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Casi DeYoung

Chief Business Officer at Shattuck Labs
Executive

About Casi DeYoung

Casi DeYoung is Chief Business Officer at Shattuck Labs (STTK), serving since December 2019; she is 54 years old as of May 21, 2025, with a B.S. in Chemistry (Southwestern University) and an MBA from the McCombs School of Business at The University of Texas at Austin . Her career spans business development and corporate strategy roles across immuno-oncology and biotech; company performance context (for pay-performance alignment) shows revenues increased from 2022–2024 while EBITDA losses narrowed over the same period (table below) *.

Company performance (financial context):

MetricFY 2022FY 2023FY 2024
Revenues ($USD)$652,000 $1,657,000 $5,721,000
EBITDA ($USD)-$98,156,000*-$87,612,000*-$76,516,000*

Values retrieved from S&P Global.*

Past Roles

OrganizationRoleYearsStrategic Impact
ImmuneSensor TherapeuticsVice President & Chief Operating Officer2018–2019 Led corporate strategy, start-up operations, IP, first IND filing and initiation of first-in-human Phase I trial
Mirna Therapeutics, Inc.Chief Business Officer2014–2017 Drove business development in oncology-focused biopharma
Reata Pharmaceuticals, Inc.Vice President of Business Development2008–2013 Led BD at clinical-stage biopharma
ODC Therapy, Inc.Vice President of Business Development2005–2008 Advanced BD in cancer immunotherapy
EMD Pharmaceuticals / Merck KGaAVarious roles2000–2005 Commercial and operational roles at large-cap pharma

External Roles

OrganizationRoleYearsStrategic Impact
None disclosedNo public company board or external governance roles disclosed for DeYoung .

Fixed Compensation

  • Not disclosed for DeYoung in STTK’s EGC proxy NEO tables; the 2024–2025 proxy disclosures cover CEO, CFO, and CMO only, and do not present DeYoung’s base salary or bonus outcomes .
  • Employment agreement exists (Dec 9, 2019) with an amendment (Mar 12, 2021), indicating formal terms are in place but not summarized in proxy; full content is incorporated by reference in the 2024 10-K exhibits .

Performance Compensation

  • Company bonus framework for 2024: Compensation Committee set corporate performance goals (clinical milestones for SL‑172154, preclinical activities, manufacturing process improvements, and BD objectives); NEOs’ payouts were based on 60% corporate achievement plus individual performance evaluation .
  • DeYoung’s individual metrics, weightings, targets, and payouts are not disclosed; only the corporate program design is described at company level .

Equity Ownership & Alignment

  • Beneficial ownership: DeYoung is not itemized in the beneficial ownership tables; individual count is not disclosed in proxy (tables list NEOs/directors and group totals) .
  • Section 16 compliance: One Form 4 for DeYoung (covering three transactions related to RSU/option grants) was filed late due to administrative error, indicating active equity grant participation and reporting oversight risk .
  • Hedging/derivatives policy: Company prohibits short-term trading, short sales, publicly-traded options, and hedging transactions for insiders, strengthening alignment; pledging is not expressly addressed in disclosed policy text .

Employment Terms

  • Agreement: Employment Agreement dated Dec 9, 2019 and Amendment dated Mar 12, 2021 are on file (incorporated by reference), confirming contractual governance of duties/compensation; specific severance/change-of-control terms for DeYoung are not summarized in proxy .
  • Clawback: Company adopted a Rule 10D-1 clawback to recover excess incentive-based compensation over the prior three fiscal years upon a restatement .
  • Insider trading controls: Formal insider trading policy in place with prohibitions on hedging/derivatives and timing practices for grants (no “spring loading” or grant timing tied to MNPI) .

Investment Implications

  • Pay-for-performance transparency gap: As an EGC, STTK does not disclose DeYoung’s pay or award details; investors should request her salary, target bonus, equity mix, and ownership levels to assess alignment and retention risk .
  • Insider activity signal: DeYoung’s late Form 4 (administrative error) signals reporting process risk; monitor future Forms 4 for selling pressure and vesting events, especially given RSU/option participation .
  • Alignment policies are sound at company level (clawback, hedging prohibitions), but individual ownership/pledging status is unknown; obtain confirmations to rule out collateralization or guideline shortfalls .
  • Company fundamentals improved (revenues up; EBITDA losses narrowing), supporting potential alignment narratives; however, without individual targets/weights, linkage of DeYoung’s variable pay to program execution (e.g., BD milestones, trial starts) cannot be verified *.

Values retrieved from S&P Global.*