Senseonics - Q4 2025
March 2, 2026
Transcript
Operator (participant)
Day everyone, welcome to Senseonics Q4 and full year 2025 earnings call. At this time, all participants are in a listen-only mode. Later, you will have the opportunity to ask questions during the question and answer session. Please note today's call will be recorded, and I'll be standing by should you need any assistance. It is now my pleasure to turn the conference over to Jeremy Feffer from LifeSci Advisors. Please go ahead.
Jeremy Feffer (Managing Director)
Thank you. This is Jeremy Feffer from LifeSci Advisors. Before we begin today, let me remind you that the company's remarks include forward-looking statements. These statements reflect management's expectations about future events, operating plans, regulatory matters, product enhancements, company performance, and other matters, and speak only as of the date hereof. These forward-looking statements involve a number of risks and uncertainties. A list of the factors that could cause actual results to be materially different from those expressed or implied by any of these forward-looking statements is detailed under Risk Factors and elsewhere in our annual report on Form 10-K for the year ended December 31, 2025, and our 10-Qs and our other reports filed with the SEC. These documents are available on the Investor Relations section of our website at www.senseonics.com.
We undertake no obligation to update publicly or revise these forward-looking statements for any reason except as required by law. Joining me today from Senseonics are Tim Goodnow, President and Chief Executive Officer, Rick Sullivan, Chief Financial Officer, and Brian Hansen, Chief Commercial Officer. Now I'll turn the call over to Tim.
Tim Goodnow (President and CEO)
Appreciate everyone joining us today. Looking back over 2025, it's hard to believe how much has changed at Senseonics. This time last year, Eversense 365 had only been available in the United States for a few months, and we were partnered with Ascensia Diabetes Care for all commercialization and sales operations globally. We were conducting feasibility studies for our Gemini product. On the financial front, our gross margins were hovering around 25%, annual revenue was less than $23 million, and we were in the process of executing a successful cost savings initiative to lower operating expenses. Today, just one year later, Senseonics is a fully integrated developer, manufacturer, and once again, seller of Eversense.
We have an exceptional sales and marketing team led by Brian Hansen, our new Chief Commercial Officer, and Eversense 365 is now approved in both the U.S. and in the European Union. In 2025, we achieved full year revenue of over $35 million, growing approximately 60% year-over-year. Our year-long sensor, our continued partnership with healthcare providers, and our enhanced direct-to-consumer marketing strategy has delivered tangible results with a doubling of patients on Eversense in the U.S., with new patient starts growing 103%. We have already accomplished margin improvements to greater than 50% to finish the year. 2025 was certainly a year of transformation at Senseonics. The strategic decisions we made last year established a strong foundation for growth in 2026 and beyond.
The biggest decision we made in 2025 was to transition all commercial activities from Ascensia Diabetes Care back to Senseonics, removing a layer of complexity from our operations and providing us with a new level of control and agility to execute on our focus strategy. By bringing the sales, customer service, marketing, and sales operations functions in-house, we both eliminate revenue sharing with Ascensia and have the opportunity to respond quickly to meet the needs of people with diabetes. This change also brings an impressive team of commercial professionals to Senseonics. This end-to-end responsibility for Eversense 365 unlocks operational efficiency, enhances our financial profile, enables more integration between our corporate objectives and commercial results. Additionally, this change simplifies revenue recognition and provides critical insights into the effectiveness of our DTC efforts.
PHC remains a meaningful shareholder in Senseonics and will continue to support the European commercialization of Eversense and under transition service agreements through the anticipated closing in Europe in the Q2 and establishment of our own in-country operations. To implement this commercial evolution and drive long-term revenue growth, Brian Hansen transitioned to Senseonics and brought with him his complete leadership and sales force team. Brian was formerly the head of Ascensia's CGM division and prior to that, the chief commercial officer for Tandem, bringing a tremendous amount of experience and expertise from his accomplished career in diabetes care.
In just a few minutes, I'll turn the call over to Brian so that he can give you a firsthand account of what has been a smooth and successful commercial transition. He'll also give his thoughts on our growth trajectory, which he will be instrumental in driving.
Excitedly, our integration with Sequr Med Tech's twiist Automated Insulin Delivery System was another significant milestone in 2025, not just for us, but for the diabetes community at large. Patients utilizing the twiist insulin pump can now use Eversense 365 to send glucose readings seamlessly to their pump for an entire year. This means eliminating a CGM change every 10-15 days and providing our type 1 patients with reliable and accurate glucose monitoring 365 days at a time. Our collaboration with Sequr Med Tech combines the world's most sophisticated glucose sensing, algorithm control, and pumping technologies, is just the first of many collaborations we hope to establish with pump partners. Finally, in 2025, we made improvements in our financials, raised capital from institutional investors and strategic partners, executed a reverse stock split, and began trading on the Nasdaq.
