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Henry Ji

Chief Executive Officer at Scilex Holding
CEO
Executive
Board

About Henry Ji

Henry Ji, Ph.D. is Executive Chairperson and, since 2025, Chief Executive Officer of Scilex Holding Company; he has served on Scilex boards since 2016, previously running Scilex Pharmaceuticals as CEO (2016–2019). He is 60 years old (as of May 1, 2025), holds a Ph.D. in Animal Physiology from the University of Minnesota and a B.S. in Biochemistry from Fudan University, and brings 20+ years of biopharma leadership including founding roles and C‑suite positions at Sorrento Therapeutics and Stratagene Genomics . Under his board leadership, Scilex’s revenue increased year over year in FY 2024 while EBITDA losses narrowed; the company also executed a 1‑for‑35 reverse split in April 2025 and later regained Nasdaq minimum bid compliance, both relevant to equity incentives and insider trading windows .

Company performance (recent fiscal years):

MetricFY 2023FY 2024
Revenues ($USD)$46,743,000 $56,590,000
EBITDA ($USD)-$101,285,000*-$88,741,000*

Values marked with * retrieved from S&P Global.

Past Roles

OrganizationRoleYearsStrategic Impact
Scilex Pharmaceuticals Inc.Chief Executive OfficerNov 2016 – Mar 2019Led subsidiary operations; joined Scilex Pharma board in 2016 .
Semnur (wholly owned subsidiary)Treasurer, Secretary, DirectorSince 2013Founding governance of pain-focused subsidiary .
Stratagene Genomics, Inc. (subsidiary of Stratagene)Co‑founder; President & CEO1997 – 1999Led genomic subsidiary startup within Stratagene .
CombiMatrix CorporationVice President2001 – 2002Managed strategic technology alliances .
Stratagene CorporationDirector Business Dev.; VP1999 – 2001Led licensing and product development .

External Roles

OrganizationRoleYearsNotes
Sorrento Therapeutics, Inc.Co‑founder, Director (since 2006); CSO (2008–2012); Interim CEO (2011–2012); CEO & President (since 2012); Chairman (since 2017)2006 – presentCurrent executive leadership and board chair at a public biopharma; significant network interlock .
Vivasor Holding Company; Vivasor, Inc.Chief Executive OfficerCurrentAdditional operating roles noted in 2025 proxy .
BioVintage, Inc.Founder; PresidentSince 2002R&D company in innovative life sciences .
Celularity Inc. (Nasdaq: CELU)DirectorJun 2017 – Jul 2021Prior public board service .

Fixed Compensation

YearBase Salary ($)Target Bonus (%)Cash Bonus ($)Stock Awards ($)Option Awards ($)All Other Compensation ($)Total ($)
2023821,465 150% (set Sep 22, 2023, effective Oct 16, 2023) 33,034,320 63,965 33,919,750
20241,250,000 150% (no change in 2024) 11,651 1,261,651

Notes:

  • Compensation Committee approved Dr. Ji’s base salary increase to $1,250,000 and bonus target of 150% on Sep 22, 2023, effective Oct 16, 2023 . Committee made no changes to NEO salary/bonus targets in 2024 .

Performance Compensation

Option awards and vesting:

Grant DateTypeSharesExercise PriceVestingAcceleration
Sep 20, 2019Director stock option58,048$60.55/shareFully vestedN/A .
Jan 17, 2023Stock option257,142$282.80/share1/48 monthly over 48 monthsFull acceleration upon Change in Control; options remain exercisable ≥24 months post‑CIC .
Oct 4, 2023Stock option5,714$49.35/share1/48 monthly over 48 monthsFull acceleration upon Change in Control; options remain exercisable ≥24 months post‑CIC .

Additional disclosures:

  • Committee did not change NEO salary/bonus targets in 2024; specific performance metrics, weightings, and payout formulas for cash bonuses are not disclosed in proxies (scaled EGC disclosure) .
  • Option Repricing proposal (Nov 2025): Dr. Ji had 440,733 options outstanding (price range $17.58–$282.80), with 257,142 “Eligible Options” at $282.80 targeted for repricing; NEOs/directors held ~94% of Eligible Options (group) — potential compensation structure modification and dilution risk .

Equity Ownership & Alignment

Beneficial ownership (includes options/warrants exercisable within 60 days of the stated date, per SEC rules):

MetricMar 6, 2024Jan 31, 2025May 1, 2025Oct 17, 2025
Common shares beneficially owned5,093,288 7,658,425 235,065 267,736
% of common outstanding2.98% 3.06% 3.28% 3.41%
Options exercisable ≤60 days (included above)4,490,041 6,977,541

Policies affecting alignment and selling pressure:

  • Hedging/short sales prohibited; options trading and short‑term trading restricted; pledging restricted and requires pre‑clearance with demonstrated capacity to repay without resort to pledged shares . The 10‑K Insider Trading Policy states margin accounts and pledging are prohibited for directors and officers .
  • Clawback policy compliant with SEC Rule 10D‑1 and Nasdaq 5608: recoupment of erroneously awarded incentive compensation for 3 completed fiscal years preceding any accounting restatement; applies to stock price/TSR‑based awards via reasonable estimation .

