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Joshua Resnick

Director at Sionna Therapeutics
Board

About Joshua Resnick

Joshua Resnick, M.D., M.B.A., age 50, has served as an independent Class I director of Sionna Therapeutics since December 2019 and was re‑elected at the June 12, 2025 annual meeting for a term through 2028 . He is Senior Managing Director at RA Capital Management, a faculty member at Harvard Medical School, and an attending physician in Emergency Medicine at Massachusetts General Hospital; he holds a B.A. (Williams), M.D. (UPenn Perelman), and M.B.A. (Wharton) . The board determined all directors other than the CEO are independent under Nasdaq and SEC rules, which includes Dr. Resnick .

Past Roles

OrganizationRoleTenureCommittees/Impact
RA Capital Management, L.P.Managing DirectorOct 2018 – Mar 2023Investor/operator experience cited as key board skill

External Roles

OrganizationRoleTenure/StatusNotes
RA Capital Management, L.P.Senior Managing DirectorCurrentInvestor and industry experience
Harvard Medical SchoolFacultyCurrentAcademic appointment
Massachusetts General HospitalAttending Physician, Emergency MedicineCurrentClinical practice
PepGen Inc. (NASDAQ: PEPG)DirectorSince Nov 2020Public company directorship
Aerovate Therapeutics, Inc. (NASDAQ: AVTE)DirectorSince Aug 2020 (also Oct 2018–Feb 2020)Public company directorship
Vor Biopharma Inc. (NASDAQ: VOR)DirectorSince Feb 2019Public company directorship

Board Governance

  • Board class/tenure: Class I director; board is staggered into Classes I–III; Class I (including Resnick) up in 2025 and re‑elected to 2028 .
  • Independence: Board determined all non‑employee directors are independent; CEO is not independent .
  • Committees: Current committee rosters do not include Dr. Resnick—Audit (Stelzer, Clancy, Fleming; Stelzer chair), Compensation (Viney chair; Booth, Iancovici, Stelzer), Nominating & Governance (Clancy chair; Ruddy, Thompson) .
  • Attendance: Each director attended at least 75% of board and applicable committee meetings during 2024 .
  • Leadership structure: Independent chair (Paul Clancy); CEO role separated from chair .
  • Shareholder support: 2025 election results—Resnick 42,090,273 For / 602,898 Withheld / 496,255 Broker non‑votes .

Fixed Compensation

  • 2024 director pay: Resnick received no cash or equity compensation due to affiliation with RA Capital; similarly Booth (Atlas), Iancovici (TPG), Fleming (Enavate), Thompson (OrbiMed) received none .
  • 2024 values (from Director Compensation Table): Resnick: Cash $0; Options $0; Total $0 .

Non‑Employee Director Compensation Policy (effective Feb 6, 2025):

  • Cash retainers (annual): Board member $40,000; Non‑executive chair +$30,000; Committee retainers—Audit: member $8,000 / chair $16,000; Compensation: member $6,000 / chair $12,000; Nominating & Governance: member $4,500 / chair $9,000 .
  • Equity: Initial option grant to purchase 39,919 shares (3‑yr annual vesting); Annual option grant to purchase 19,959 shares (vests by next annual meeting or 1‑year) .
  • Policy terms include 10‑year option life, FMV strike, full acceleration on “sale event,” and annual compensation caps [$1,000,000 first year/$750,000 thereafter] .

Performance Compensation

  • Director equity awards are time‑based (options) under the 2025 policy; no performance metrics apply to director compensation (metrics not disclosed/used for directors) .

Other Directorships & Interlocks

Company/EntityTypeRelation/RolePotential Interlock/Conflict Considerations
RA Capital Management, L.P.Investor (≥5% holder group)Resnick is Senior Managing DirectorRA Capital beneficially owns 23.7% of SION; insider affiliation creates potential related‑party and influence considerations
TPG Growth affiliatesInvestor (≥5% holder group)Fellow director Iancovici is Managing Director at TPGTPG affiliates own 15.2%
OrbiMedInvestor (≥5% holder group)Fellow director Thompson is member at OrbiMedOrbiMed holds 8.4%
Atlas VentureInvestor (≥5% holder group)Fellow director Booth is GP at AtlasAtlas holds 8.4%
Enavate/Sionna AggregatorInvestor (≥5% holder group)Fellow director Fleming is EVP at EnavateSionna Aggregator holds 5.6%

Compensation Committee interlocks: None—no SION officer served on another company’s comp committee, and comp committee members were not SION officers .