Similar to our other transformation initiatives, we believe these accomplishments set Senseonics up for long-term growth and disciplined financial execution. Moving on to the leading indicators for 2026. I'll start with a quick reminder that our business is seasonal. The Q4 is typically our strongest quarter due to insurance deductibles being met. Further, a higher number of existing customers are available for reorders of Eversense in the quarter because the U.S. commercial launch of Eversense 365 took place in the Q4 of 2024. Early adopters translate into annual reorders beginning in this Q4. Through this, we saw meaningful quarter-over-quarter growth for the entirety of 2025, including growth in leads, conversions, new patient starts, and prescribers of our sensor for the first time.
We expect this momentum to continue in 2026, buoyed by our growth initiatives and investments, the twiist integration, and expansion of Eversense into new markets. In January, we received CE marking for Eversense 365. We expect to launch 1 global product, Germany, Italy, Spain, and Sweden in the coming months with our own dedicated European sales force. We recognize that patients and providers in Europe have been waiting for us to deliver on our promise of one year, one CGM in their markets, and we now have the approval. We anticipate a similar uptake in interest in new patients on Eversense as we had in the United States. On the product pipeline front, we continue to advance development of both the Gemini and Freedom products.
We expect to complete the Gemini pivotal trials before the end of the year, with the launch expected to follow in 2027. Gemini improves on the capabilities of Eversense 365 with an integrated one-year battery and flash glucose monitoring capabilities without a transmitter. Freedom is close behind, with launch planned for 2028. The Freedom system further improves on Gemini, incorporating direct wireless communication between the sensor and the patient's phone. I'm confident that our decisions on execution in 2025 will form the foundation of our 2026 growth. We have the right team, the right financial structure, and the world's first and only year-long CGM to improve and simplify the lives of millions of patients worldwide. With that, I'll now turn the call over to Brian.
Brian Hansen (CCO)
Thanks, Tim, and hello to everybody on today's call. I would like to begin by expressing my excitement to be part of Senseonics and my gratitude to the U.S. commercial team that has transitioned to Senseonics from Ascensia. Here in the United States, the move was fairly straightforward, and we were very happy to see nearly 100% of the employees transition with us. We were also able to recognize a few synergies in the move, as well as shifting several roles around to better align our teams for success in the new year. The same effort is underway in Europe, where I expect the same result, and we have the launch of Eversense 365 right around the corner. More on that later.
As Tim mentioned, the strategic decisions taken in 2025 sets us up for continued success in 2026 and beyond.
Our direct consumer spend was a big growth driver for us in 2025, we will continue to invest heavily in that channel this year. It was clear with our revamped DTC campaign and enhanced spend that we could drive significant lead volume and leads drive awareness, patient interest, prescriptions, and ultimately new insertions translating into top-line revenue. There were multiple learnings from our work in 2025. Last year's back-end loaded DTC spend showed there is a sweet spot of investment for us. While we plan to spend a similar amount this year, roughly $12 million-$15 million, we will spend it a little more evenly over the entire year, building into the third and Q4. This should allow us to be more efficient with our resources, targeting higher quality opportunities, a higher close rate, and a lower cost per lead.
Another important initiative for 2026 is patient retention. While we are early in the renewals from our first patients on the Eversense 365 sensor, we are happy to report that patient retention is in line with our expectations. This is and will continue to become a more meaningful part of our business going forward. Programs put in place in 2025, as well as allocating resources to refine and enhance the patient journey with our product and our company, have positioned us nicely for the upcoming year. I would also like to express my gratitude to the legacy employees of Senseonics that have built such an amazing product. Not only does it last a full year as expected, its performance is unsurpassed.
We've also been working diligently to support the Sequr twiist Eversense 365 rollout and expect to see an increase in the Type 1 patients we serve as a result. As Tim mentioned, this collaboration enables us to combine two of the world's leading diabetes technologies to simplify life for patients requiring insulin. Anecdotally, I can tell you that from the team being at the Sequr annual sales meeting held earlier this month, we are both aligned and excited. Sequr has a large commercial presence in the United States.
I can confidently say that both teams have fully bought into this partnership. Now with Eversense 365 compatibility, Sequr is able to offer customers choice in selecting the continuous glucose monitor that works best for them. As a company, we more than doubled the number of Eversense users in the United States from 2024 to 2025.
