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Daniel Long

Senior Vice President, Drug Discovery at Septerna
Executive

About Daniel Long

Daniel Long, D.Phil., is Senior Vice President, Drug Discovery at Septerna, serving in this role since December 2021; he joined the company in October 2021. He is 52 years old and holds a B.A., M.A., and D.Phil. in Chemistry from the University of Oxford, with an industrial post-doctoral fellowship at DuPont Pharmaceuticals . Prior to Septerna, he spent over 20 years at Theravance Biopharma, rising to Vice President and Head of Medicinal Chemistry, Biology and Pharmacology . As an emerging growth company, Septerna has not provided TSR or revenue/EBITDA growth metrics linked to executive pay, and it is not required to conduct say-on-pay votes at this time .

Past Roles

OrganizationRoleYearsStrategic Impact
Septerna, Inc.Senior Vice President, Drug DiscoveryDec 2021–presentLeads drug discovery; deep GPCR expertise applied to pipeline programs .
Theravance Biopharma, Inc.VP, Head of Medicinal Chemistry, Biology & Pharmacology; prior scientist roles2001–2021Led multidisciplinary discovery functions; extensive small-molecule and respiratory disease experience .
DuPont PharmaceuticalsIndustrial post-doctoral fellowNot disclosedIndustry-focused training; foundation for medicinal chemistry career .

External Roles

No public company directorships or external board roles disclosed for Daniel Long .

Fixed Compensation

2023 pay (last year where Long is a disclosed named executive officer):

Metric2023
Base Salary ($)$369,357
Target Bonus (%)30% of base salary
Actual Bonus Paid ($)$149,590 (discretionary annual bonus)
Sign-on Bonus ($)$62,500 (second tranche of a $125,000 sign-on)

Notes:

  • Bonuses were based on corporate objectives; see Performance Compensation below .

Performance Compensation

Annual cash incentive (2023):

Metric CategoryWeightingTargetActual AchievementPayout FactorVesting
Corporate performance objectives (program, platform, finance/business development)Not disclosed100%135% of target achieved135% factor applied to eligible bonus Cash (no vesting)

Long-term equity (2023 grants and outstanding at year-end shown in next section).

Equity Ownership & Alignment

Beneficial ownership (pre-IPO snapshot at Aug 31, 2024):

ItemShares% of Outstanding
Total beneficial ownership101,040* (<1%)
Composition detail92,911 common (incl. unvested restricted); 8,129 options exercisable within 60 days

Outstanding equity awards (as of Dec 31, 2023):

Grant DateVesting CommencementOptions Exercisable (#)Options Unexercisable (#)Exercise Price ($)ExpirationUnvested Restricted Shares (#)Vesting Schedule
11/12/20238/1/20231,742 19,163 2.76 11/11/2033 Options vest in 48 equal monthly installments over 4 years
10/26/202111/2/202146,456 Vesting footnote referenced in filing; schedule not specified in accessible text

Trading, hedging, pledging, and alignment safeguards:

  • Insider trading policy prohibits short sales, derivatives, and any hedging or pledging of company stock by executives and directors .
  • Rule 10b5-1 plan policy is in place for pre-arranged trades when not in possession of MNPI .
  • Compensation recovery (clawback) policy compliant with SEC/Nasdaq: recoup incentive-based compensation for restatements within prior 3 years .

Employment Terms

TermDetails
Employment start and roleOffer letter dated Sept 27, 2021; start Oct 4, 2021; SVP, Drug Discovery .
Employment natureAt-will; eligible for standard benefits .
Sign-on incentivesRestricted stock award; $125,000 sign-on paid in two $62,500 tranches (Jan 2022 and Jan 2023) contingent on continued employment through payment dates .
Executive Severance Plan (adopted Oct 2024)Double-trigger change-in-control benefits: CEO 18 months base + 1.5x target bonus and full acceleration of time-based equity; Tier 2 executives (includes COO and CMO) 12 months base + 1.0x target; Tier 3 executives 9 months base + 0.75x target; COBRA contributions; 280G cutback (no gross-up). Plan tiers for other executives are determined by the plan administrator; Long’s tier not disclosed .
Policies and governanceClawback policy; prohibition on hedging/pledging; Rule 10b5-1 plans permitted; emerging growth company—no required say-on-pay vote .

Compensation Committee Analysis

  • Compensation committee (independent directors) oversees pay and approves compensation for employees at or above Senior Vice President, including equity grants and award agreements .
  • Pearl Meyer retained in 2024 as external compensation consultant; assisted in developing peer companies and benchmarking executive and director compensation; no conflicts identified .

Performance & Track Record

  • Biography emphasizes >20 years of discovery leadership at Theravance before joining Septerna; at Septerna, leads drug discovery in GPCR-focused programs. No company-wide TSR or revenue/EBITDA performance metrics tied specifically to Long’s pay are disclosed .

Investment Implications

  • Pay-for-performance: Long’s 2023 bonus was fully tied to corporate objectives and paid at 135% of target, indicating incentives aligned to program/platform and BD milestones rather than purely financial KPIs .
  • Retention and selling pressure: Meaningful unvested restricted stock (46,456 shares) and time-based option vesting over 48 months create ongoing retention hooks; hedging/pledging prohibitions and availability of Rule 10b5-1 plans reduce governance risk around trades but scheduled vesting may add supply over time .
  • Change-in-control economics: Company-wide executive plan provides double-trigger severance and full acceleration for time-based equity; performance award treatment per award agreement; no tax gross-up (280G cutback), which is shareholder-friendly. Long’s specific tier is not disclosed, so cash multiple unknown .
  • Ownership alignment: Pre-IPO beneficial stake <1%, with mix of unvested RS and options; alignment further supported by clawback and anti-hedging policies .