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Taylor Schreiber

Taylor Schreiber

Chief Executive Officer at Shattuck Labs
CEO
Executive
Board

About Taylor Schreiber

Dr. Taylor Schreiber, 45, is co‑founder of Shattuck Labs and has served as CEO since January 29, 2020; he joined the board in 2017. He holds a B.A. in Biology (Bucknell) and an M.D./Ph.D. in Cancer Biology (University of Miami Miller School of Medicine) . Under his leadership, Shattuck terminated the legacy SL‑172154 program and pivoted to SL‑325 (DR3 antagonist) with an IND planned for Q3 2025 and a cash runway into 2027 . Recent financials: collaboration revenue was $5.7M in 2024 vs $1.7M in 2023, net loss was $75.4M in 2024 vs $87.3M in 2023; cash and equivalents were ~$73.0M at year‑end 2024 .

Selected FinancialsFY 2023FY 2024
Collaboration Revenue ($USD Millions)$1.657 $5.721
Net Loss ($USD Millions)$87.298 $75.410
Cash & Cash Equivalents + Investments ($USD Millions)$130.6 $73.0

Board governance: Schreiber serves as CEO and director; he is not independent. The independent Chairman role is separated (Dr. George Golumbeski), and independent directors hold executive sessions, mitigating dual‑role concerns .

Past Roles

OrganizationRoleYearsStrategic Impact
Shattuck LabsChief Scientific OfficerJan 2017 – Jan 2020Built pipeline; transitioned to CEO
Shattuck LabsChief Executive OfficerJan 2020 – PresentLed strategy; pivot to SL‑325
Shattuck LabsDirector (Board)2017 – PresentFounder‑level governance continuity

External Roles

OrganizationRoleYearsStrategic Impact
Heat Biologics (now NightHawk)VP R&D; later Chief Scientific OfficerMar 2014 – Dec 2016Immuno‑oncology leadership
Pelican TherapeuticsChairman, Scientific Advisory BoardJan 2011 – Mar 2017Oversight of immunotherapy strategy

Fixed Compensation

Metric202320242025 (current terms)
Base Salary ($)$525,000 $560,000 $565,600
Target Bonus %50% (per contract) 50% (target $280,000) 50%
Actual Bonus Paid ($)$262,500 $168,000
All Other Compensation ($)$5,385 $14,560

Year‑over‑year mix shifted heavily toward equity in 2024 (option awards $2.47M vs $0.24M in 2023) .

Performance Compensation

Annual Cash Incentive (2024)

MetricWeightingTargetActualPayoutVesting
Corporate goals (clinical SL‑172154; preclinical programs; manufacturing improvements; corp/dev objectives) Not disclosed$280,000 Assessed at 60% goal achievement $168,000 (60% of target) Cash (paid Feb 2025)

Equity Awards and Vesting

Award TypeGrant DateShares/UnitsExercise PriceVesting Triggers/ScheduleExpiration
Stock Option (time‑based)08/06/2020176,597 (exercisable) $4.67 25% at 1‑yr; monthly/quarterly thereafter 08/06/2030
Stock Option (time‑based)12/22/202027,563 (exercisable) $53.02 Same as above 12/22/2030
Stock Option (performance)01/10/2022178,150 (unearned) $7.43 Vests only if stock ≥ $18.00 for 30 consecutive trading days 01/10/2032
Stock Option (performance)01/25/2023162,000 (exercisable) $3.57 3 equal tranches at $4/$5/$6 for 30 consecutive days; achieved Jan 2024 01/25/2033
Stock Option (time‑based)01/12/2024330,100 (unexercisable) $9.41 25% at 1‑yr; remainder over 36 months 01/12/2034

Clawback: Nasdaq 10D‑1 policy to recover excess incentive‑based compensation after restatements (prior 3 fiscal years) .
Insider trading: Prohibits short sales, derivatives, hedging; pre‑clearance required for directors; caution against margin/pledging due to potential unlawful insider trading risk .

Equity Ownership & Alignment

Ownership DetailAmount
Total Beneficial Ownership (shares)3,045,758
Ownership (% of outstanding)6.4%
Components2,610,750 via Houghton Capital Holdings LLC (controlled by Schreiber) ; 71,002 direct ; 364,006 options exercisable within 60 days
Excluded Performance Options178,150 (subject to $18 stock‑price trigger)
Vested vs Unvested OptionsVested: 176,597 (2020), 27,563 (2020), 162,000 (2023) ; Unvested/Unearned: 330,100 (2024 time‑based), 178,150 (2022 performance)
Hedging/PledgingCompany policy bans hedging and short‑term/speculative trading; cautions on margin/pledging; no individual pledging disclosed in filings

Stock ownership guidelines for executives are not disclosed in the proxy; Schreiber does not receive extra board compensation .

Employment Terms

Term ElementDetails
Employment AgreementEffective Dec 5, 2019; amended Mar 27, 2020 (CEO transition) and Mar 12, 2021
Role StartCEO since Jan 29, 2020
Base Salary$565,600 effective Jan 1, 2025
Target Bonus50% of base salary (2025)
At‑Will EmploymentYes; 30 days’ notice by executive
Severance (no CIC)1.0x base salary; earned but unpaid prior‑year bonus + pro‑rata current‑year bonus (based on actual performance); accelerate pre‑Dec 1, 2020 equity (performance awards at target); up to 12 months COBRA
Severance (CIC window)Termination without cause or good‑reason resignation within 30 days prior to or 12 months post‑CIC: 1.5x base + 1.5x target bonus; full acceleration of all equity; up to 18 months COBRA
Triggers/DefinitionsGood Reason, Cause, Change in Control defined; 280G cut‑back or full‑pay whichever yields greater after‑tax outcome

Board Governance (Director Service, Committees, Independence)

  • Board service: Director since 2017; CEO and director (non‑independent) .
  • Committee roles: Schreiber serves on no board committees; all committees are fully independent (Audit, Compensation, Nominating) .
  • Leadership structure: Independent Chairman (Golumbeski) distinct from CEO; independent directors meet in executive session routinely .
  • Attendance: Board met eight times in 2024; all directors met at least 75% attendance; six directors attended the 2024 annual meeting .

Investment Implications

  • Pay‑for‑performance alignment: 2024 bonus paid at 60% of target tied to achievement against pre‑set corporate goals, indicating variable cash aligned to execution . Equity tilt increased markedly in 2024 (options $2.47M vs $0.24M in 2023), strengthening long‑term alignment but increasing dilution sensitivity .
  • Vesting and potential selling pressure: Large 2024 time‑based option (330,100 shares) begins vesting after 1 year, creating periodic vesting over 36 months; 2022 performance option requires sustained share‑price ≥ $18 for 30 days, limiting near‑term vesting unless performance improves . Exercise value depends on market price at vest; insider trading policy and pre‑clearance may temper opportunistic selling .
  • Ownership alignment: Significant founder‑level stake (6.4%) including 2.61M shares through Houghton Capital Holdings reflects high “skin‑in‑the‑game” . No pledging disclosed; company discourages pledging via policy .
  • Retention and change‑of‑control economics: Double‑trigger CIC at 1.5x salary+target bonus with full acceleration of equity likely reduces retention risk during strategic transactions while limiting windfalls absent termination .
  • Governance quality: Separation of Chair/CEO and independent committees support oversight; absence of committee roles for CEO mitigates dual‑role independence concerns .
  • Execution track record: Strategic pivot to SL‑325 and runway guidance into 2027 demonstrate decisive capital allocation; clinical progress and Phase 1 timing are near‑term catalysts .