For this year, our goal is to continue that momentum and double our patient base once again. We believe that we can accomplish this through successful renewal of our existing customers, driving new patient starts in the U.S. and abroad, and having pump integration which patients have requested for years. Acknowledging we are only a few weeks into the general availability of the combined offering, the results have exceeded my expectations. We have detailed the success of our DTC campaign from last year. Let's turn to our healthcare provider channel that continues to grow as well. The number of providers actively prescribing Eversense grew more than 80% year-over-year, reflecting broadening awareness and confidence in the 365-day system.
Access to the diabetes centers continues to grow. We look forward to working closely with the Sequr commercial team to expand our combined reach. We also saw continued expansion of the EonCare group, our in-house inserter network. We finished the year with approximately 60 providers performing nearly a quarter of all U.S. Eversense insertions. We will continue to add to this team in 2026, planning to end the year with approximately 100 providers driving an even greater percentage of the U.S. procedures. Turning to the European launch and transition for a moment, we are in the final stage of completing our European arrangements with Ascensia. Both companies' teams are collaborating well to smoothly transition the European CGM business.
Our team is working to establish the full organization we need in Europe, and we will utilize transition agreements with Ascensia in countries where we are currently building out our capabilities. Overall, we made great progress with the transition since the announcement in early September. Coming off our national sales meeting to unveil the new Senseonics, the team is energized and off to a good start to the year. This is a testament to our employees' hard work in getting here, their dedication, their belief in the product, as well as the potential future growth ahead of us. I'll now turn the call over to Rick to walk through the numbers.
Rick Sullivan (CFO)
Thanks, Brian. Thanks to everyone joining us this afternoon. Starting with the quarterly results. In the Q4 of 2025, net revenue grew 72% to $14.3 million, compared to $8.3 million in the prior year period on the continued strength of top-line Eversense 365 revenue. U.S. revenue for the Q4 was $12.1 million, and revenue outside the U.S. was $2.2 million. Importantly, in Q4 of 2025, we continued to recognize revenue through the collaboration agreement with Ascensia. We anticipate recognizing 100% of revenues going forward. We expect a similar channel mix going through our two primary sales channels in the U.S., direct shipments to DME distributors, and through bundled payment of the procedure and product, primarily through our consignment program.
Outside the U.S., we will sell both through tender agreements and to distributors, depending on the region. In Q4 2025, gross profit was $7.7 million, an increase of $3.7 million from the prior year period. This increase in gross profit was primarily driven by a full year of sales of Eversense 365, with more of our business going through our consignment sales channel, where we recognize 100% of the revenue and recorded a sales commission expense to Ascensia based on the current year's revenue sharing percentage. Research and development expenses in Q4 2025 were $8.8 million, a decrease of $0.6 million compared to the prior year period. The decrease was primarily due to the completion of the Eversense 365 system clinical trials and development efforts, as well as a reduction in headcount.
Q4 2025 selling, general, and administrative expenses were $19.8 million, an increase of $10.9 million compared to $8.9 million in the prior year period, primarily driven by higher selling and marketing personnel costs, promotional expenses mainly due to the DTC investments, sales commission expenses as our consignment program expanded, and other general and administrative costs, including transition costs incurred to support the commercial transition from Ascensia. Net loss was $20.8 million or a $0.46 loss per share in the Q4 of 2025, compared to a net loss of $15.5 million or a $0.40 loss per share in the Q4 of 2024. Net loss increased by $5.3 million, primarily due to increased sales commissions and other costs related to taking over the commercialization and distribution of Eversense.
For the full year, total revenue was $35.3 million compared to $22.5 million in 2024. U.S. revenue was $27.9 million in 2025 compared to $15.3 million in the prior year. The revenue outside the U.S. was $7.4 million in 2025 compared to $7.2 million in 2024. Net loss for 2025 was $69.1 million, a decrease of $78.6 million in 2024. The decrease in net loss was primarily driven by improved margins in our business from Eversense 365. Selling, general and administrative expenses for 2025 increased by $18.3 million year-over-year to $52.5 million. The increase was primarily driven by our direct-to-consumer campaign investments, sales commission expenses as we increased consignment sales, and costs related to the Ascensia transition.
Research and development expenses for 2025 decreased by $9.5 million from 2024 to $31.6 million. The decrease was primarily due to the completion of the Eversense 365 system clinical trials and development efforts, as well as a reduction in headcount. As of December 31st, 2025, cash, restricted cash, and cash equivalents totaled $94.3 million, and debt and accrued interest was $35.3 million. We expect full year 2026 global net revenue to be approximately $58 million-$62 million, representing year-over-year growth of 65%-76% as the company completes the transition of Eversense commercialization from Ascensia and brings the entire sales and marketing infrastructure in-house.
