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Dave Lemus

Non-Executive Director at Silence Therapeutics
Board

About Dave Lemus

Independent non-executive director at Silence Therapeutics since June 2018; age 62 (as of the 2025 proxy). Career finance/operator with prior CFO/COO roles, CEO experience, and IPO execution; M.S. (MIT), B.S. (University of Maryland), and active CPA (Maryland). Board-designated “audit committee financial expert.” Reappointed by shareholders at the June 26, 2025 AGM.

Past Roles

OrganizationRoleTenure/NotesCommittees/Impact
miRecule Inc.Chief Operating Officer; Chief Financial Officer; DirectorPresentActive operator and director; external to SLN
Ironshore Pharmaceuticals Inc.Chief Executive OfficerPriorCEO experience
Medigene AGChief Operating Officer & Chief Financial OfficerPriorDual COO/CFO responsibilities
Sigma Tau Pharmaceuticals, Inc.Chief Executive OfficerPriorCEO experience
MorphoSys AGChief Financial Officer; EVP13 years; led Germany’s first biotech IPO (1999)Capital markets/IPO leadership

External Roles

OrganizationRoleStatusPublic/PrivatePotential Interlocks/Notes
miRecule Inc.COO, CFO, DirectorCurrentPrivateNo related-party transactions disclosed with SLN
BioHealth Innovation, Inc.DirectorCurrentNon-profit/PrivateGovernance network role
Sorrento Therapeutics Inc. (OTC: SRNEQ)Non-executive directorPriorPublic (OTC)Prior public company directorship

Board Governance

  • Independence: Determined independent by SLN’s Board under Nasdaq standards.
  • Committee assignments (2024–2025): Audit & Risk Committee Chair; member of Remuneration and Nominations Committees. Remuneration Committee chair role transitioned to Tim McInerney on May 5, 2025; Lemus remains a member.
  • Financial expert: Designated “audit committee financial expert” with requisite financial sophistication.
  • Board activity/attendance: Board met 11 times in 2024; each director attended ≥75% of board and committee meetings. Independent directors held 11 executive sessions.
  • Re-appointment vote (AGM 2025): 77,007,634 For; 28,445 Against; 1,221,309 Abstain. Strong shareholder support.

Fixed Compensation

ComponentAmountDetail
Annual director service retainer (cash)$38,000Applicable to non-executive directors
Audit & Risk Committee Chair fee$16,000In lieu of member fee
Remuneration Committee member fee$5,000Member fee
Nominations Committee member fee$0No fee disclosed for Nominations members
Total fees earned in 2024 (Lemus)$59,000Matches $38k + $16k + $5k

Notes:

  • No pension benefits or cash in lieu for non-executive directors.
  • Appointment letters allow termination on notice and set conduct/conflict standards.

Performance Compensation

Equity Element2024 Grant (Lemus)VestingValuation/TermsChange in Control Treatment
Stock options (non-exec)$157,065 grant-date fair valueGenerally monthly over 36 monthsExercise price = FMV on grant date; 10-year termFull vesting for non-exec directors who remain service providers until immediately prior to a Change in Control
Options outstanding (12/31/2024)144,000 optionsOutstanding as of year-end

Additional detail:

  • Non-executive annual grants historically in Q1; 2024 grant date April 1, 2024.
  • Equity under Non-Employee Sub-Plan to the 2023 Equity Incentive Plan.

Other Directorships & Interlocks

CompanyCurrent/FormerCommittee Roles ElsewherePotential Conflicts with SLN
miRecule Inc.CurrentNot disclosedNo SLN related-party transactions disclosed involving Lemus
BioHealth Innovation, Inc.CurrentNot disclosedNone disclosed
Sorrento Therapeutics Inc.FormerNon-exec directorNone disclosed

Expertise & Qualifications

  • Finance and capital markets expertise (CFO/EVP; IPO leadership), operator experience (COO/CEO).
  • Board-designated audit committee financial expert.
  • Education: M.S. (MIT), B.S. (University of Maryland); active CPA (Maryland).

Equity Ownership

Ownership DetailAmount
Total beneficial ownership (ordinary shares)108,861 (consists of 7,527 shares held and 101,334 options exercisable within 60 days of March 31, 2025)
Percent of shares outstandingLess than 1%
Options exercisable within 60 days (3/31/2025)101,334
Options outstanding (12/31/2024)144,000

Alignment policies:

  • No stock ownership guidelines for directors or employees; no policy expressly limiting hedging or pledging.
  • Company maintains a comprehensive clawback policy.

Governance Assessment

Strengths

  • Independent director with deep finance and biotech operating experience; designated audit committee financial expert; chairs Audit & Risk Committee.
  • Committee engagement across audit, remuneration, and nominations; strong re-appointment support at AGM 2025.
  • Robust Board/committee workload with ≥75% attendance across directors; 11 independent director executive sessions in 2024.
  • Shareholder endorsement of 2024 directors’ remuneration report; Say-on-Pay supported.

Risks / RED FLAGS to monitor

  • No director stock ownership guidelines and no explicit anti-hedging/pledging policy; potential misalignment/optics risk.
  • Low personal ownership (<1%); common for small-cap biotech NEDs but can be perceived as limited “skin-in-the-game.”
  • Multiple external responsibilities (operator + board roles) could pose time-allocation/perceived conflict risks; however, no related-party transactions are disclosed and Board affirms independence.

Supporting Votes/Policies (Context)

AGM 2025 ResolutionResult (For/Against/Abstain)
Re-appoint Dave (David) Lemus as director77,007,634 / 28,445 / 1,221,309
Say-on-Pay (NEO compensation)70,771,045 / 3,076,664 / 4,409,679
Directors’ U.K. remuneration report (advisory)70,798,897 / 1,838,213 / 5,620,278

Notes on Related-Party Exposure

  • Proxy describes related-person transactions ≥$120,000 since Jan 1, 2023; none disclosed involving Lemus.

Committee Composition Snapshot (2024/early-2025)

CommitteeRole (Lemus)Notes
Audit & RiskChairFinancial expert; oversees audit firm, controls, risk
RemunerationMemberChair role moved to Tim McInerney on May 5, 2025
NominationsMemberGovernance/succession focus

All citations: SLN DEF 14A (May 16, 2025) and SLN 8-Ks (May 6, 2025; June 27, 2025).