Equity Ownership

HolderShares Beneficially Owned% OutstandingNotes
Joshua Resnick, M.D., M.B.A.No shares reported as of Apr 15, 2025; “—” indicates zero; less than 1% threshold not met
RA Capital affiliated funds (group)10,445,32223.7%13D reporting entities; RA Capital is a significant shareholder
  • Pledging/hedging: Company insider trading policy expressly prohibits hedging and pledging by directors and officers .
  • Ownership guidelines: Not disclosed in proxy .

Related-Party and Financing Exposure

  • Series C financing (Mar 4, 2024): RA Capital affiliates purchased 5,456,093 shares ($53,262,380); multiple 5%+ holders affiliated with SION directors also participated (Atlas $11,265,026; OrbiMed $19,999,995; TPG Growth $17,235,211; Sionna Aggregator/Enavate $27,499,993; Viking $24,999,994) .
  • IPO participation (Feb 2025): RA Capital affiliates purchased 1,125,000 shares ($20,250,000); TPG affiliates 1,125,000 ($20,250,000); Atlas 60,000 ($1,080,000); OrbiMed 550,000 ($9,900,000); Sionna Aggregator 550,000 ($9,900,000) .
  • Related‑party policy: All related‑person transactions require board/audit committee approval and must be on no‑less‑favorable terms than third‑party deals .

Director Election Results (2025)

NomineeVotes ForVotes WithheldBroker Non‑Votes
Joshua Resnick, M.D., M.B.A.42,090,273602,898496,255
Bruce Booth, D.Phil.42,076,029617,142496,255
Lucian Iancovici, M.D.42,090,273602,898496,255

Expertise & Qualifications

  • Biopharma investor/operator and physician: RA Capital leadership, clinical practice at MGH; faculty at Harvard Medical School .
  • Education: B.A. (Williams—Chemistry), M.D. (UPenn Perelman), M.B.A. (Wharton) .
  • Board‑stated rationale: Investor experience and medical background as relevant skills for Sionna’s strategy .

Fixed Compensation (Detail)

Component (2024)Amount
Cash retainer$0 (due to RA Capital affiliation)
Equity awards$0 (no outstanding grants as of 12/31/24)
Total$0

2025 Policy Reference (applies to non‑employee directors generally):

  • Board member annual cash retainer $40,000; committee retainer schedule and chair premiums as above; initial option 39,919 shares; annual option 19,959 shares; time‑based vesting .

Performance Compensation (Director)

ElementStructureMetrics
Director equity compensationStock options per policy (initial/annual), time‑based vestingNo performance metrics disclosed for director pay

Governance Assessment

  • Strengths

    • Independence affirmed; not on management; board majority independent with independent chair; strong shareholder support in 2025 election .
    • Prohibitions on hedging/pledging reduce misalignment risk; formal related‑party transaction policy; independent audit and comp committees in place .
    • 2024: declined cash/equity fees due to RA Capital affiliation, reducing direct cash conflicts; clear disclosure of investor participation in financings .
  • Risks/Red Flags to Monitor

    • Significant investor affiliation: RA Capital is a 23.7% holder; Resnick is a Senior Managing Director—potential for perceived conflicts in financing, strategic transactions, or capital allocation; ensure continued recusal/committee oversight where appropriate .
    • Personal ownership alignment: No reported personal beneficial ownership in SION as of the record date; while fund ownership aligns investor interests, lack of individual holdings may limit personal “skin in the game” .
    • Concentrated investor board representation (Atlas/OrbiMed/TPG/Enavate) necessitates vigilant related‑party governance and independent committee functioning .
  • Overall View

    • Governance quality appears adequate with independent chair, established committees, and policies; however, investor‑affiliated representation (including Resnick) and substantial related‑party financings require ongoing transparency, recusals, and rigorous audit/compensation committee oversight to maintain investor confidence .