Employment Terms

TermKey Provision
Employment agreementScilex has not entered into an offer letter or employment agreement for Dr. Ji’s service as Executive Chairperson or Chief Executive Officer .
Severance (no CIC)If terminated without cause or resigns for good reason prior to a change in control: one year base salary (paid monthly), 12 months of benefits, vested options exercisable for 24 months (or earlier expiry) .
Change‑in‑control (CIC)Upon a CIC (single‑trigger): lump sum equal to 3× annual base salary and 3× target bonus, plus $3,000 × 36 for benefits; accelerated vesting of all time‑based equity awards; options exercisable for ≥24 months post‑CIC .
Equity vesting mechanicsOptions vest 1/48 monthly over 48 months; certain plan footnotes provide for full acceleration if awards are not assumed in a Corporate Transaction, and double‑trigger acceleration within 13 months after a CIC under the 2019 plan footnote context .
ClawbackCompany policy filed as Exhibit 97.1 to FY 2023 10‑K; administered by Compensation Committee .

Board Governance

  • Board service history: Executive Chairperson since Sep 22, 2023; previously Executive Chairperson Nov 2022–Aug 2023; Class III director, nominated to serve through 2028 if elected .
  • Committee roles: Member of the Commercialization and Transaction Committee (C&T Committee); Audit, Compensation, and Nominating/Corporate Governance committees are composed of independent directors .
  • Independence: Board determined a majority of directors are independent under Nasdaq rules; Dr. Ji and Mr. Shah are not independent due to executive roles .
  • Attendance: In FY 2024, Board held 8 meetings; directors (other than one due to conflicts) attended ≥75% of Board/committee meetings; employee directors receive no additional director compensation .

Performance & Track Record

  • Company metrics under board oversight: Revenues grew from $46.7m in FY 2023 to $56.6m in FY 2024; EBITDA loss narrowed year-over-year, supporting a directional improvement in operating leverage . EBITDA values from S&P Global: FY 2023 −$101.3m*; FY 2024 −$88.7m*.
  • Capital structure actions: 1‑for‑35 reverse stock split effected April 15, 2025; unless otherwise indicated, proxy share/per‑share amounts reflect retroactive adjustment . Company announced regaining compliance with Nasdaq minimum bid price April 30, 2025 .

Values marked with * retrieved from S&P Global.

Compensation Structure Analysis

  • Equity‑heavy pay mix in 2023 (large option award grant), followed by no new option grants for Dr. Ji in 2024; cash base increased to $1.25m with unchanged 150% target bonus, indicating higher fixed cash with ongoing at‑risk bonus .
  • Options vest monthly over 48 months, creating a steady cadence of potential exercisability and, if 10b5‑1 plans are on file, possible periodic insider sales; policy‑mandated pre‑clearance and blackout windows mitigate timing risks .
  • Option Repricing proposal (Nov 2025) to address deep‑out‑of‑the‑money grants (e.g., $282.80 strike) is a red flag for pay‑for‑performance alignment and potential dilution, though it may restore retention value and incentive efficacy amid post‑split trading dynamics .

Equity Ownership & Alignment

  • Material beneficial ownership with a significant portion represented by options exercisable within 60 days; ownership percentages remained ~3–3.4% across 2024–2025 measurement dates, despite reverse split and share count changes, indicating durable economic exposure .
  • Hedging prohibited; pledging restricted/pre‑clearance required or prohibited per policy; combined with clawback, governance frameworks reduce misalignment risk from derivative hedges or leverage against company stock .

Risk Indicators & Red Flags

  • Option Repricing proposal targeting high‑strike options held largely by insiders (approx. 94% of eligible options held by three non‑employee directors and two executives), suggesting potential dilution and governance sensitivity to retention incentives .
  • Single‑trigger CIC cash severance (3× salary and 3× target bonus) plus full acceleration could create perceived windfall risk in a transaction; investors often prefer double‑trigger structures .
  • Leadership transitions: Former CEO Jaisim Shah resigned Aug 17, 2025; director resignation Sep 22, 2025 — execution continuity risk and board composition shifts .

Investment Implications

  • Alignment: Large, long‑dated option exposure with monthly vesting, clawback enforcement, and hedging/pledging restrictions support alignment; however, proposed option repricing and single‑trigger CIC benefits weaken pay‑for‑performance optics and increase dilution/transaction windfall risk .
  • Retention/trading signals: Underwater options and reverse split dynamics increase the likelihood of compensation adjustments; monthly vesting and 10b5‑1 plan allowances can drive periodic insider trading activity (subject to pre‑clearance/blackouts), which traders may monitor for sentiment and liquidity signals .
  • Execution risk: CEO succession in 2025 and governance changes warrant scrutiny; despite revenue growth and improving EBITDA trajectory, high CIC multiples and potential repricing indicate balancing retention with shareholder dilution considerations .