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Tim McInerney

Non-Executive Director at Silence Therapeutics
Board

About Tim McInerney

Tim McInerney (age 64) is an independent non‑executive director of Silence Therapeutics plc, appointed May 5, 2025. He chairs the Remuneration Committee and serves on the Audit & Risk Committee. A pharmacist by training (B.S., St. John’s University; post‑graduate residency at NYU Medical Center), he brings 30+ years across pharma operations and healthcare capital markets, including roles at Bristol‑Myers Squibb, Bear Stearns, Ladenburg Thalmann, Paramount BioCapital, Riverbank Capital, and Castle Hill Capital Partners .

Past Roles

OrganizationRoleTenureCommittees/Impact
Castle Hill Capital Partners, Inc.Managing DirectorMay 2017 – presentCapital advisory in healthcare .
Riverbank Capital, Inc.Managing DirectorJun 2007 – Apr 2017Healthcare investment/capital markets .
Paramount BioCapital, Inc.Managing Director; oversaw distribution of private equity products1992 – Mar 2007Raised capital for startups/private placements in healthcare .
Ladenburg Thalmann & Co.Research Analyst (biotech)Pre‑1992Equity research coverage in biotechnology .
Bear Stearns & Co.; Shearson Lehman Brothers, Inc.Equity SalesPre‑1992Institutional equity sales .
Bristol‑Myers SquibbSales & MarketingPre‑1992Commercial roles in pharma .

External Roles

OrganizationRoleTenureCommittees/Impact
Corino Therapeutics (private)Co‑founding investor and Board MemberNot disclosed (current)Early‑stage investor/director .
Emisphere Technologies (public; acquired by Novo Nordisk)DirectorJun 2012 – Dec 2020Chaired Special Committee negotiating $1.8B sale to Novo Nordisk (Dec 2020) .
Insite Vision (public; acquired by Sun Pharma)Chairman; Director2008 – 2015Board leadership through sale .
Edgemont Pharmaceuticals (acquired by Alvogen)Chairman; DirectorMay 2010 – May 2016Board leadership through sale .
ZIOPHARM OncologyDirector2005 – Jun 2015Board service in oncology biotech .

Board Governance

  • Independence: The Board determined McInerney is independent under Nasdaq rules; the majority of SLN’s Board is independent .
  • Committee assignments (effective May 5, 2025): Chair, Remuneration Committee; Member, Audit & Risk Committee .
  • Board leadership: Independent Chair (Iain Ross) separates Chair/CEO roles .
  • Board and executive sessions: The Board met 11 times in 2024; all directors who served during 2024 attended at least 75% of Board/committee meetings; independent directors held 11 executive sessions in 2024 (McInerney joined in 2025) .

Fixed Compensation

ComponentAmountNotes
Annual Board Retainer (Non‑Executive Director)$56,000As disclosed on appointment .
Remuneration Committee Chair fee$10,000Policy amount; additional to director retainer; not explicitly repeated in 8‑K .
Audit & Risk Committee Member fee$8,000Policy amount; additional to director retainer; not explicitly repeated in 8‑K .

Policy context: Standard non‑executive annual director service retainer is $38,000; Board chair retainer $117,000; committee fees as above; expenses reimbursed; no pension for non‑executive directors .

Performance Compensation

Award TypeShares/UnitsVestingExercise Price/TermChange‑of‑Control TreatmentSource
Initial Non‑Employee Option (2025 appointment)48,000 ordinary sharesMonthly over 36 monthsFMV exercise price; 10‑year term under 2023 EIPFor non‑exec directors: outstanding equity fully vests upon change in control if service continues until immediately prior to closing .
Annual Non‑Employee Option (recurring)48,000 ordinary shares per yearMonthly over 36 monthsFMV exercise price; 10‑year term under 2023 EIPSame as above .
  • Equity plan mechanics: Non‑employee awards typically are options (also permits RSUs/SARs), priced at 100% of FMV on grant date; no maximum award; approvals by full Board; vesting monthly over 36 months; accelerated vesting on change‑in‑control as noted .
  • Performance metrics: Director equity awards are time‑based, not performance‑conditioned .