Due to the seasonality of our business, with deductibles resetting at the beginning of the year and higher utilization of patient assistance programs, we expect to receive the majority of our revenue in the second half of 2026, consistent with what we saw in 2025. Taking into consideration our margin performance to date, along with the planned launch of Eversense 365 in Europe, which will allow us to be on a single product globally, we expect full year 2026 gross profit margin to be greater than 50%, beginning slightly lower and increasing sequentially. We are excited to simplify our business model with the integration of the commercial organization and will recognize improvements in our top line and the expansion of our gross profit margins.
Due to the integration of the commercial organization and supporting transition service agreements from Ascensia, we expect operating expenses to increase by about $70 million, consistent with Ascensia's prior commercial spend. In 2026, we expect total operating expenses to be between $150 million and $160 million, with increases primarily in SG&A and a smaller increase in R&D for the Gemini pivotal trial. We expect cash utilization in 2026 to be between $110 million and $120 million, largely as a result increasing SG&A due to bringing the sales and marketing teams in-house. Last year, we expanded our debt facility with Hercules Capital up to $100 million, providing access for up to an additional $65 million of non-dilutive capital to help fund our increased operating expenses for the integrated business. With that, I'll turn it back to Tim.
Tim Goodnow (President and CEO)
Thank you, Rick. These are exciting times for Eversense. With the accelerating growth of our revolutionary 365-day product, we've delivered significant new patient additions and top-line growth across 2025, driven by expanding awareness and adoption of Eversense in the U.S. DTC investments continue to pay dividends as more people become aware of our compelling benefits of our product, and we now have access to a whole new population of patients following the launch of our first AID combination. Our margins are improving, and the sales force continues to gain traction with a productive and energized sales force post-transition. We are already seeing encouraging retention, with many early adopters now on their second year-long sensor, restarting the clock on 365 days of the best-in-class continuous glucose monitoring system.
In our exciting pipeline, the disruptive Gemini and Freedom programs are advancing, and we look forward to updating the market on continued progress in due course. Overall, this was a record-breaking year for Senseonics, but it's only just the beginning. Having demonstrated strong commercial progress, we have more confidence than ever in the clinical and commercial potential of Eversense. We also have the control of our destiny following the transition, with the right strategy in place and the right people leading the charge.
Thank you all for joining us today and for your continued support. We look forward to building on the momentum from the first year of Eversense 365 with another year of growth in 2026. I'll now turn the call over to the operator to answer any questions that you may have. Thanks once again for your time today.
Operator, let's go ahead and open up the call for questions.
Operator (participant)
Thank you. At this time, if you would like to ask a question, please press star one on your telephone keypad. To withdraw yourself from the queue, you may press star two. Once again, to ask a question, please press star one. We'll take our first question from Anthony Petrone with Mizuho Group. Your line is open.
Anthony Petrone (Managing Director Equity Research)
Thanks, and good afternoon, and congrats on a strong 2025 execution year. Maybe Tim, Rick, Brian, I'll start with perhaps some of the trends you're seeing here early in the year. You're coming off 2025, a 103% new patient starts for the year, hits a new high in the Q4. I know, Rick, obviously there's a little bit of seasonality on policy resets here as you start the year.
, anything you can provide just in terms of U.S. new starts at the beginning of the year, and then I'll have a couple of follow-ups.
Tim Goodnow (President and CEO)
Sure, Anthony. Thanks for the thanks for the question and time. We continue to do very nice on new patient starts. Three sixty-five product continues to form just as we expect excitedly. We're now into the more routine cycle of getting the reinsertions. New patient growth continues as as we've expected it to, as we planned it to. January typically is our softest month with the patient resets, but we plan for that. , very encouraging. We've seen a surprising amount of encouraging interest with the Sequr product and new patient starts associated with that. That's very encouraging to see. We continue we continue to make progress, as , with the CE marking for the three sixty-five in Europe.
We're looking for that region to really take off as well here later in 2026.
Anthony Petrone (Managing Director Equity Research)
Yeah. The follow-up is on that top-line guide, $58 million-$62 million. You have the U.S. clearance here earlier in this year as well as the twiist product launch February 19. To what extent in that range do you have some contribution for Europe and twiist? Maybe just a recap on twiist specifically, how the economics are split between Sequr and Senseonics. Thanks again. Congrats.
Tim Goodnow (President and CEO)
Sure. I'll let Rick speak to, speak to Europe. For me, from an economics perspective it's two companies that work together with from a marketing and awareness perspective, but the economics are unique to each company. We sell a sensor, we recognize the associated economics. They sell a pump, and then through the integration that the iCGM enables, the patient enjoys that combination. There's really no difference economically on a brand-new patient start that's on an MDI versus somebody that's on a Sequr pump.
Rick Sullivan (CFO)
For europe the past couple of years we've seen fairly consistent revenue in Europe, really expecting the growth with the 365-day launch in Q2. That along with the elimination of that revenue share to Ascensia, we do expect Europe to be about 20% of our revenue in 2026.
