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Tyvin Rich

Chief Clinical Officer at Shuttle Pharmaceuticals Holdings
Executive

About Tyvin Rich

Tyvin A. Rich, M.D. is SHPH’s Chief Medical Officer responsible for clinical development of radiation sensitizers, with a career spanning leadership roles at MD Anderson (Director of Clinics), University of Virginia (Professor and Chairman), and current practice at Hampton University Proton Therapy Institute; he holds degrees from Rutgers (undergraduate) and University of Virginia (MD), with residencies at Georgetown (internal medicine) and Massachusetts General Hospital/Harvard (radiation therapy), and has authored 200+ publications and chaired RTOG protocols advancing chemoradiation in GI cancers . As of the FY2023 10-K, Dr. Rich’s age was disclosed as 76 and his title as Chief Clinical Officer; the FY2024 10-K references him as Chief Medical Officer with the same scope . His employment agreement (May 31, 2019) sets base salary and milestone-based bonus parameters and an RSU grant vesting over three years, with Good Reason severance equal to 12 months of base salary . In May 2025, SHPH implemented a 70% salary reduction for salaried employees and executive officers, including Dr. Rich, indicative of near-term cash preservation measures .

Past Roles

OrganizationRoleYearsStrategic Impact
University of Texas M.D. Anderson Cancer CenterProfessor of Radiotherapy; Director of Clinics1984–1995Led clinical operations; foundation for expertise in chemoradiation; authored significant research output .
University of Virginia Health Sciences CenterProfessor and Chairman, Therapeutic Radiology & Oncology1995–2010Chaired department; advanced chemoradiation protocols; chaired RTOG trials in rectal/pancreatic cancers .

External Roles

OrganizationRoleYearsStrategic Impact
Hampton University Proton Therapy Institute (HUPTI)Staff Radiation Oncologist2010–presentClinical practice in proton therapy; oversight relevant to radiation sensitizer development .
University of VirginiaProfessor Emeritus, Radiation Oncology2010–presentOngoing academic contributions; recognized authority in GI chemoradiation .

Fixed Compensation

MetricFY 2022FY 2023FY 2024
Base Salary ($)$67,077 $220,226 $218,000
Target Bonus ($)$43,000 (per employment agreement) $43,000 (per employment agreement) $43,000 (per employment agreement)
Actual Bonus Paid ($)$0 (not listed for 2022) $43,000 $0
Temporary Salary ReductionN/AN/A70% salary reduction effective May 21, 2025 (post-FY)

Performance Compensation

Incentive TypeMetricWeightingTargetActual/PayoutVesting/Timing
Annual Cash BonusMilestone-based (specific KPIs not disclosed)Not disclosed Not disclosed $43,000 paid in 2023; none in 2024 Annual, based on milestone achievement (narrative only) .
RSUs (Initial grant)Time-based vestingN/A3,843 RSUs granted 5/31/2019 Grant value not quantified beyond share countVested in three equal annual tranches on each anniversary of 5/31/2019 (i.e., 2020/2021/2022) .

Notes:

  • Proxy and 10-K disclosures reference “milestones” for bonuses but do not publish revenue/EBITDA/TSR targets or weightings for Dr. Rich .

Equity Ownership & Alignment

Metric2022202320242025
Beneficial Ownership (shares)3,843 2,429 2,429 304
Ownership % of Outstanding<1% (“-” denotes <1%) <1% (“-” denotes <1%) <1% (“-” denotes <1%) <1% (“-” denotes <1%)
Shares Outstanding (context)15,984,125 (as of Oct 19, 2023) 15,984,125 (table context) 16,794,893 (as of Jun 4, 2024) 6,257,693 (as of Mar 13, 2025)
Pledged/Hedged SharesNot disclosed Not disclosed Not disclosed Not disclosed
Stock Ownership GuidelinesNot disclosed Not disclosed Not disclosed Not disclosed

Employment Terms

TermDetail
Employment Agreement DateMay 31, 2019
TitleChief Clinical Officer (earlier proxies); Chief Medical Officer (FY2024 10-K)
Base Salary$218,000 per year (agreement)
Target Bonus$43,000 (milestone-based)
RSU Grant3,843 RSUs; vesting in three equal annual installments on each anniversary of grant
Severance (Good Reason)12 months of then-applicable base salary, subject to compliance
Change-of-ControlNot disclosed (no single/double-trigger terms disclosed)
Clawback/Ownership/Hedging PoliciesNot disclosed for Dr. Rich specifically
2025 Compensation Action70% salary reduction implemented May 21, 2025 for salaried employees and executive officers, including Dr. Rich

Say-on-Pay & Shareholder Feedback

  • 2025 Annual Meeting advisory vote on executive compensation (“Say on Pay”): For 2,542,575; Against 469,312; Abstentions 87,730; Broker Non-Votes 1,078,407 — advisory approval .
  • 2025 meeting quorum: 4,178,024 shares represented (~66.8% of outstanding); shares outstanding 6,257,693 as of record date .

Compensation Structure Analysis

  • Mix shifted toward fixed cash with minimal variable payouts: Dr. Rich received salary-only compensation in 2024 ($218,000) and a modest bonus in 2023 ($43,000), with earlier compensation including stock awards in 2021–2022, indicating lower current at-risk pay linkage .
  • Milestone-based bonus framework lacks published financial/TSR metrics and weightings, limiting transparency into pay-for-performance alignment for Dr. Rich .
  • Temporary 70% salary reduction in May 2025 suggests near-term liquidity management and could increase retention risk for executives tied primarily to cash comp .

Performance & Track Record

  • Scientific and clinical leadership: Chair of RTOG protocols advancing chemoradiation in rectal and pancreatic cancers; >200 publications, reviews, book chapters — supports domain expertise for SHPH’s radiation sensitizer programs .
  • Long-tenured academic and clinical roles at premier institutions (MD Anderson, UVA, HUPTI) establish execution capability in oncology trials .

Investment Implications

  • Alignment: Dr. Rich’s beneficial ownership is small (<1% across 2022–2025) with legacy RSU grants fully vesting by 2022; current equity-based incentives for Dr. Rich are not disclosed beyond the 2019 grant, limiting ongoing equity alignment signals .
  • Pay-for-performance: Bonus structure references “milestones” but lacks disclosed financial/operational targets and weightings; 2024 bonus at $0 and 2023 at $43,000 implies limited variable compensation, reducing immediate trading signal value from incentive payouts .
  • Retention risk: The company-wide 70% salary reduction (May 2025) elevates near-term retention and focus risk for key leaders reliant on cash compensation, especially if equity refresh or retention grants are not provided or disclosed .
  • Governance sentiment: 2025 say-on-pay received majority “For” votes (2.54M vs. 0.47M), indicating shareholder tolerance of current compensation practices, though the lack of metric disclosure could become a focus if performance or liquidity concerns persist .

Data gaps for deeper analysis:

  • No disclosure of current RSU/PSU grants, vesting schedules, or performance metrics for Dr. Rich beyond the 2019 agreement.
  • No pledging/hedging policy disclosure specific to Dr. Rich; no Form 4 trading pattern analysis provided here.

Sources: Company DEF 14A (2022, 2023, 2024, 2025), 10-K FY2023/FY2024, and relevant 8-K filings .