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Charles J. Casamento

Chairman of the Board at RELMADA THERAPEUTICS
Board

About Charles J. Casamento

Charles J. Casamento (age 78) is Chairman of the Board at Relmada Therapeutics, Inc. (RLMD), serving as a director since July 2015 and Chairman since June 2017. He is an independent director under Nasdaq rules and sits on the Audit, Compensation, and Corporate Governance & Nominating Committees; he has chaired the Compensation Committee since January 1, 2023. Casamento holds a Pharmacy degree from Fordham University and an MBA from Iona University, and has led multiple biopharma companies including Questcor Pharmaceuticals and Interneuron/Indevus, with senior roles at Genzyme, Novartis, Hoffmann-LaRoche, Johnson & Johnson, and American Hospital Supply.

Past Roles

OrganizationRoleTenureCommittees/Impact
The Sage GroupExecutive Director & PrincipalSince 2007Healthcare advisory group focusing on BD strategy and transactions
OsteologixPresident & CEOOct 2004 – Apr 2007Led company operations
Questcor PharmaceuticalsChairman, CEO & PresidentMerger in 1998; through Aug 2004Oversaw post-merger leadership; company later acquired by Mallinckrodt
RiboGeneChairman, President & CEOFrom 1993; merged in 1998Took company public; executed major collaborations; merger formed Questcor
Interneuron (Indevus)Co-founder & CEOFrom 1989Company later acquired by Endo Pharmaceuticals
GenzymeSVP & GM, Pharmaceuticals & BiochemicalsUntil 1989Senior leadership in pharma/biochemicals
American Hospital Supply Corp.VP, BD & Strategic Planning, Critical Care DivisionJan 1983 – May 1985Led BD/strategy in critical care
Novartis; Hoffmann-LaRoche; Johnson & JohnsonVarious roles in marketing, sales, finance, BDPrior to 1985Foundational commercial and BD experience

External Roles

CompanyRoleStatusCommittees/Notes
Eton Pharmaceuticals, Inc.Independent DirectorCurrentPublic company board service
GT Biopharma, Inc.Independent DirectorCurrentPublic company board service
First Wave Biopharma, Inc.Independent DirectorPrior (listed 2024 proxy)Public company board service
PaxMedica, Inc.Lead Independent DirectorPrior (listed 2024 proxy)Lead independent oversight
Multiple boards historicallyDirector14 public, 2 privateCareer total board service

Board Governance

  • Independence: RLMD identifies Casamento as an independent director under Nasdaq Listing Rule 5605(a)(2).
  • Roles: Chairman of the Board; member of Audit, Compensation, and Corporate Governance & Nominating; Compensation Committee Chair since 1/1/2023.
  • Attendance: Board met 5 times in FY2024 and all directors attended; in FY2023, Board met 4 times and all directors attended. Audit Committee met 4 times in 2024; Compensation Committee met 2 times; Corporate Governance & Nominating met 4 times.
  • Tenure: Director since July 2015; Chairman since June 2017.
  • Lead Independent Director: Not disclosed.
  • Executive sessions: Not disclosed.

Fixed Compensation

ComponentFY2024 AmountNotes
Board Cash Retainer$17,655 per quarter ($70,620 total) Standard for non-management directors
Chairman of the Board Fee$67,089 Additional cash compensation for chair duties
Committee Fees (2025 Schedule; unchanged vs 2024)Audit Chair $23,540; Audit Member $10,593; Compensation Chair $17,067; Compensation Member $8,239; Nominating Chair $17,067; Nominating Member $8,239 Annual fees for committee participation
ReimbursementsOut-of-pocket expenses reimbursed Standard practice

Director-specific FY2024 compensation:

YearFees Earned or Paid in CashStock AwardsOption AwardsAll Other CompensationTotal
2024$173,608 $0 $0 $180,000 $353,608
2023$162,250 $0 $67,331 $0 $229,581

Notes:

  • The "All Other Compensation" column in 2024 reflects cash paid in replacement of stock options not approved at the annual shareholder meeting.

Performance Compensation

ElementGrant ActivityTermsPerformance Metrics
Stock Options (Director)No options granted to Board members in 2024; options granted in 2023 (grant-date FV $67,331 for Casamento) Plan requires exercise price ≥ FMV; typical 10-year term; vesting per award agreement No director-specific performance metrics disclosed for equity grants; director compensation is primarily time-based

Plan provisions (applicable to director awards):

  • Change-in-control: Outstanding options/SARs become immediately exercisable; restricted stock/RSUs restrictions lapse; performance awards deemed at 100% of target (award agreements may specify otherwise).
  • Clawback: Company adopted clawback policy in Nov 2023 for executive officers under Rule 10D-1 and Nasdaq; director awards are not specifically addressed in the clawback narrative.