Anthony Petrone (Managing Director Equity Research)
Helpful. Thanks.
Operator (participant)
We'll move next to Josh Jennings with TD Cowen. Your line is open.
Josh Jennings (Managing Director)
Hi. Good afternoon. Thanks for taking the question. it's great to see that you're on track to double new patient starts in the patient base again this year. I was just wanting to check in on the takeover of the commercial organization in the United States and from Ascensia. Seems like it has been seamless. All the sales reps converted over under the Senseonics roof. Is it as seamless as it sound? Have there been any friction points?
Tim Goodnow (President and CEO)
Yeah. Josh, thanks for that. It's a good question. They're really as simple in the U.S. as it sound, it was as straightforward as we expected. They changed business cards, they got a new computer. They had to do a few things. We even pulled their cars over with them. Quite frankly, it went that simply. We have a full boat, and they all stayed. We're very fortunate. OUS, we have a little bit more work to do as we go through the transition here the first half of the year. We're hiring new folks to replace our BGM reps that were kind of supporting both products. OUS has a few moving parts to it differently than the U.S.
So far, the U.S., I mean, we had our kickoff meeting in January, late January in D.C., and everybody was there and excited and focused. Yeah, as I said in my comments, that one's gone very well. Knock on wood.
Josh Jennings (Managing Director)
Excellent. Do you mind just reviewing just where maybe some deficiencies were with Ascensia at the helm of the commercial effort? Was it investment levels in DCT? Was it aggressiveness in pursuing new prescribers? Just review how you guys are filling any voids that were in play prior to taking over the commercial effort in the U.S.
Tim Goodnow (President and CEO)
No, the strategic execution around the commercial activities really did hand over one for one, even in Europe. We had some opportunities in the operational part of the organization, for example, there were some quality, .
Rick Sullivan (CFO)
Duplication of effort.
Tim Goodnow (President and CEO)
Duplication that happened some strategy elements that happened. In those cases, we did do some rationalization. Obviously, since there was just a little bit of upstream marketing around product development that existed in the prior Senseonics organization, that's now been folded into the new Senseonics commercial team. , Brian and Rick and Ken, our GC, just really did an exemplary job just leading this transition. To be able to get every sales rep, every inside sales rep to go over and be part of Ascensia at 5:00 P.M. on Friday and show up at 8:00 A.M. on Monday as a Senseonics employee was really impressive, so. Absolutely 0, knock on wood, customer impact, through that transition. It's just been managed and executed with a great ability.
Josh Jennings (Managing Director)
Well, that's impressive. Just with the active prescriber base growing 80% last year. With Senseonics now in control of the commercial effort and the sales team, how do you expect that prescriber base to grow, one. Two, I mean, you guys are on track. Your guidance when the Sense was in control is the commercial effort was to double your patient base in 2025 and 2026 on the heels of the Eversense 365 launch with control now, complete control. I mean, could you do better than that? Could you see an acceleration in the prescriber base and new patient starts from this doubling, which is an impressive number, don't get me wrong, but.
Tim Goodnow (President and CEO)
Easy, Josh.
Josh Jennings (Managing Director)
I'll leave it there. Thanks for taking the questions.
Tim Goodnow (President and CEO)
Yeah, certainly it sounds like Brian's signing up for more than that. In all seriousness, obviously it's a significant push in 2025. , we did accelerate the DTC under the expectation, and I think we validated that perspective that this is really about awareness, right? As we spent the DTC, we made more and more patients who then in turn worked with their providers and made more and more providers aware of the opportunity with Eversense, the excitement around 365. For us to continue to sustain that level of growth, obviously, as Brian said, we are gonna spend a significant amount in DTC, but about the same that we spent last year. We just did back-end load it at the back half of the year.
The ramp is commensurate with that investment. We expect that ramp to slow down a little bit over the with the normalization of that spend over the year, but still supporting that that doubling of growth, or that approximately 70% of revenue growth across the across the whole company.
Josh Jennings (Managing Director)
Understood. That makes sense. Thanks for the answers.
Operator (participant)
We'll take our next question from Matt Miksic with Barclays. Your line is open.
Matt Miksic (Equity Research Analyst)
Great. Thanks so much for taking the questions. Congrats on the great progress and results. Maybe some follow-ups, lastly on the investment in DTC, is proved to be pretty successful last year. Within the spend this year, how are you thinking about it? Are you front-end loading it, back-end loading it? Has it just become sort of a reliable and important budget item? Just any color you can give us on the size or the direction of DTC spend would be great. I have a couple of quick follow-ups.
