1,500,000 $0
Termination following COC (double trigger)$338,127 $1,500,000 $0

Performance & Track Record

  • At New Age Beverages, Ence led finance during expansion to 46 U.S. states and 10 countries with consistent growth and profitability, evidencing operational finance execution in consumer products .
  • Company-level TSR under RLMD’s disclosures declined sharply in 2024 (value of $100 investment to $1.62), with negative “compensation actually paid” to non-PEO NEOs, aligning with suspended bonuses/LTI for 2024/2025 .

Compensation Committee Analysis

  • Compensation Committee members: Chair Charles J. Casamento; members John Glasspool and Fabiana Fedeli; independent oversight with twice-held meetings in 2024 .
  • Program emphasizes pay-for-performance, uses Radford Global Compensation database benchmarking pre-commercial biotech peers; no explicit named peer list disclosed .
  • Response to 2024 say-on-pay “negative” vote: investor outreach, disclosure enhancements, and suspension of salary increases, cash bonuses, and LTI grants for 2024/2025 until strategic value creation milestones achieved .

Risk Indicators & Red Flags

  • Anti-hedging: The company does not currently prohibit hedging; potential misalignment risk if insiders hedge exposure .
  • Equity acceleration on change-of-control: 100% immediate exercisability and vesting; performance awards deemed at target—could incentivize sale outcomes regardless of long-term performance .
  • Retention compensation: Material retention cash in lieu of unapproved equity (e.g., $500,000 in 2024; $1.5M in severance scenarios)—reduces at-risk pay mix .
  • Say-on-pay: Negative outcome in 2024; indicates shareholder concerns around pay practices .
  • Legal proceedings: No material adverse proceedings for executives in the past ten years disclosed .

Equity Ownership & Alignment (Detail)

ComponentAmount
Beneficial Ownership (% of SO)3.4%
Beneficial Ownership (shares)1,167,572
Direct Common Shares38,970
Vested Options – totals by strike (counts)See list above (e.g., 456,956 @ $19.03; 312,499 @ $3.37)
Unvested Options – totals by strike (counts)65,280 @ $19.03; 187,501 @ $3.37; 51,304 @ $2.48

Investment Implications

  • Alignment: Significant vested/unvested option holdings and 3.4% beneficial stake align Ence’s incentives with equity value; however, the absence of anti-hedging restrictions and COC acceleration weaken long-term alignment under certain scenarios .
  • Retention & Selling Pressure: Large blocks of low-strike options (e.g., $2.48/$3.37) plus scheduled vesting could create future sell pressure upon window openings; retention cash supplants at-risk equity for 2024, signaling conservative cash preservation but diluting pay-for-performance for the period .
  • Contract Economics: Double-trigger COC protections with plan-level acceleration and defined severance ($338k cash + $1.5M retention component) suggest manageable transaction costs, but acceleration mechanics could drive near-term realization over multi-year execution .
  • Execution Risk: Track record in scaling consumer finance operations is strong, but RLMD’s 2024 TSR collapse and strategic pivot imply heightened execution risk; compensation restraint indicates management responsiveness to shareholder signals .