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Michael MacLean

Chief Financial Officer at Avidity Biosciences
Executive

About Michael MacLean

Michael F. MacLean is Chief Financial Officer of Avidity Biosciences (RNA), serving since May 2020; he also held the Chief Business Officer role from April 2022 through December 2024 . He holds a B.S. in Accounting from Boston College and currently serves on the board of Verve Therapeutics (since June 2021) . As of April 2024 he was 58 years old . Pay-versus-performance disclosures show 2024 company TSR translated into a $162 value of a $100 initial investment (peer group $117) alongside a 2024 net loss of $322.3 million, framing the performance context for incentive outcomes .

Past Roles

OrganizationRoleYearsStrategic Impact
Akcea Therapeutics, Inc.Chief Financial OfficerSep 2017–Mar 2020Led finance during commercialization of rare disease therapies under parent Ionis
PureTech Health plcChief Financial Officer & EVPSep 2015–Aug 2017Finance leadership at clinical-stage biopharma platform
Iron Mountain Inc. (North American business)Chief Financial OfficerJul 2014–Jun 2015Regional CFO for information management leader
Iron Mountain Inc.SVP, Worldwide ControllerOct 2012–Jun 2014Global finance operations leadership
Biogen Inc.SVP Finance & Chief Accounting OfficerNot disclosedLed Biogen’s worldwide finance organization

External Roles

OrganizationRoleYearsNotes
Verve TherapeuticsDirectorJun 2021–presentPublic company board service

Fixed Compensation

MetricFY 2022FY 2023FY 2024
Base Salary ($)451,500 471,900 490,800
Target Bonus % of Salary40% 40% 40%
Actual Cash Bonus Paid ($)234,800 188,760 331,300
All Other Compensation ($)15,336 14,082 17,010

Perquisites detail (2024): Life insurance premiums $1,410; 401(k) match $13,800; work-from-home stipend $1,800 . Company matches 401(k) at 100% up to 4% of eligible compensation . The company does not provide post-employment tax gross-ups .

Performance Compensation

Annual Cash Incentive (Short-Term)

YearMetricWeightingTargetActual Payout ($)Payout vs TargetVesting
2024Corporate performance goals (with individual adjustment)100% corporate with individual multiplier 40% of base salary; plan-based target shown $238,545 331,300 Paid at 150% of target Cash paid annually
2023Corporate performance goals (with individual)As above 40% of base salary 188,760 Not disclosedCash paid annually
2022Corporate performance goals (with individual)As above 40% of base salary 234,800 Not disclosedCash paid annually

Long-Term Equity Awards (2024 Grants)

Grant DateInstrumentQuantityExercise PriceFair Value ($)Vesting SchedulePerformance Link
1/20/2024Stock Options106,000 $10.16 762,172 Equal monthly over 4 years Stock price appreciation only
1/20/2024RSUs22,500 228,600 4 equal annual installments Time-based
10/30/2024PSUs72,000 3,111,840 3 equal tranches upon milestone achievement by 12/31/2029 del‑desiran, del‑brax, del‑zota goals; eligible to vest in full on change-in-control

Equity vehicle design: options at FMV on grant; options typically vest monthly over 4 years; RSUs vest annually over 4 years; PSUs provide performance-based alignment with product milestones .

Outstanding Equity (as of Dec 31, 2024)

InstrumentGrant DateExercisable (#)Unexercisable (#)Exercise Price ($)ExpirationUnvested Shares/Units (#)Market Value ($)
Options2/2/2021 (vc 1/1/2021)90,083 1,917 22.34 2/2/2031
Options1/21/2022 (vc 1/3/2022)95,703 35,547 14.22 1/21/2032
Options1/20/202370,916 77,084 22.47 1/20/2033
Options9/11/20239,250 50,875 6.57 9/11/2033
Options1/20/202424,291 81,709 10.16 1/20/2034
RSUs1/20/202313,875 403,485
RSUs9/11/202325,000 727,000
RSUs1/20/202422,500 654,300
PSUs10/30/202472,000 2,093,760

Vesting mechanics: Options vest monthly over 4 years; RSUs vest annually over 4 years; PSUs vest in three performance tranches; PSUs eligible for full vesting at change-in-control .

Equity Ownership & Alignment

ItemDetail
Total Beneficial Ownership473,232 shares; less than 1% of outstanding
Options included in Beneficial Ownership465,514 options exercisable within 60 days of 4/15/2024
Ownership GuidelinesNot disclosed
Hedging/PledgingHedging and pledging prohibited by Insider Trading Policy
ClawbackCompany maintains clawback policy per SEC/Nasdaq rules

Employment Terms

ProvisionOutside CIC TerminationCIC Termination (Double Trigger)Post-Termination Option Window
Salary SeveranceLump sum equal to 12 months base salary Lump sum equal to 18 months base salary If terminated for cause: 3 months to exercise vested options; without cause or for good reason: 6 months; never beyond original expiration
Bonus Severance150% of target bonus (lump sum) plus prorated target bonus (lump sum)
Health BenefitsCOBRA premiums paid up to 12 months COBRA premiums paid up to 18 months
Equity AccelerationNone (time-based awards not accelerated) Accelerated vesting of unvested time-based awards; PSUs eligible for full vest on CIC
CIC WindowNot applicableTermination occurs within 59 days prior to or 24 months after a CIC

Potential payments (assuming event on 12/31/2024):

ScenarioCash Severance ($)Accelerated Equity ($)Health Benefits ($)Total ($)
Involuntary Termination Without Cause/Good Reason apart from CIC490,800 11,013 501,813
Involuntary Termination Without Cause/Good Reason in connection with CIC1,030,680 7,620,350 16,520 8,667,550
CIC (No Termination)2,820,760 2,820,760

Key definitions (from employment agreement): “Cause,” “Good Reason,” and “Change of Control” terms detailed; agreement includes relocation assistance provisions (historical) .

Investment Implications

  • Pay-for-performance alignment: Annual cash incentives paid at 150% of target in 2024 indicate strong corporate goal achievement; long-term mix emphasizes options and RSUs with added PSUs tied to specific asset milestones, reinforcing equity-driven alignment .
  • Retention and selling pressure: Monthly option vesting and annual RSU vesting provide ongoing retention; sizable 2024 PSU grant (72,000 units) eligible to vest in full upon a change-in-control could create event-driven supply if a CIC occurs, but performance gating to 2029 mitigates near-term release risk .
  • Change-in-control economics: Double-trigger severance with 18 months salary + 150% target bonus, prorated bonus, and accelerated time-based vesting raises retention value but increases potential CIC costs; PSUs’ CIC eligibility further amplifies CIC-related payouts .
  • Governance safeguards: No tax gross-ups, anti-hedging/anti-pledging policy, and clawback framework reduce governance risk; no disclosed stock ownership guideline metrics for executives limits the ability to assess mandated “skin-in-the-game” thresholds .

Overall: MacLean’s package is levered to milestone execution and stock performance, with material CIC protections and PSU exposure. Monitoring PSU milestone progress (del‑desiran, del‑brax, del‑zota) and any CIC signals is critical for anticipating compensation outcomes and potential insider selling dynamics .