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Raymond Pratt

Chief Medical Officer at SavaraSavara
Executive

About Raymond Pratt

Raymond Pratt, M.D., is Savara’s Chief Medical Officer, serving since November 2022; he is 74 years old as of April 1, 2025 and holds an M.D. from the University of Illinois College of Medicine with a nephrology fellowship at Walter Reed AMC, followed by academic roles at Johns Hopkins (Assistant Professor, Medicine/Nephrology) and multiple senior clinical development leadership roles in biopharma . Company pay-versus-performance disclosures note Savara’s 2022 net loss of $38.2 million and a value of initial fixed $100 investment at $125 for 2022 (indicative of TSR), while the company emphasizes that executive pay is not directly aligned to net income due to its clinical-stage lifecycle and focus on development milestones .

Past Roles

OrganizationRoleYearsStrategic Impact
Rockwell Medical (NASDAQ: RMTI)Chief Medical Officer2012–2019Led clinical medicine and development in renal indications .
Rockwell Medical (NASDAQ: RMTI)Chief Development Officer2019–2022Directed development strategy post-CMO tenure .
Shire PLC (now Takeda)VP R&D; Scientific Leader (Emerging Business & Renal); VP Global Clinical Medicine & Affairs; Head U.S. Clinical DevelopmentNot disclosedSenior R&D and clinical leadership across multiple business units .
Eisai Medical ResearchSenior Director, Clinical R&D; Head CNS & Internal Medicine Clinical DevelopmentNine yearsLed CNS/IM clinical development for nine years .
Walter Reed Army Medical CenterNephrology practice; Assistant Chief of Nephrology; Director of Dialysis Services1983–1985Operational leadership in nephrology services .
Johns Hopkins School of MedicinePhysician scientist training grant; James Shannon NIH New Investigator awardNot disclosedEarly-career research recognition .
Johns Hopkins (Dept. of Medicine & Nephrology)Assistant Professor1989–1993Academic leadership in medicine and nephrology .

External Roles

OrganizationRoleYearsStrategic Impact
XORTX Therapeutics (NASDAQ: XRTX)DirectorSince Dec 2021Board oversight at kidney disease-focused biotech .

Fixed Compensation

Metric20222023 (Targets)
Base Salary ($)$470,000 $470,000 (implied by 40% target bonus of $188,000)
Target Bonus (%)40% 40%
Target Bonus ($)$216,300 (full-year target; pro-rated for 2022 tenure) $188,000
Actual Bonus Paid ($)$26,268 (pro-rated) Not disclosed

Performance Compensation

MetricWeighting2022 Target2022 Actual2022 PayoutVesting/Timing
Activate all IMPALA-2 targeted sites by end of May 202210% Milestone completionAchieved (companywide goals met at 100%) 100% of corporate component Annual cash incentive
Achieve 50% IMPALA-2 enrollment by end of July 202225% Milestone completionAchieved 100% Annual cash incentive
On-track to full enrollment on planned timeline (year-end)25% Milestone completionAchieved 100% Annual cash incentive
Identify second drug product manufacturing site & two release testing sites (year-end)10% Milestone completionAchieved 100% Annual cash incentive
Establish GEMA drug substance process at 2nd site (year-end)10% Milestone completionAchieved 100% Annual cash incentive
Launch U.S. aPAP market awareness campaign by Q3 20225% Milestone completionAchieved 100% Annual cash incentive
Initiate regulatory preparedness work by Q2 20225% Milestone completionAchieved 100% Annual cash incentive
Operate within 5% of 2022 approved budget5% Budget adherenceAchieved 100% Annual cash incentive
Complete debt refinancing by Q2 20225% Milestone completionAchieved 100% Annual cash incentive

Equity Awards (Grants and Vesting)

Grant DateAward TypeShares/UnitsExercise Price ($/sh)Grant-Date Fair Value ($)Vesting
11/10/2022Stock Options375,000 $1.51 $392,300.63 16 equal quarterly installments from 11/10/2022
11/10/2022RSUs150,000 N/A$214,500 Full vest on 11/10/2024
FY 2022 Outstanding (as of 12/31/2022)Shares Not VestedMarket Value ($)
RSUs (11/10/2022 grant)150,000 $155,000 (based on 12/31/2022 price)

Equity Ownership & Alignment

MetricApr 10, 2023Apr 8, 2024
Shares Beneficially Owned50,375 (<1%) 153,125 (<1%)
Within 60 Days: options/RSUs exercisable/vesting46,875 143,125
  • Hedging and pledging of Savara securities are prohibited under company policy, supporting alignment and reducing financing risk; margin purchases are also prohibited .

Employment Terms

SituationCash SeveranceHealth BenefitsEquity AccelerationBonus Treatment
Termination without cause / resignation for good reason (outside change-of-control period)12 months base salary COBRA reimbursements up to 12 months Accelerated vesting equal to 12 months of would-have-vested equity Pro-rated portion of target bonus for days employed
Death or disability (outside change-of-control period)12 months base salary COBRA reimbursements up to 12 months Same as above Pro-rated target bonus
Termination without cause / resignation for good reason (during change-of-control period)18 months base salary Taxable lump sum equal to 18 months COBRA premiums 100% acceleration of equity awards 100% of target bonus + pro-rated target bonus
Single-trigger CIC benefitsNot provided by the Company

Quantitative Change-in-Control Economics (as of 12/31/2022)

ComponentQualifying Termination (Outside CIC)Qualifying Termination (During CIC)
Cash Severance (Salary + Bonus) ($)$496,268 $919,268
Health Insurance ($)$21,408 $32,112
Accelerated Equity ($)$11,250 $277,500
Accrued Vacation ($)
Total ($)$528,926 $1,228,880

Compensation Structure Analysis

  • 2022 pay mix shows material equity grants at hire (375k options, 150k RSUs), consistent with retention emphasis and long-term value alignment; annual cash bonus for 2022 was pro-rated and paid against corporate goals met at 100% .
  • The compensation program relies on milestone-based operational targets (trial enrollment, manufacturing readiness, regulatory preparedness, capital management), with discretionary elements rather than formulaic revenue/EBITDA metrics given clinical-stage status .
  • Company policies prohibit option repricing without shareholder approval and include no tax gross-ups in the equity plan, limiting shareholder-unfriendly practices .

Say-On-Pay & Peer Group

  • 2022 say-on-pay approval: ~92% support, indicating strong shareholder acceptance of the program at that time .
  • Peer benchmarking uses life sciences survey data and evolving biotech peer groups to calibrate competitiveness; peer group was refined in 2021–2022 to better match market cap and organizational complexity .

Investment Implications

  • Alignment: Prohibition on hedging/pledging, plus sizable unvested equity from late-2022 grants, support alignment and retention incentives through 2024 vest events .
  • Retention risk: Severance includes 12–18 months salary and bonus components with equity acceleration, reducing voluntary departure risk; the absence of single-trigger CIC mitigates windfall risk while ensuring protection upon double-trigger CIC .
  • Performance signaling: Bonus metrics emphasize execution milestones (trial progress, manufacturing, regulatory readiness, capital discipline); 2022 companywide goals at 100% support execution credibility, though financial outcomes (net loss) are not used for pay calibration per disclosures .
  • Trading signals: Upcoming vesting cliffs (RSUs on 11/10/2024) can create potential insider selling windows; however, insider trading policy constraints and blackout periods apply, and pledging is banned, moderating selling pressure risk .