Other Directorships & Interlocks

CompanyRelationship to RLMDPotential Interlock/Conflict
Eton Pharmaceuticals, GT BiopharmaExternal boardsNo RLMD-related transactions disclosed; independence affirmed
First Wave Biopharma, PaxMedica (2024 disclosure)External boardsNo RLMD-related transactions disclosed

Expertise & Qualifications

  • Education: Pharmacy degree (Fordham University) and MBA (Iona University).
  • Executive experience: CEO/Chairman roles across multiple biopharma companies; senior roles at Genzyme; extensive BD and strategic planning.
  • Board service: Extensive board experience (14 public, 2 private).

Equity Ownership

As ofTotal Beneficial Ownership (Shares)Ownership %Breakdown
Mar 27, 2025661,371 2.0% Footnote indicates 0 common shares held directly; beneficial ownership composed of vested options: 6,441 ($13.80), 11,704 ($3.24), 81,406 ($4.60), 125,000 ($8.80), 100,000 ($43.47), 100,000 ($33.43), 131,250 ($19.03), 93,750 ($3.37), 11,820 ($2.48); excludes unvested options 18,750 ($19.03), 56,250 ($3.37), 19,702 ($2.48)
Mar 27, 2024552,051 1.8% Footnote lists vested options and excludes unvested options; includes 6,441 ($13.80), 11,704 ($3.24), 81,406 ($4.60), 125,000 ($8.80), 100,000 ($43.47), 81,250 ($33.43), 84,375 ($19.03), 46,875 ($3.37), 15,000 ($2.48); excludes unvested 18,750 ($33.43), 65,625 ($19.03), 103,125 ($3.37), 225,000 ($2.48)

Policy flags:

  • Anti-hedging: Company does not currently prohibit hedging transactions for employees, officers, or directors. No pledging disclosure noted.

Governance Assessment

  • Strengths:

    • Independent director with deep biopharma operating experience; chairs Compensation Committee and contributes to all three committees.
    • Board/committee engagement: RLMD held 5 board meetings in 2024 and all directors attended; key committees met multiple times.
    • Ownership alignment: Material beneficial ownership via vested options; increased beneficial ownership from 2024 to 2025.
  • Watch items / RED FLAGS:

    • Anti-hedging policy absence for directors and officers is a governance risk; hedging can weaken alignment.
    • 2024 say-on-pay failed; RLMD acknowledged a negative vote and undertook investor engagement and plans to refine pay practices (indicator of shareholder concern).
    • Shift from equity to cash in director pay: 2024 features “All Other Compensation” replacing options not approved by shareholders and no options granted to directors (reduction in at-risk equity), which may dilute performance alignment if sustained.
    • Equity plan share increases could be dilutive; board sought additional shares (2.0M in 2025; 4.5M in 2024), which requires careful oversight to avoid pay inflation.

Committee Assignments, Chair Roles, and Expertise

CommitteeMembershipChair2024 MeetingsNotes
CompensationMember; Chair since 1/1/2023 Charles J. Casamento 2 Oversees executive/director pay; submitted CD&A report
AuditMember Fabiana Fedeli 4 Signed Audit Committee report
Corporate Governance & NominatingMember John Glasspool 4 Board composition and governance policy oversight

Director Compensation Mix and Year-over-Year Analysis

YearCash Retainer & Chair FeesEquity (Options)Other Cash (replacing options)Mix Commentary
2024$173,608 cash fees $0 $180,000 No options granted to directors; cash paid in lieu of options not approved—reduced equity risk exposure
2023$162,250 cash fees $67,331 option awards (FV) $0 Traditional cash + options mix; subsequent year moved to cash replacement

Related-Party Exposure

  • RLMD disclosed related party items (e.g., psilocybin license with Arbormentis and affiliations of scientific advisors) but no transactions involving Casamento.
  • No loans or personal arrangements disclosed for Casamento.

Compensation Peer Group and Consultant Use (Context)

  • RLMD uses Radford Global Compensation data and external consultants for executive pay benchmarking and reviews director pay practices versus peers (no specific director peer list disclosed).

Say-on-Pay & Shareholder Feedback

  • 2024 vote: Negative say-on-pay outcome; company engaged major investors and committed to disclosure and framework improvements.
  • 2021 advisory vote: 93.4% support (historical context as a smaller reporting company).

Employment & Contracts (Director-Specific)

  • No director employment contracts disclosed; director compensation covered by board-approved retainers and equity plans.

Equity Ownership Guidelines

  • Director stock ownership guidelines: Not disclosed.

Risk Indicators & Signals

  • Anti-hedging policy absent (risk of misaligned incentives).
  • Equity plan dilution risk (requests to increase authorized shares).
  • Governance continuity: High attendance and stable committee operations.

Summary Implications for Investors

  • Casamento brings veteran biopharma leadership and active committee oversight, supporting board effectiveness; independence and attendance are positives.
  • Recent compensation structure shift toward cash due to shareholder constraints, combined with absent anti-hedging policy, warrants monitoring of incentive alignment and future equity grant practices.
  • The failed 2024 say-on-pay indicates investor scrutiny of pay design; board engagement and planned refinements are constructive, but follow-through should be tracked.