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Samir Gharib

President and Chief Financial Officer at SPRUCE BIOSCIENCES
Executive

About Samir Gharib

Samir Gharib is President (since January 2022) and Chief Financial Officer (since May 2020) of Spruce Biosciences, Inc.; age 42 as of the 2025 proxy. He holds a B.S. and MBA from UC Berkeley’s Haas School of Business and is a licensed CPA in California . Company context during his tenure includes a going‑concern warning (cash and equivalents $38.8M as of 12/31/2024) and an April 2025 delisting from Nasdaq to OTC, with a proposed reverse split to regain listing, highlighting financing urgency tied to executive PSUs .

Past Roles

OrganizationRoleYearsStrategic Impact
Spruce BiosciencesPresidentJan 2022–presentCo-led financing and strategic objectives; compensation tied to financing/strategic PSUs .
Spruce BiosciencesChief Financial OfficerMay 2020–presentBuilt finance function pre/post IPO; options and RSUs/PSUs structure emphasizes retention and capital access .
Stemedica Cell TechnologiesChief Financial OfficerOct 2018–Sep 2019CFO for cell therapeutics firm (underserved medical conditions), bringing biotech finance experience .
Benchmark Financial PartnersManaging Director; financial consultantSep 2017–Oct 2018; Sep 2019–May 2020Strategic advisory; later consulted across companies prior to joining Spruce .
Revance TherapeuticsVP Finance & AdministrationOct 2013–Sep 2017Scaled finance/admin at commercial-stage biotech .
Talon TherapeuticsCorporate Controller / Director of FinanceJan 2011–Sep 2013Led controllership/finance in public biotech .

External Roles

OrganizationRoleYearsStrategic Impact
Berkeley SkyDeckAdvisorJan 2020–presentStartup mentorship and network reach relevant to capital raising .

Fixed Compensation

YearBase Salary ($)Target Bonus (%)Actual Bonus Paid ($)Notes
2024465,100 45% of base 209,925 (retention bonus; paid in 2024) Board guaranteed retention payments for 2024 bonuses .
2023447,200 45% of base (confirmed for 2023) 30,186 (discretionary adjustment; paid early 2024) Separate non‑equity incentive payout of $201,240 for 2023 performance .

Performance Compensation

Equity Grants (RSUs and PSUs)

YearAward TypeGrant DateShares GrantedGrant Fair Value (per share / total $)Vesting and Performance Conditions
2024RSUMar 14, 2024154,000 Not separately stated for RSUs; PSU grant fair value used below25% vests 12/10/2025; remaining vests annually on anniversaries, subject to continued service .
2024PSUMar 14, 2024154,000 $0.8106 per share; total $249,665 Vests upon specified financing/strategic objectives; single‑installment vest if change‑of‑control or equity financing ≥$50M gross proceeds .
2023RSUDec 14, 2023154,000 Included in 2023 stock awards total $517,440 25% vested 12/15/2024; remaining vests annually, subject to continued service .
2023PSUDec 14, 2023154,000 $1.68 per share; performance‑probability basis (part of $517,440 total) Vests upon achievement of specified clinical development milestones anticipated in 2024 .

Option Awards Snapshot (as of 12/31/2024)

Grant DateExercisable (#)Unexercisable (#)Exercise Price ($)ExpirationNotes
06/08/2020118,483 1.64 06/07/2030 Early exercise feature .
08/07/202071,548 3.07 08/06/2030 Early exercise feature .
01/28/202153,854 1,146 20.08 01/27/2031 Standard monthly vest .
12/16/2021108,750 36,250 2.48 12/15/2031 Monthly vest .
01/03/202251,041 18,959 4.59 01/03/2032 Monthly vest .

Performance Metrics and Payout Mechanics

  • 2024 PSUs: financing/strategic objectives; accelerates on change‑of‑control or ≥$50M equity financing; creates direct linkage of payout to capital events .
  • 2023 PSUs: clinical milestone‑based; aligns payouts with pipeline execution .

Equity Ownership & Alignment

Date (Record)Direct Shares OwnedOptions/Derivatives Exercisable ≤60 daysTotal Beneficial OwnershipOwnership %Source
Apr 1, 2025350,550 427,218 (options) 777,768 1.8% 2025 DEF 14A.
Mar 25, 2024202,776 363,155 (options) 565,931 1.4% 2024 DEF 14A.
  • Hedging/pledging: Company insider trading policy prohibits hedging, short sales, margin accounts, and pledging of company securities, reducing misalignment risk from collateralization .
  • Vested vs unvested breakdown: As of 12/31/2024, multiple option grants remain partly unexercisable (see table). RSU/PSU tranches scheduled to vest beginning 12/10/2025 (2024 grants) and continued annual vesting thereafter (time‑based), which may create periodic supply overhang if net withheld shares are sold to cover taxes .

Employment Terms

  • Severance & change‑of‑control (Severance Plan): For a “regular termination,” 9 months salary continuation and up to 9 months COBRA benefits; for a “change‑in‑control termination,” 12 months salary, lump‑sum target bonus, up to 12 months COBRA, and full acceleration of all outstanding equity awards (performance awards at 100% of target) .
  • At‑will employment under offer letter; target bonus increased to 45% with appointment as President (Jan 2022); 2024 base salary set at $465,100 .
  • Clawback: Sarbanes‑Oxley §304 reimbursement for CEO/CFO in misconduct‑related restatements and Dodd‑Frank compliant recoupment policy adopted .
  • Policy restrictions: Prohibition on speculative trading, derivatives, and pledging as above .
  • Section 16 compliance note: Administrative delays caused untimely filing of three Form 4s for Mr. Gharib related to RSU vesting/net settlement, indicating process risk (not economic misreporting) .

Investment Implications

  • Pay‑for‑performance alignment: 2024 PSUs explicitly tied to financing and strategic outcomes, with accelerated vesting upon change‑of‑control or major equity financing (≥$50M). This structure strongly incentivizes capital raises and strategic transactions but can bias toward dilution, especially given going‑concern status and recent OTC transition .
  • Near‑term selling pressure: RSU tranches begin vesting on 12/10/2025; tax withholding may reduce float impact, but periodic vesting could create predictable supply overhang; options already largely exercisable add latent supply depending on price levels vs strikes ($1.64–$20.08) .
  • Retention risk: Guaranteed 2024 retention bonuses and robust severance/CIC protections support retention; however, company financing stress (going‑concern; delisting) elevates execution risk and potential strategic transaction likelihood that could trigger PSU acceleration .
  • Governance and risk controls: Anti‑hedging/pledging policy and clawbacks are shareholder‑friendly; Section 16 timeliness lapse is a minor procedural flag but not a compensation misalignment signal .

Key monitoring signals: (1) progress toward ≥$50M equity financing or change‑of‑control events (PSU triggers), (2) RSU vesting dates (12/10/2025 onward) and associated Form 4 activity, (3) any revisions to Severance Plan or compensation mix (e.g., shift from PSUs to RSUs), and (4) company listing status and capital runway disclosed in filings .