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Tracey Sacco

Chief Commercial Officer at Scholar Rock Holding
Executive

About Tracey Sacco

Chief Commercial Officer at Scholar Rock since February 2023; age 48 as of March 31, 2025; MBA (NYU Stern) and BA (Boston College). Biography highlights commercial leadership at Acceleron (SVP Global Strategic Marketing) and earlier commercial strategy roles at Sanofi/Genzyme, Oscient, and Pfizer . Company TSR improved from 36.43 to 173.99 on a $100 base from 2022–2024, while net income remained negative (2024: -$246M; 2023: -$166M; 2022: -$135M) . Scholar Rock notes it had no product revenue in 2023–2024; 2022 revenue was collaboration-based .

Past Roles

OrganizationRoleYearsStrategic Impact
The Nemetz GroupConsultantSep 2021–Jan 2023Commercial consulting ahead of apitegromab launch preparation
Acceleron Pharma (acquired by Merck)SVP, Global Strategic Marketing (roles of increasing responsibility)Jun 2012–Aug 2021Led global strategic marketing; commercial strategy for late-stage assets
Sanofi (formerly Genzyme)Commercial strategy/business development2005–2012Commercial and BD roles supporting therapy launches
Oscient PharmaceuticalsCommercial strategy/business development2005–2012Commercial and BD roles
PfizerCommercial strategy/business development2005–2012Commercial and BD roles

External Roles

No public company board roles disclosed .

Fixed Compensation

Metric2023
Annual Base Salary (policy)$415,000
Salary Paid (prorated from Feb 6 start)$367,115
Target Bonus % of Base40%
Actual Non-Equity Incentive Plan Bonus$143,192
Signing Bonus$25,000

Employment agreement: at-will; base salary reviewed annually; target annual incentive 40% of base .

Performance Compensation

Annual Cash Incentive Structure (2023)

ElementWeightingTargetActual/PayoutNotes
Corporate performance goals85% of bonusSet by BoardPaid via Non-Equity Incentive Plan ($143,192)Committee determines based on corporate goals
Individual performance15% of bonusCommittee discretionIncluded in payoutApplies to non-CEO NEOs

Equity Awards and Vesting

Grant TypeGrant DateQuantityStrike/ValueVestingExpiration
Stock optionsFeb 13, 2023225,000$10.00Equal quarterly over 16 quarters; first vest Apr 1, 2023Feb 13, 2033
RSUsNot disclosed for 2023

Outstanding equity table at 12/31/2023 shows Sacco with 225,000 options unexercisable; no RSUs reported for 2023 . Footnote confirms the 16-quarter vest schedule with initial vest on Apr 1, 2023 .

Trading Plans (Potential Selling Pressure/10b5-1)

Action DateTypeDuration/End DateAggregate SecuritiesDescription
Mar 19, 2024Adoption (Rule 10b5-1 plan)Jun 18, 202530,000Sale of common stock pursuant to plan
Dec 20, 2024Adoption (Rule 10b5-1 plan)Mar 25, 202643,000Exercises/sales; includes RSU sell-to-cover requirement
May 12, 2025Termination (Rule 10b5-1 plan)May 12, 202543,000Terminated plan; RSU sell-to-cover noted (Former CCO)

Equity Ownership & Alignment

  • Beneficial ownership: Not disclosed among named executive officers and directors in 2025 table (Sacco not listed) .
  • Hedging/pledging: Prohibited for officers (no short sales, derivatives, hedging, or pledging) per insider trading policy .
  • Clawback: Compensation Recovery Policy adopted Nov 28, 2023; clawback of incentive-based pay upon accounting restatement regardless of fault .

Employment Terms

TermProvision
Start date and roleEmployment agreement effective Feb 6, 2023; Chief Commercial Officer
Severance (no change-in-control)9 months base salary + reimbursement of COBRA premiums (up to 9 months) + 1x annual target bonus; subject to release
Severance (change-in-control within 18 months)12 months base salary + reimbursement of COBRA premiums (up to 12 months) + 1x annual target bonus; double-trigger acceleration of all time-based equity
Equity vesting accelerationImmediate vesting of all time-based awards upon qualifying termination within 18 months post change-in-control
Work locationCompany offices in MA; may work from home per policy
At-willEmployment may be terminated by either party at any time

Performance & Track Record

Metric202220232024
TSR – $100 initial value$36.43 $75.68 $173.99
Net Income (USD Millions)-$135 -$166 -$246
  • Launch preparedness: Sacco emphasized payer access advantages for SMA and analog learnings from SPINRAZA/risdiplam in a May 22, 2024 transcript, outlining engagement and uptake guidance as launch nears .
  • Company states no product revenue in 2023–2024 and limited collaboration revenue in 2022, shaping pay-versus-performance context .

Compensation Structure Analysis

  • Cash vs equity mix (2023): Significant equity emphasis via option grant ($1,732,703 grant-date fair value) vs cash salary ($367,115) and bonus ($143,192), plus a $25,000 sign-on bonus .
  • Incentive design: 85% corporate/15% individual bonus weighting for non-CEO NEOs aligns payouts to corporate milestones rather than personal discretion .
  • Change-in-control: Double-trigger acceleration and 12-month severance/bonus multiple may elevate retention but could increase payout leverage on M&A outcomes .

Risk Indicators & Red Flags

  • Hedging/pledging: Prohibited (alignment positive) .
  • Clawback: Implemented (alignment positive) .
  • 10b5-1 plans: Adoption and later termination may signal structured selling tied to vesting or tax obligations; RSU sell-to-cover noted by company policy .

Compensation Peer Group (Benchmarking)

2023 peer group includes Alector, Deciphera, Denali, Arrowhead, Rocket, Rhythm, SpringWorks, Dyne, Axsome, Biohaven, Pliant, and others used for pay benchmarking and annual salary review . Pay Governance served as compensation consultant; independence assessed .

Say-on-Pay & Shareholder Feedback

  • 2024: Company introduced advisory say-on-pay and say-on-frequency in proxy .
  • 2025: Advisory vote proposed; Committee/Board will consider outcomes in future compensation decisions .

Investment Implications

  • Strong alignment via significant equity/options and clawback/anti-hedging policies; bonus weighting ties to corporate goals, a positive for pay-for-performance .
  • Retention risk mitigated by 9–12 month severance and double-trigger acceleration; however, change-in-control economics could create meaningful payout leverage in M&A scenarios .
  • Trading plans around RSU vesting and option exercises suggest periodic selling pressure but are structured under Rule 10b5-1 and include sell-to-cover requirements for taxes (monitor future adoptions/terminations for timing signals) .
  • Execution focus: Commercial readiness commentary indicates proactive payer engagement for SMA; TSR improvements alongside persistent losses reflect market anticipation of commercialization rather than current profitability .