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Angelos M. Stergiou

Angelos M. Stergiou

President and Chief Executive Officer at SELLAS Life Sciences GroupSELLAS Life Sciences Group
CEO
Executive
Board

About Angelos M. Stergiou

  • President, CEO, and Director of SELLAS Life Sciences Group since December 2017; founder and former Chairman/Vice Chair of Private SELLAS prior to its 2017 business combination . Age 49 as of the 2025 proxy .
  • Education/credentials: M.D.; Sc.D. h.c.; undergraduate in pre‑medicine/biology/chemistry; fellow/member of several medical societies .
  • Performance context: pre‑commercial biotech with no recurring revenue; pay-versus-performance disclosure shows PEO Compensation Actually Paid of $667k (2022), $801k (2023), $1.333m (2024) versus cumulative TSR value of $42.68 (2022), $19.17 (2023), $18.81 (2024) and net losses of $41.3m, $37.3m, and $30.9m, respectively . The company notes it does not use net income/loss as a compensation metric given its stage; incentives focus on long-term clinical and corporate milestones .

Past Roles

OrganizationRoleYearsStrategic impact
SELLAS Life Sciences Group (post‑merger)President, CEO, DirectorDec 2017–presentLed public company; ongoing development of WT1 peptide vaccine platform licensed from MSK .
Private SELLAS (pre‑merger)Founder; Chairman (2012–Jul 2016); Vice Chairman (Jul 2016–Dec 2017); CEO/Director2012–2017Negotiated exclusive MSK license for WT1 vaccine; transferred some founder shares to MSK as consideration .
Genesis Life Sciences (now Genesis Research)President & COO2009–2011Built health economics/pricing-reimbursement/market access capabilities .
Biovest International / Accentia BiopharmaceuticalsVP/Head of Drug Development; CMO (subsidiary)2004–2008Led Phase 3 development of BiovaxID; ASCO plenary presentation (2009) .
PAION AG (with Forest Labs JSC)U.S. program lead (desmoteplase); member of joint steering/oversight committee2002–2004Advanced neurovascular asset through partnered governance .

External Roles

OrganizationRoleYearsNotes
Cleara Biotech B.V.DirectorSince Jan 2022Private biotech board service .
Kentucky Wesleyan CollegeBoard of TrusteesMar 2017–Jan 2021Prior academic/non‑profit governance .
Professional societiesFellow/member (RSM, WMA, AAPCR, ACRP)OngoingProfessional affiliations .

Fixed Compensation

Metric20232024
Base salary ($)625,000 650,000
Target bonus (% of salary)≥50% (per employment agreement) ≥50% (per employment agreement)
All other comp ($)4,243 (benefits) 4,760 (benefits)

Notes

  • CEO’s target cash bonus is set at no less than 50% of base salary by contract; actual goals are approved annually .

Performance Compensation

Short‑term incentive (cash)

Metric20232024
Non‑equity incentive plan payout ($)275,000 339,625
  • Framework and metrics: CEO’s bonus is 100% based on achievement of annual corporate goals focused on clinical development milestones, business development activities, and cash management/financing objectives; specific weightings/targets not disclosed .

Equity awards granted (structure and vesting)

Grant dateTypeShares/UnitsExercise priceVesting
Jan 2024Options238,500$0.519525% vested Jan 2025; remainder monthly over 36 months; expires 01/22/2034 .
Jan 2024RSUs159,000n/a25% each Dec 1 starting 2024 until fully vested (service‑based) .
Feb 2023Options217,500$3.3425% vested Feb 2024; remainder monthly over 36 months; expires 02/02/2033 .
Feb 2023RSUs58,000n/a25% each Dec 1 starting 2023 until fully vested (service‑based) .
Mar 2021RSUsn/a25% each Dec 1 starting 2021 (service‑based) .
Jan 2022RSUsn/a25% each Dec 1 starting 2022 (service‑based) .
Mar 2020RSUsn/a50% upon Phase 3 REGAL primary endpoint; 50% upon FDA BLA approval (performance‑based) .

Pay versus performance (company‑disclosed)

YearPEO SCT Total ($)PEO Compensation Actually Paid ($)Value of $100 TSRNet loss ($000s)
20221,952,245 667,297 42.68 (41,301)
20231,752,638 801,284 19.17 (37,340)
20241,189,773 1,333,403 18.81 (30,881)

Equity Ownership & Alignment

Beneficial ownership (as of April 17, 2025)

HolderShares beneficially owned% of outstandingShares outstanding reference
Angelos M. Stergiou651,657 <1% 94,548,425 shares outstanding

Outstanding unvested RSUs at 12/31/24 (market value using $1.04/share)

GrantUnvested unitsMarket value ($)
Mar 2020 RSUs95,000 98,800
Jan 2022 RSUs11,000 11,440
Feb 2023 RSUs29,000 30,160
Jan 2024 RSUs119,250 124,020