Brian Hansen (CCO)
Yeah. Brian here. We spread it out a little bit more this year. It was, again, as Tim said, more in that last six months, and we really put quite a bit in that September, October, November timeframe. That's when you wanna put a bunch in as the Q4 is so strong. We also really stressed our team by doing that. Now to kind of level load it a little bit more, spending not quite half in the first half of the year and then saving a little bit to push into that really important third and Q4 is how we're looking at it. We also learned a lot last year of what works and what doesn't work, what segments we were getting better returns versus others.
I think we're gonna do a much better job this year taking our same spend but maximizing it. Our team is right-sized for that as well right now. We're expecting to spend the same but get better results as we spread it out across the year. $12 billion-$15 billion is what we said in our prepared remarks.
Matt Miksic (Equity Research Analyst)
Okay. That's helpful. Then I guess the challenges or the sort of friction around getting more implanters up and running, getting more education out there, the DTC is part of that. , what do you see as the primary constraints right now in terms of growth, in terms of your ability to address new patient interests and new clinician interests? What are the things you're trying to address to kind of feed things and make the most of the opportunity you have? Then I have just one last question, if that's okay.
Tim Goodnow (President and CEO)
Yeah, sure. Sure. Number one, Matt, it continues to be, as I said, it's around awareness, that's where the DTC really helped. That drove it from the consumer level. we we would certainly augment that with a strong internal team that takes the inbound interest, does the facilitation, the adjudication the communication of the e-economics. Frankly, does work with the outside sales team, which also plays a very big role in the awareness on the clinical side, on the professional. We're gonna continue to do that. We have 45 regions right now that are focused in the primary areas. They are working hard to not only expand their reach but also to go deeper within the clinics.
We think that's an opportunity as well, to make sure that instead of oneor two doctors in a clinic being heavy prescribers, we're gonna turn that into three, four, five prescribers. Number one is certainly about awareness. Number two from insertion, you're absolutely right. We're gonna continue to focus on it. That said, recall that our Eon Care is a major initiative for us, right? We ended the year just about 60 nurse folks that were contracted with us to do the insertions, and we are absolutely on target here as we are now two months into it to end the year at 100 nurses. We anticipate they'll be doing 30%-35% of all of our insertions in that time period. A lot of organic growth through that support initiative as well. Okay.
Just finally.
Brian Hansen (CCO)
I would just add one thing to it. It's.
Tim Goodnow (President and CEO)
Go ahead. Sorry.
Brian Hansen (CCO)
No, just we saw a lot of changes in reimbursement last year, going from 180 to 365. Certainly the first three, four months of the year, we had some things to work through. We revamped that team. We've seen quite a few good results from that and really getting a clearer picture of reimbursement, make it easier for the physician and the patient to know exactly how this is all gonna work. As Tim said, the insertion and reimbursement piece, we've come a long way over the last 12 months of that. We really believe we'll benefit from that here in 2026. We're becoming easier to work with, and the volume has certainly helped with that.
Tim Goodnow (President and CEO)
Matt, you'll recall there was a little bit of a hurdle in early 2025 with the Physician Fee Schedule. They first came out with G codes.
Brian Hansen (CCO)
Yep.
Tim Goodnow (President and CEO)
Transitioned to the standard CPT codes. We don't have that this year, right? They've republished the results or published the results for 2026. That started right away we've been into the economics and implementation of those right from the very beginning of this year.
Matt Miksic (Equity Research Analyst)
That's great. Then just lastly, just on the type of new folks signing up new users, experienced users, where they're coming from, the reasons, I mean, there's lots of reasons why they might choose to choose Eversense. What are some of the?
Tim Goodnow (President and CEO)
Yeah, I'll let Brian speak.
Matt Miksic (Equity Research Analyst)
Major reasons. Yeah, and maybe how that's changing.
Tim Goodnow (President and CEO)
I'll let Brian speak to the-
Matt Miksic (Equity Research Analyst)
If at all, how it's changing. Thanks so much.
Tim Goodnow (President and CEO)
Yeah. Matt, I'll let Brian speak to the change, which we're absolutely seeing now with an AID partner. From a from an investment perspective, much of our DTC and quite frankly, the fast style nature of the buy and bill, really makes this attractive product for people that are on Medicare. , we have transitioned to probably 70% type 2 patients in 2025, or at least coming out of 2025. I expect that that proportion will actually change back more towards type 1 now here with the pump partner. We continue to see the majority of our patients are switchers that really are coming from one of the two transcutaneous sensors, with about 15% or 20% are brand new to the space.
Brian Hansen (CCO)
Yep.
Tim Goodnow (President and CEO)
Is that about right? On the new pump rollout has been very encouraging.
Matt Miksic (Equity Research Analyst)
That's great. Thank you.
