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Clay Siegall

Director at Shattuck Labs
Board

About Clay Siegall

Clay Siegall, Ph.D. (age 64) is an independent Class III director of Shattuck Labs (STTK), serving on the Board since March 2024. He is a veteran biotech operator and director with prior CEO, Chairman, and President experience, and holds a B.S. in Zoology (University of Maryland) and a Ph.D. in Genetics (George Washington University) . He is currently President, Chief Executive Officer, and Chairman of Immunome, Inc. (Nasdaq: IMNM) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Seagen Inc. (formerly Seattle Genetics)Chief Executive OfficerNov 2002 – May 2022Led growth and value creation; later acquired by Pfizer
Seagen Inc.PresidentJun 2000 – May 2022Senior executive leadership
Seagen Inc.Chairman, BoardMar 2004 – May 2022Board leadership
MorphImmune, Inc.President & CEOJan 2023 – Oct 2023Company later merged into Immunome

External Roles

CompanyRoleTenure/StatusNotes
Immunome, Inc. (Nasdaq: IMNM)President, CEO & ChairmanOct 2023 – PresentCurrent operating role
Tourmaline Bio, Inc. (Nasdaq: TRML)DirectorCurrentPublic company directorship
Nurix Therapeutics, Inc. (Nasdaq: NRIX)DirectorJun 2021 – May 2022Prior public company board
Ultragenyx Pharmaceutical Inc. (Nasdaq: RARE)DirectorFeb 2014 – Jun 2021Prior public company board
Alder BioPharmaceuticals, Inc.Director2006 – Oct 2019Prior public company board

Board Governance

  • Board class and independence: Class III director; Board has determined Dr. Siegall is independent under Nasdaq rules (all directors except the CEO are independent) .
  • Committee assignments: Member, Compensation Committee (no chair role) .
  • Committee activity: 2024 meetings – Audit (6), Compensation (4), Nominating & Corporate Governance (5) .
  • Attendance: Board met 8 times in 2024; each then-serving director attended at least 75% of aggregate Board and applicable committee meetings; six directors attended the 2024 annual meeting .
  • Board leadership: Independent Chairman (Dr. George Golumbeski); independent directors meet in executive session at every regular Board meeting .
  • Time commitment policy: Directors are expected to limit other boards to avoid interference with STTK duties; the Nominating & Corporate Governance Committee monitors adherence .
  • Compensation committee advisor: Aon engaged in 2024; committee determined advisor independence and no conflicts under Nasdaq/SEC rules .
  • Compensation committee interlocks: None during the prior three years (general disclosure) .

Fixed Compensation

YearFees Earned or Paid in Cash ($)
202435,627

Note: Dr. Siegall joined the Board in March 2024; fees reflect partial-year service .

Performance Compensation

Grant TypeGrant DateShares GrantedExercise PriceGrant Date Fair Value ($)Notes
Initial Stock Option (on joining Board)Mar 6, 202433,409$9.47250,000Initial non-employee director grant (Drs. Sasser and Siegall)
Annual Non-Employee Director OptionJun 21, 202427,700$4.3794,734Annual director equity award (options)
Option Awards (aggregate, 2024 compensation table)2024344,734Accounting grant-date fair value (ASC 718)

Other Directorships & Interlocks

CompanyRoleExchange/TickerCommittee Roles (if disclosed)
Immunome, Inc.President, CEO & ChairmanNasdaq: IMNMNot disclosed
Tourmaline Bio, Inc.DirectorNasdaq: TRMLNot disclosed
Nurix Therapeutics, Inc.Director (prior)Nasdaq: NRIXNot disclosed
Ultragenyx Pharmaceutical Inc.Director (prior)Nasdaq: RARENot disclosed
Alder BioPharmaceuticals, Inc.Director (prior)Not disclosed

No specific related-party transactions involving Dr. Siegall are disclosed in the proxy; the Board’s independence review discussed an ordinary-course vendor relationship tied to another director (Tempus AI), not Dr. Siegall .

Expertise & Qualifications

  • Extensive experience leading biotechnology companies (CEO/Chairman roles) and significant public company board service .
  • Education: B.S. in Zoology (University of Maryland); Ph.D. in Genetics (George Washington University) .
  • Board qualification narrative notes leadership and biotech domain expertise as reasons for nomination .

Equity Ownership

MetricDetail
Shares Beneficially Owned (as of Apr 1, 2025)11,137; less than 1% of outstanding
Shares Outstanding reference point47,899,240 (basis for percentage table)
Stock Options Held (as of Dec 31, 2024)61,109 options

Beneficial ownership includes shares with voting/investment power and those acquirable within 60 days under SEC rules .
STTK prohibits directors from short sales, trading in puts/calls, and hedging transactions in company securities (anti-hedging policy) .

Governance Assessment

  • Board effectiveness and alignment: Seat on Compensation Committee plus significant biotech leadership background supports strategic human capital oversight; independence affirmed by the Board .
  • Engagement/attendance: Board held 8 meetings in 2024; all directors met the 75% attendance threshold; independent chair and regular executive sessions bolster oversight quality .
  • Pay-for-performance alignment: 2024 director pay heavily equity-oriented (option awards $344,734 vs. cash $35,627), plus initial and annual option grants, signaling alignment with long-term shareholder value; ASC 718 accounting values disclosed .
  • Conflicts/related-party exposure: No related-person transactions disclosed for Dr. Siegall; the related-person policy requires Audit Committee review and approval of any such transactions; committee independence maintained .
  • Time-commitment/overboarding considerations: Dr. Siegall is an active CEO/Chairman at Immunome and sits on another public board (Tourmaline). STTK’s governance guidelines require directors to limit other boards; the Nominating & Corporate Governance Committee monitors compliance .
  • Compensation governance: Compensation Committee retained an independent consultant (Aon) with no conflicts in 2024; no compensation committee interlocks disclosed, supporting governance quality around pay decisions .

RED FLAGS (none disclosed):

  • No disclosed related-party transactions, option repricings, hedging/pledging exceptions, or low attendance issues for Dr. Siegall in the proxy .