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Terrance McGuire

Director at Seer
Board

About Terrance McGuire

Terrance McGuire (age 69) is an independent director of Seer, Inc., serving on the board since 2017. He is a founding partner of Polaris Partners with a venture background in early-stage medical and IT investing, and holds a B.S. in Physics & Economics (Hobart), an M.S. in Engineering (Dartmouth Thayer), and an M.B.A. (Harvard Business School). He is Chair of Seer’s Talent & Compensation Committee and a member of the Audit Committee; Seer’s board has affirmatively determined he is independent under Nasdaq rules.

Past Roles

OrganizationRoleTenureCommittees/Impact
Polaris PartnersFounding PartnerSince 1996 (current)Corporate development and strategy expertise cited in board biography
Burr, Egan, Deleage & Co.Investor (early-stage medical and IT)Seven years prior to 1996Early-stage investing background

External Roles

OrganizationRoleStatusNotes
Invivyd, Inc. (formerly Adagio Therapeutics, Inc.)DirectorCurrentPublic company board service
Tectonic TherapeuticDirectorCurrentPrivate company (not specified as public in proxy)
Whitehead InstituteDirector/TrusteeCurrentNon-profit research institute
Acceleron Pharma, Inc.DirectorFormerPublic company board service (historical)
Alector, Inc.DirectorFormerPublic company board service (historical)
Arsanis, Inc.DirectorFormerPublic company board service (historical)
Cyclerion Therapeutics, Inc.DirectorFormerPublic company board service (historical)
Ironwood Pharmaceuticals, Inc.DirectorFormerPublic company board service (historical)
Pulmatrix, Inc.DirectorFormerPublic company board service (historical)
The David H. Koch Institute at MITBoardFormerAcademic/research governance
HBS Arthur Rock Center for EntrepreneurshipBoardCurrentAdvisory/board role
Dartmouth Thayer School of EngineeringBoard of AdvisorsCurrentAdvisory role

Board Governance

  • Committees and roles: Chair, Talent & Compensation Committee; Member, Audit Committee. The Audit Committee (4 meetings in 2024) oversees financial reporting, internal controls, conflicts, and related-party reviews. The Talent & Compensation Committee (5 meetings in 2024) oversees executive/director pay and equity plans.
  • Independence and leadership: Board determined McGuire is independent; Lead Independent Director role held by Nicolas Roelofs, Ph.D. since Aug 13, 2024.
  • Attendance: In 2024, each director attended at least 75% of board and applicable committee meetings (board held 5 meetings).
  • Interlocks: No compensation committee interlocks or insider participation in 2024.

Fixed Compensation

ComponentAmountNotes
Cash fees earned (FY2024)$67,500Actual cash earned by McGuire in FY2024
Annual Board retainer (policy)$42,500Retainer increased effective Feb 28, 2024
Compensation Committee Chair fee (policy)$15,000Chair retainer
Audit Committee member fee (policy)$10,000Member retainer

Performance Compensation

AwardGrant DateQuantityGrant-date Fair Value (USD)VestingNotes
RSU (Annual director grant)06/12/202458,178$108,793Vests in full on 06/12/2025Applies to non-employee directors (including McGuire)
Annual director awards (policy change effective 02/26/2025)n/a30,500 options + 20,500 RSUsn/aOptions/RSUs per policy; options 10-year term, FMV strikeNew outside director policy from 2/26/2025

Performance metrics table (directors):

Metric TypeDisclosure
Quantitative performance metrics tied to director equityNone disclosed; director equity vests time-based (annual RSUs; from 2025, a mix of options + RSUs). Change-in-control accelerates director awards per policy.

Change-in-control treatment (directors): Upon a change in control, outstanding director equity awards granted as a non-employee director accelerate vesting in full if the director remains in service through the transaction. Options are granted at FMV and have 10-year terms.

Other Directorships & Interlocks

CategoryDetail
Current public boardsInvivyd, Inc.
Current private/non-profitTectonic Therapeutic; Whitehead Institute
Former public boardsAcceleron, Alector, Arsanis, Cyclerion, Ironwood, Pulmatrix
InterlocksNone reported for compensation committee in 2024; no insider participation.

Expertise & Qualifications

  • Venture capital and corporate development expertise (Founding Partner, Polaris Partners), with seven prior years investing at Burr, Egan, Deleage & Co.
  • Academic credentials: B.S. Physics & Economics (Hobart), M.S. Engineering (Dartmouth Thayer), M.B.A. (Harvard Business School).
  • Seer board’s rationale: substantial corporate development and business strategy expertise gained in venture capital industry.

Equity Ownership

ItemDetail
Total beneficial ownership581,684 shares of Class A Common Stock (approx. 1.0% of Class A) and 4,088 shares of Class B Common Stock.
Breakdown (per footnote)Includes 244,370 Class A and 4,088 Class B held by Strong Bridge, LLC (McGuire as operating manager); 78,947 Class A held by Polaris Founders Capital Fund I, L.P. (McGuire is GP of managing member); 258,367 Class A options exercisable within 60 days (fully vested).
Unvested director equity (12/31/2024)RSU 58,178 scheduled to vest 06/12/2025.
Pledging/hedgingInsider trading policy governs directors; company policy prohibits executive hedging/pledging; no pledges disclosed for McGuire.
Ownership guidelinesNo stock ownership guidelines disclosed for named executive officers; no specific director ownership guidelines disclosed.

Governance Assessment

  • Board effectiveness and independence: McGuire is independent, chairs the compensation committee, and serves on audit—key oversight positions aligned with governance best practices. All directors met ≥75% attendance in 2024.
  • Compensation governance: Committee retains independent consultant (Aon) and uses peer benchmarking; shareholder say-on-pay support was ~83% at the 2023 annual meeting.
  • Director pay alignment: 2024 grants were time-based RSUs; from 2025, policy shifted to a mix of options and RSUs—potentially increasing alignment with long-term value creation.
  • Related-party/Conflicts: Other than legacy investors’ rights arrangements (IRA parties included entities affiliated with McGuire), the company disclosed no related-party transactions >$120,000 since Jan 1, 2023. The Audit Committee oversees conflict reviews.
  • RED FLAGS / Watch items: The board approved an option repricing in Oct 2024 for employees and named executive officers (not directors), citing retention and minimizing dilution; while common in down markets, repricing is often scrutinized by investors. The program included a premium exercise price if exercised before the retention period ends and did not change share counts or vesting schedules.

Overall: McGuire’s roles on Audit and as Comp Chair, independent status, and active governance processes (independent consultant, regular committee activity) support board effectiveness. No disclosed related-party transactions or pledging mitigate conflict risk. The 2024 option repricing (employee/NEO-focused) remains a governance sensitivity for investor monitoring.