Brian Hansen (CCO)
Not much more to add there, Tim. Spot on.
Operator (participant)
We'll take our next question from Marie Thibault with BTIG. Your line is open.
Marie Thibault (Managing Director)
Hi. Good evening. Thanks for taking the questions. Nice job on this quarter for sure. Wanted to ask a follow-up here on the EonCare inserter network. You mentioned moving from 60 to 100 this year. What's sort of the gating factor on expanding that more quickly? I know they're doing about a quarter of volumes. It seems like you could move to a third or better of volume. I guess what challenges, if any, are there in kind of expanding that network and moving more quickly on that opportunity?
Brian Hansen (CCO)
Yeah, Marie, there really isn't. It's really about volume and having enough work for them. There's really no downside to going to 125 or 150. If the volume justifies it, we can keep them busy, and we can identify folks in the areas where we need them. That 100 mark seems like a sweet spot. getting an increase in the % of insertions that they do is good for everybody, our economics as well as the quality of the work. It frees up the physicians in the prescriber-only areas where they really don't wanna do it. That's kind of a goal, but it could exceed that. There's nothing that stops us from doing more.
We just need to have the volume to keep them busy and justify putting those in places and getting them accredited and certified and trained. It's a good question. There really is no barrier.
Marie Thibault (Managing Director)
Okay, good to hear. As a follow-up, on the operating spend level that you discussed, I think $150 million-$160 million this year. Understand that the bulk of that is kind of picking up where Ascensia left off in terms of the spend. Maybe we can sort of get longer term and understand, are you expecting a multi-year investment here? Should we expect continued step-ups in the out years? Certainly just wanna understand it now that everything's under the Senseonics roof, if you will. Thank you for taking the questions.
Rick Sullivan (CFO)
From the commercial spend perspective, it'll certainly continue to grow as our revenue grows, but not at the magnitude that it is in 2026. It will be more efficient, but as we launch new products, we'll expand the number of territories, increase the number of providers from the [Foreign Language]. Again, it'll decrease as a percentage of revenue going forward. This year we do have a Gemini clinical trial, which is about $5 million of an increase in our R&D line. We'll see a similar amount next year for the Freedom trial. R&D should go down for further out years.
Marie Thibault (Managing Director)
All right. Helpful detail. Thank you, Rick.
Rick Sullivan (CFO)
Yep.
Operator (participant)
We'll move next to Jonathan Block with Stifel. Your line is open.
Jonathan Block (Managing Director)
Great. Thanks, guys. Good afternoon. Tim or Brian, anything around the timing of additional pump partnerships coming on board? , do you expect that in 2026? , Rick, does the guidance arguably take into account any thoughts or additional pump partnerships this year?
Tim Goodnow (President and CEO)
Thanks, John. We do continue to work with the additional pump opportunities. We're not yet announcing any of those or going public with them. , we do have quite a bit of interest. Obviously, getting the first one out has creates a little bit of dynamic of there's only one pump company right now that has access to the Eversense, and they've seen an encouraging conversion as a result of that. We certainly expect that's gonna work in our favor. We have not, as of yet, modeled additional pump companies in. We would look for that to be upsides, but still not announcing timing on the next one yet.
Jonathan Block (Managing Director)
Okay. Thanks for that. I'll just try to get a little bit more granular on the revenue. rick you provided some details on the cadence. It was more, I believe, what you alluded to, call it like H2 '2026 versus H1. Any more details you can give, just even call it Q1 due to some of the moving parts with Ascensia. When I look at straight around $10 million and those moving parts, and here we are in early March, is that sort of a good figure to call it set ourselves and then think about the other commentary you provided, H2 versus H1? Thank you.
Tim Goodnow (President and CEO)
Yeah. From a revenue perspective, we know that we have the seasonality in Q1 with the deductibles resetting and higher utilization of our patient assistance programs, which impacts that ASP through that channel. Then also the second half of the year is typically where we have now some large of our renewals from the past couple of years with the 365 launch. The revenue is certainly back half loaded, and I do expect it to be similar to 2025, thinking about 40% in the first half, 60% in the second half, approximately. We will see certainly a step down in Q1 because of that seasonality from where we were in Q4.
Jonathan Block (Managing Director)
Okay, great. I'll follow up with you guys offline. Appreciate it.
Operator (participant)
We'll move next to Ben Haynor with Lake Street Capital Markets. Your line is open.
Ben Haynor (Managing Director)
Good afternoon, gentlemen. Thanks for taking the questions. First off, for me, on the DTC marketing, what sort of lessons are you learning there? are for instance, areas where you have more users, do you see a greater impact from advertising? Does greater awareness in a given area kinda translate to cheaper user acquisition? How should we think about some of the dynamics of the DTC marketing?
