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Freda Nassif

Chief Business Officer at CASSAVA SCIENCESCASSAVA SCIENCES
Executive

About Freda Nassif

Freda Nassif is Chief Business Officer at Cassava Sciences (SAVA), age 49, with 25 years of commercial leadership at Pfizer, Novartis, Merck, and Bristol‑Myers Squibb, and recent work with biotech startups and healthcare investment firms on diligence and BD strategy; she holds an MBA and BS from Drexel University . She joined Cassava in November 2024, initially as Chief Commercial Officer, and is now part of the executive team covered by companywide insider trading and clawback policies .

Past Roles

OrganizationRoleYearsStrategic Impact
PfizerFranchise leadershipNot disclosedCommercial strategy, market development
NovartisFranchise leadershipNot disclosedCommercial operations and strategy
MerckFranchise leadershipNot disclosedCommercial strategy and execution
Bristol‑Myers SquibbFranchise leadershipNot disclosedBrand strategy and commercialization
Biotech startups; healthcare-focused investment firmsAdvisor/partnerNot disclosedPre/post-investment diligence; BD opportunities; strategic alliances

External Roles

OrganizationRoleYearsNotes
None disclosedNo public directorships disclosed for Nassif

Fixed Compensation

Component2024/2025 TermsNotes
Base Salary$475,000Set at hire (Nov 2024)
Target Bonus %40% of base (prorated for partial year)Annual bonus based on performance criteria to be established by Board
Actual BonusNot disclosedNo individual bonus disclosure for Nassif

Performance Compensation

Equity Awards and Vesting

Award TypeGrant DateQuantityExercise PriceVesting Schedule
Stock options (2018 Omnibus Plan)Nov 18, 2024100,000Closing price on grant date25% annually starting on grant date anniversary (four equal annual installments)
Vesting Tranches2025202620272028
Shares vesting25,000 25,000 25,000 25,000

Annual Incentive Plan Parameters

MetricWeightingTargetActualPayoutVesting/Timing
Annual cash bonusNot disclosed40% of base (prorated 2024) Not disclosedNot disclosedAnnual, based on Board-set performance criteria

Notes:

  • No PSUs/RSUs disclosed for Nassif; options are the primary equity incentive .
  • Companywide clawback policy (Oct 2, 2023) applies to covered executive officers and incentive compensation tied to financial reporting measures .

Equity Ownership & Alignment

ItemDetail
Total beneficial ownershipNot disclosed in 2025 proxy’s ownership table (covers directors and NEOs)
Options outstanding100,000; 4-year ratable vesting; 10-year term; exercise price at grant-date close
Exercisable vs. unexercisableTranches vest annually; first 25% on Nov 18, 2025
Hedging/PledgingHedging prohibited; pledging/margin accounts prohibited unless approved by Compliance Officer; mandatory pre‑clearance for trades
Ownership guidelinesNone; company has no stock ownership guidelines

Employment Terms

TermDetail
Position/titleHired as Chief Commercial Officer (Nov 18, 2024); currently Chief Business Officer
Agreement dateNov 15, 2024 (effective Nov 18, 2024)
Contract termIndefinite; continues unless terminated under agreement
Base and bonus$475,000 base; 40% target bonus (prorated for partial year)
Equity grant100,000 options; 25% annual vesting; exercise price = grant-date close
Severance (no cause/Good Reason)After 180 days of employment: 3 months of base salary + benefits; requires release
Change-in-Control economicsIf terminated without cause after CoC: 12 months of base salary + benefits; requires release
Good Reason definitionIncludes material salary reduction; material breach; adverse change in duties; management reporting change; certain relocations (post‑relocation)
Relocation assistanceProvided if relocating to Austin; clawback if voluntary resignation within 6 months post‑relocation
Non‑compete / Non‑solicitNot disclosed in agreement; confidentiality and IP assignment covenants included
Arbitration/Governing lawMandatory arbitration (AAA Employment Rules); Texas law and courts for enforcement

Investment Implications

  • Pay-for-performance alignment: Nassif’s equity is entirely in stock options with 4-year ratable vesting, aligning upside with shareholder value creation; annual bonus targets exist but specific metrics are set by the Board and not disclosed . Company’s clawback policy adds discipline on incentive compensation tied to financial reporting measures .
  • Retention and selling pressure: Vesting of 25,000 options annually through 2028 creates predictable potential supply from option exercises over time; severance is modest (3 months) under standard termination, with enhanced 12-month coverage only upon termination after a change in control .
  • Governance and trading risk mitigation: Prohibitions on hedging and pledging, mandatory trade pre‑clearance, and no ownership guidelines reduce misalignment risks but also mean executives aren’t required to hold stock beyond awards .
  • Context on shareholder sentiment: Say‑on‑pay support was 83% in 2024 and 2025 advisory vote passed (6.22M for; 1.67M against), suggesting broad support for the company’s compensation framework, though Nassif was not an NEO in these disclosures .