Selected option holdings (12/31/24)

GrantExercisableUnexercisableExercise priceExpiration
03/13/20181,900 $262.00 03/13/2028
03/18/20198,500 $69.00 03/18/2029
03/12/202070,000 $1.89 03/12/2030
03/04/2021111,094 7,406 $8.00 03/04/2031
01/31/2022120,313 44,688 $5.34 01/31/2032
02/02/202399,688 117,813 $3.34 02/02/2033
01/22/2024238,500 $0.5195 01/22/2034

Alignment/Policies

  • Insider Trading Policy prohibits short sales, hedging, options transactions, and pledging/margining of company stock (exceptions may be granted with demonstrated financial capacity) .
  • The proxy provides a summary of stock ownership guidelines following shareholder feedback; details not specified in the excerpts .

Vesting cadence and potential selling pressure

  • RSUs vest 25% on each Dec 1 annually for service‑based grants; 2024 RSUs began vesting Dec 1, 2024, with additional tranches on Dec 1 of subsequent years .
  • Options from 2023 and 2024 grants vest one‑quarter on the first anniversary of grant, then in 36 equal monthly installments thereafter, creating steady monthly vesting through early 2028 for the 2024 grant .

Employment Terms

  • Agreement: 2019 Stergiou Agreement effective July 1, 2019; continues until terminated per terms; initial base $525,000 (subject to review), target bonus no less than 50% of base; eligible for equity; excise tax “cutback” to avoid 280G penalties .
  • Termination (without cause/for good reason): 18 months of base salary paid over 12 months plus pro‑rated annual STI for the year of termination, and COBRA premium reimbursement if elected .
  • Change in control (double trigger: one month prior to or within one year following a CIC): 24 months of base salary over 12 months, 1.5x target bonus, COBRA reimbursement, and full accelerated vesting of all equity awards .
  • Termination with cause or resignation without good reason: accrued benefits only; other rights terminate except legally required benefits .

Board Governance (director service, committees, independence)

  • Board/role: Class III director; nominated for re‑election at 2025 meeting for a term through 2028 .
  • Independence/leadership: Not independent (employee director). Board has an independent Chair (John Varian) since June 2024; company emphasizes separation of Chair/CEO for governance effectiveness .
  • Committees: Member of the Board’s Science Committee; the committee met four times in 2024 .
  • Attendance: All directors attended 100% of 2024 Board and committee meetings .
  • Director pay: As CEO/director, he receives no additional compensation for Board service .

Compensation Committee & Peer Benchmarking

  • Independence and process: Independent Compensation Committee (chair: Katherine Bach Kalin) met four times in 2024; CEO excluded from deliberations on his compensation .
  • Consultant: Radford (Aon) engaged; no conflicts identified .
  • 2024 peer group criteria: pre‑commercial oncology biopharmas, Phase 2/3 stage, market cap ≤$250m, <50 employees; named peers include Actinium, Cardiff Oncology, Checkpoint Therapeutics, Corvus, Cue Biopharma, Cyclacel, Elevation Oncology, Equillium, Galera, GlycoMimetics, Immunic, Leap Therapeutics, MEI Pharma, PDS Biotech, Selecta Biosciences, Verastem, Vincerx, ContraFect (and others per list) .

Say‑on‑Pay & Shareholder Feedback

  • 2024 say‑on‑pay: Approved by a majority of votes cast; company expanded engagement afterward .
  • Engagement outcomes: Discussions with major holders and proxy advisors; investors and Glass Lewis indicated the program is typical for size/sector; request for more detail on stock ownership guidelines addressed in proxy .
  • 2025: Board recommends “FOR” say‑on‑pay and “ONE YEAR” frequency for say‑on‑frequency .

Investment Implications

  • Alignment and incentives: CEO pay design skews to equity (options and RSUs) with cash STI tied 100% to corporate goals (clinical/BD/capital), appropriate for a pre‑commercial biotech; presence of Dodd‑Frank‑compliant clawback and anti‑hedging/pledging policy supports alignment .
  • Retention/CIC economics: Robust severance (18 months base plus pro‑rated bonus) and CIC double‑trigger benefits (24 months base, 1.5x target bonus, full equity acceleration) reduce retention risk but can create deal‑related dilution/overhang; full equity acceleration on CIC is a notable shareholder consideration .
  • Vesting and potential selling pressure: Predictable monthly option vesting (2023–2028) and annual RSU tranches each Dec 1 may create periodic liquidity windows; 2024 option strike ($0.5195) and service‑based RSUs increase near‑term realizability if performance/capital improves .
  • Track record/TSR context: Compensation Actually Paid rose in 2024 while cumulative TSR remained depressed ($18.81 from a $100 base), reflecting long‑cycle clinical value creation vs. near‑term market returns; investors should monitor milestone‑linked RSUs (Phase 3/BLA triggers) for value realization alignment .