Brian Hansen (CCO)
Yeah, we could talk about that for hours. The first and foremost is we tend to really focus where we have qualified inserters. We've played with that geography boundary. We can geo-fence our spend. It's very interesting when you start moving it 75, 100, 125 miles, how you start to reduce the effectiveness of it when you get too far away from an inserter. To Marie's question earlier of getting more insertion areas and coverage really helps us then maximize our DTC efforts going forward. You get into the different channels, you get into the different markets that you try to pour a little bit more into. It typically success breeds success there.
We watch that very closely when we see areas that we get a better return, lower cost per workable lead, all the things that we follow very well. We continue to pour more in until we see it diminish at that point. We certainly test a whole bunch of different ads and methods that we go through. The team is constantly changing those almost on a week or two-week basis in different markets at times as well. The sophistication is very, very interesting. What we found last year is we did fairly well, especially with the robust Medicare reimbursement we had. We really started to lean into some of those areas, and again, where we had proper coverage for insertions.
I could go on and on the different levers we pull, but you really do start to lean into those areas you're doing very well and continue to invest more and more in those until you see it start to slow down a little bit. That's some of the learnings we really got from last year and will continue this year. I think we've got a more focused effort as we go into 2026.
Ben Haynor (Managing Director)
Great. That's helpful color. Then are you seeing any changes to kind of the behavior of new prescribers with the 365-day version?
Tim Goodnow (President and CEO)
No, I wouldn't say there's been a change in behavior, certainly at this level.
Ben Haynor (Managing Director)
Right.
Tim Goodnow (President and CEO)
The recognition and now the feedback it's much more common to see feedback from users now that are gone on to their second sensor. , the retention rates are encouraging, right? People love the product, when they when they use it for as long as a year, it becomes part of their life, right? I would say from that perspective a convert is very, very attractive to us. From a new patient perspective I don't think we see any real behavior differences from as we've seen before, nor from the prescriber side.
Ben Haynor (Managing Director)
Okay. Got it. On that retention comment, can you remind us kind of where the expectations are for retention and that are being exceeded?
Tim Goodnow (President and CEO)
Yeah. we we haven't updated those as yet as we're still honestly pretty early into the one-year renewal cycle. Our history had been from first to second sensor, it was in the 70s. Second to third sensor was in the 80%. By the time people were on the third sensor, it was 90% retention or sometimes even higher, as is evidenced in our European market. I would anticipate that the largest drop-off is from first to second, but still some pretty attractive rates.
Ben Haynor (Managing Director)
Got it. Thank you for the call, gentlemen, and congrats on the progress.
Tim Goodnow (President and CEO)
Thank you.
Thanks.
Operator (participant)
Once more, that is star one for your questions. We'll move next to Sean Lee with H.C. Wainwright. Your line is opened.
Sean Lee (VP of Equity Research)
Good afternoon, guys, thanks for taking our questions. Just have two of them. First, for the European market, what's the expected timeline for the rollout there? Are you seeing any hurdles from the transition, especially as some of these are affected by local purchase agreements?
Tim Goodnow (President and CEO)
Yeah. The timing is consistent as we've guided since the beginning of the year. That being, we expect the transition to occur in the Q2. That is gated by the transitions that we're going through right now. Many of these markets are tender markets, they're contracted with Ascensia, and we are transitioning those to Senseonics. We're in that process right now. We did receive the approval, the CE mark we have the authorization to go, and we'd anticipate mid-Q2 that we'll be rolling out the product into those markets. Some of the tenders will go frankly go through the summer or even into early fall, depending on the contracts that we have.
Say say May through September, October time period, we'll transition.
Sean Lee (VP of Equity Research)
Great. Thank you for the clarity on that. My second question is on the Gemini study and how the potential approval would go for that. I was just wondering, is the FDA requiring a second MARD for the flash mode for the Gemini because it has both two different functionalities versus Eversense 365? How does the inclusion of the dual modality impact the complexity of the trial?
Tim Goodnow (President and CEO)
Yeah. The FDA will expect that in the, in the flash mode or in the near-field mode with the transmitter, it will give you the same result. The expectation is it's the same chemistry, the same sensor. Our expectation and their expectation should be that it's iCGM compliant. As you recall, our MARDis around 8% that supports that, and we don't have any reason to expect that that would change. Technologically, there should be no reason why you get a different result in flash or with near-field.
Sean Lee (VP of Equity Research)
Got it. Fantastic. That's all I have. Thanks for taking our questions.
Tim Goodnow (President and CEO)
Great. Thanks, Sean.
Operator (participant)
Thank you. This does conclude our question and answer session and today's conference. You may now disconnect your lines. Thank you for your time, and have a great day. Goodbye.