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Shalini Sharp

Director at Septerna
Board

About Shalini Sharp

Independent Class II director (age 50) at Septerna, Inc. since January 18, 2024; term expires at the 2026 annual meeting . Harvard College BA and Harvard Business School MBA; former EVP/CFO at Ultragenyx and CFO at Agenus; designated “audit committee financial expert” and chairs Septerna’s Audit Committee . The board determined she is independent under Nasdaq/SEC rules; she attended ≥75% of board and committee meetings in 2024 .

Past Roles

OrganizationRoleTenureCommittees/Impact
Ultragenyx Pharmaceuticals (RARE)EVP & CFOMay 2012 – Oct 2020 Led finance at commercial-stage biotech; capital markets and scaling
Agenus (AGEN)Finance roles incl. CFO; DirectorAug 2003 – May 2012; Board May 2012 – Jun 2018 Finance leadership; board oversight in immuno-oncology
Elan PharmaceuticalsEarlier careerNot disclosed Strategy/finance exposure
McKinsey & CompanyEarlier careerNot disclosed Consulting, strategic problem solving
Goldman SachsEarlier careerNot disclosed Capital markets experience

External Roles

CompanyTickerRoleTenure
BeiGene, Ltd.BGNEDirectorCurrent
Neurocrine Biosciences, Inc.NBIXDirectorCurrent
Organon & Co.OGNDirectorCurrent
Mirati Therapeutics, Inc. (acquired by BMY)DirectorMar 2021 – Jan 2024
Sutro Biopharma, Inc.STRODirectorNov 2018 – Nov 2023
Precision BioSciences, Inc.DTILDirectorDec 2018 – Jun 2022
Panacea Acquisition Corp.PANADirectorJun 2020 – Feb 2021

Board Governance

  • Committees: Audit (Chair), Compensation (Member); not on Nominating & Governance .
  • Independence: The board determined all non-employee directors except Dr. Ezekowitz are independent; Ms. Sharp is independent .
  • Attendance: The board met 17 times in 2024; each incumbent director attended ≥75% of board and relevant committee meetings .
  • Audit oversight: Audit Committee met once in 2024; Ms. Sharp signed the Audit Committee Report recommending inclusion of audited 2024 financials in the 10-K and is designated the audit committee financial expert .

Fixed Compensation

ComponentAmount/TermsSource/Date
Fees earned (cash) in 2024$34,492 2024 actual
Non-Employee Director Policy: Board annual retainer$40,000; effective at IPO Policy adopted at IPO
Additional retainer: Non-executive chair$30,000 Policy
Committee retainers – AuditChair $15,000; Member $7,500 Policy
Committee retainers – CompensationChair $12,000; Member $6,000 Policy
Committee retainers – Nominating & GovernanceChair $10,000; Member $5,000 Policy
Pre-IPO director engagement letter (cash)Annual cash retainer $30,000, payable quarterly Engagement letter

Performance Compensation

AwardGrant dateShares/UnitsExercise PriceVestingPerformance Metrics/Conditions
Director Initial Grant (on joining)Jan 18, 202429,034 options Not disclosed16 equal quarterly installments over 4 years; full acceleration on “sale event” Time-based; sale-event acceleration
Additional Director OptionsMar 20249,871 options $2.76 1/16th quarterly from Mar 1, 2024; sale-event acceleration Time-based; sale-event acceleration
Director Options (pre-IPO grant)Sep 202413,356 options $6.81 1/16th quarterly starting at IPO effective date; sale-event acceleration Dual-condition: service-based and performance-based tied to IPO or sale
Director Annual Grant (post-IPO policy)Jun 17, 202516,623 options$10.24Vests in full by next annual meeting or first anniversary, subject to service; expires in 10 years (per policy) Annual grant under policy; Form 4 award on 6/17/2025

Director Compensation (2024 mix)

Component2024 AmountNotes
Cash fees$34,492 Audit chair/member and compensation member service in 2024
Option awards (grant-date fair value)$244,421 ASC 718 fair value; includes pre-IPO options; not economic value realized
Total$278,914 2024 director compensation total

Other Directorships & Interlocks

Interlock/OverlapDetailsImplication
Shared board (Organon)Ms. Sharp and Septerna director Dr. Alan Ezekowitz both serve on Organon’s board Potential information flow and network benefits; monitor for any business dealings to avoid conflicts; none disclosed with Organon

Expertise & Qualifications

  • Financial leadership: EVP/CFO (Ultragenyx), CFO roles at Agenus; capital markets and scaling experience .
  • Designated audit committee financial expert by Septerna’s board .
  • Education: Harvard College (BA), Harvard Business School (MBA) .
  • Multi-company board experience across biopharma (BeiGene, Neurocrine, Organon) .

Equity Ownership

MeasureValueComposition/Notes
Beneficial ownership (as of Apr 21, 2025)13,826 shares; <1% of outstanding Options exercisable within 60 days of Apr 21, 2025
Total options held (as of Dec 31, 2024)52,261 options Sum of: 29,034 initial director grant + 9,871 Mar 2024 grant + 13,356 Sep 2024 grant
Hedging/PledgingProhibited for directors under insider trading policy No pledging allowed; 10b5-1 plans permitted under policy
Ownership guidelinesNot disclosed

Insider Trades (Form 4)

Filing DateTransaction DateTypeSecurityQuantityPricePost-Transaction OwnershipURL
2025-06-202025-06-17A (Award)Stock Option (Right to Buy)16,623$10.2416,623https://www.sec.gov/Archives/edgar/data/1984086/000095017025088622/0000950170-25-088622-index.htm

Governance Assessment

  • Strengths:

    • Independent director with deep finance background; audit chair and designated financial expert improve oversight of reporting, controls, and risk management .
    • Attendance threshold met (≥75%); committee leadership and signed audit report indicate active engagement .
    • Clear policies on clawbacks (executive incentive recovery), hedging/pledging prohibitions, and related-party reviews through Audit Committee reduce governance risk .
  • Watch items:

    • Multiple concurrent public boards (BGNE, NBIX, OGN) could create time/attention constraints; monitor attendance/engagement in future disclosures .
    • Interlock at Organon with another Septerna director (Dr. Ezekowitz) requires ongoing conflict screening; no related-party transactions disclosed involving Ms. Sharp .
    • Director equity awards include sale/IPO-related acceleration; while typical pre-IPO, ensure alignment post-IPO via annual grants governed by policy rather than transactional triggers .
  • Compensation alignment:

    • 2024 mix skewed toward options ($244k grant-date fair value vs. $34k cash), consistent with early-stage biotech governance and alignment with shareholder outcomes; post-IPO policy standardizes cash retainers and annual option grants .