Other Directorships & Interlocks

CompanyRelationship to SLNPotential Interlock/Conflict Flag
Emisphere (sold to Novo Nordisk), Insite Vision (sold to Sun Pharma), Edgemont (sold to Alvogen), ZIOPHARMFormer boards in broader biopharma; not direct siRNA competitorsNo related‑party transactions disclosed by SLN; McInerney reported no Item 404(a) transactions at appointment .
Corino Therapeutics (private)Current private boardNo SLN‑reported related‑party dealings .

Expertise & Qualifications

  • Technical and sector expertise: Pharmacy degree and residency (drug information systems); biotech sell‑side research; equity sales; private equity distribution; pharma commercial operations .
  • Capital markets/M&A: Led distribution of PE products; material roles in early financings (e.g., Kite, Cougar); chaired Emisphere special committee for $1.8B sale to Novo Nordisk .
  • Governance: Prior audit, compensation, and governance committee service across multiple boards; now chairs SLN’s Remuneration Committee and sits on Audit & Risk .

Equity Ownership

As of/SourceBeneficial Ordinary SharesDerivative Holdings DisclosedNotes
Form 3 (event 05/05/2025; filed 05/20/2025)0“No securities are beneficially owned”Initial statement of beneficial ownership at appointment .
  • Insider trading policy: SLN maintains a formal insider trading policy .
  • Stock ownership guidelines: SLN does not currently maintain stock ownership guidelines for employees or non‑employee directors, and has no policy expressly limiting hedging or pledging of company stock .
  • Indemnification/D&O: Standard deeds of indemnity and D&O insurance maintained; SLN intends to enter its standard deed with McInerney .

Governance Assessment

  • Positives

    • Independent director with deep healthcare financing and board experience; appointed to lead Remuneration Committee and oversee pay governance; member of Audit & Risk, reinforcing financial oversight .
    • No related‑party transactions disclosed; 8‑K states no material interest in Item 404(a) transactions .
    • Board structure features independent Chair and regular executive sessions among independent directors; strong 2024 attendance for existing directors .
    • Remuneration Committee uses independent advisor (AON) and oversees clawback policy design and equity plans; committee members are independent under Nasdaq standards .
  • Risks and red flags

    • RED FLAG: No stock ownership guidelines for directors and no explicit anti‑hedging/anti‑pledging policy—potential misalignment and risk management concern for investors .
    • Director equity awards are time‑based options without performance conditions; while standard for non‑execs, this reduces pay‑for‑performance linkage at the director level .
    • Cash retainer disclosure for McInerney ($56,000) differs from policy’s standard retainer ($38,000); clarity on whether committee fees are incremental would aid comparability (policy suggests they are) .
    • Workload/overboarding considerations: Significant external engagements historically; however, no specific attendance data for McInerney yet (he joined in 2025) and SLN reports strong 2024 attendance for then‑serving directors .
  • Signals to monitor

    • First U.S. domestic issuer say‑on‑pay vote occurred at 2025 AGM; track shareholder support and Remuneration Committee’s response (McInerney as chair) .
    • Form 4 filings for option grants and any subsequent insider transactions to assess ownership build and alignment (initial Form 3 showed zero holdings) .

Director Compensation (Context)

Name (2024)Cash Fees ($)Option Awards ($)Total ($)
Tim McInerney
Note: McInerney joined in 2025; 2024 director compensation table shows no 2024 amounts for him .

2025 appointment terms for McInerney: $56,000 annual retainer; initial and annual option grants of 48,000 ordinary shares each, vesting monthly over 36 months .

Compensation Structure Notes (Policy)

  • Committee fees (policy): Remuneration Chair $10,000; Audit & Risk Member $8,000; Director retainer $38,000; Board Chair $117,000 .
  • Non‑executive equity: Options/SARs at FMV; 10‑year term; monthly vesting over 36 months; full vesting upon change in control if in service until immediately prior to closing .

Related‑Party and Conflicts Check

  • Related‑party transactions: None disclosed involving McInerney; 8‑K confirms no Item 404(a) transactions at appointment .
  • Policy framework: SLN maintains a related person transaction policy overseen by the Audit & Risk Committee .

Insider Filings

FilingDate (event/filed)Summary
Form 305/05/2025 event; 05/20/2025 filedInitial beneficial ownership: no securities beneficially owned .

Power of Attorney authorizing Section 16 filings executed May 7, 2025 .