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Heidy King-Jones

Chief Legal Officer and Corporate Secretary at Spyre Therapeutics
Executive

About Heidy King-Jones

Heidy King‑Jones is Chief Legal Officer and Corporate Secretary at Spyre Therapeutics (SYRE), serving since September 2023. She is 42 and holds a J.D. and LL.M in International and Comparative Law from Cornell Law School and a B.A. from Dartmouth College . During her tenure, Spyre highlighted transformation-driven value creation (market cap rising from sub‑$50M at merger close in June 2023 to well over $1.0B by end‑2023 and through 2024) and implemented a pay-for-performance program; company TSR (from a Dec‑2021 $100 base) was $18 in 2023 and $20 in 2024, with net losses of $(338.8)M in 2023 and $(208.0)M in 2024 .

Past Roles

OrganizationRoleYearsStrategic Impact
Provention Bio, Inc.Chief Legal Officer & Corporate Secretary2020–2023Led legal during financings, Tzield approval, transition to commercial stage, and sale to Sanofi (Apr 2023)
Axcella Health Inc.SVP, General Counsel & Corporate Secretary; previously VP, Legal & Corporate Secretary2018–2020Ran corporate legal function and strategy
Sarepta Therapeutics, Inc.Senior Director, Corporate Law2013–2018Built compliance program; contracts and legal work for Exondys 51 launch; member of commercial readiness group
Ropes & Gray LLPSecurities & Public Companies practiceEarly careerCounsel to public/private issuers across pharma, utilities, tech

Fixed Compensation

ComponentDetailPeriod/DateAmount/Terms
Base salaryOffer letter initial base salaryEffective Sep 1, 2023$470,000 per year
Target annual bonus% of base salaryEffective Sep 1, 202340%
Actual bonus paidDiscretionary annual bonusFY 2023$62,700
Equity grant (inducement options)Nonqualified stock options; exercise price = FMV at grantAs soon as practicable after Sep 1, 2023Options for 1.00% of outstanding shares; 4‑year vesting

Notes: FY‑2024 named executive officers did not include Ms. King‑Jones; her 2024 salary/bonus outcomes are not disclosed in the DEF 14A .

Performance Compensation

Company executive annual bonus program design (applies to executives, including legal leadership). FY‑2024 objectives, weights, and company outcomes:

Metric CategoryWeightTarget SummaryActual OutcomePayout FactorVesting/Payment
Portfolio: Advance SPY programs60%Protocols/regulatory filings enabling SPY001/002 FIH; SPY001 FIH data release in 2024; Phase 2 UC initiation in 2025Achieved (100%)Company payout determined at 120% of target for NEOs; same design applied company‑wide Annual cash bonuses paid after year‑end; NEO payments disclosed
Platform: Advance strategic pillars25%Initiate preclinical studies; assess precision medicine; delivery device strategy and partnersAchieved (100%)120% See above
Corporate: Build Spyre as IBD leader15%IR, Finance, HR, Compliance, Legal, IP maturationAchieved (100%)120% See above
Stretch: Phase 2 readiness+10%Early SPY002 IND and Phase 2 UC readinessAchieved (100%)Included in 120% factor See above
Stretch: Corporate collaboration/investment+10%Validating partnership/collaborationAchieved (100%)Included in 120% factor See above

Company disclosed FY‑2024 NEO bonuses at 120% of target; Ms. King‑Jones’s individual payout is not disclosed in the DEF 14A .

Equity Ownership & Alignment

  • Beneficial ownership: The FY‑2025 proxy lists directors and NEOs individually; Ms. King‑Jones is not itemized in the beneficial ownership table, and her individual share/option counts are not disclosed there .
  • 2023 equity awards: Ms. King‑Jones received option awards with grant date fair value of $6,356,857 in FY‑2023 (as disclosed in the registration filings) .
  • Inducement options: Equal to 1.00% of outstanding shares at grant; exercise price set at fair market value; 4‑year vesting (offer letter) .
  • Hedging/derivatives: Company policy prohibits short‑term trading, short sales, publicly traded options/derivatives, and hedging transactions .
  • Pledging: No explicit pledging prohibition disclosed; no pledging by Ms. King‑Jones disclosed .

Employment Terms

TermDetail
Start date and roleJoined Spyre as Chief Legal Officer & Corporate Secretary in September 2023
Contract & restrictive covenantsExecutives are party to standard employee invention assignment, confidentiality, non‑competition, and non‑solicit agreements; company uses offer letters defining pay and equity
Severance/change‑in‑controlCompany discloses NEO severance and CIC terms (salary, bonus, COBRA, equity acceleration); Ms. King‑Jones’s specific severance economics are not disclosed in the proxy
Clawback policyNasdaq Rule 10D‑1 compliant recoupment policy for erroneously awarded incentive comp for 3 prior years; 2024 restatement review required no clawback

Investment Implications

  • Compensation alignment: Legal leadership’s bonus target (40%) and transformation‑era equity grants (notably 2023 option award value) align incentives with progress on portfolio, platform, and corporate milestones; FY‑2024 program paid 120% on stretch and core goals, signaling execution against plan .
  • Retention and selling pressure: Four‑year option vesting and inducement award sized at 1% of shares create ongoing vesting cadence; absence of disclosed pledging plus hedging prohibitions reduce misalignment risk; lack of individual 2024 holdings disclosure limits precision on near‑term sale pressure .
  • Governance risk signals: 2024 say‑on‑pay support was 62%, with shareholder concerns on goal clarity and award magnitudes; management responded with peer‑aligned, all‑options LTI in 2024 and enhanced disclosure. 2024 restatement and auditor change were addressed with a clawback review and governance processes .
  • Execution track record: Prior roles at Provention (Tzield approval, M&A) and Sarepta (Exondys 51 launch readiness) indicate strong regulatory/commercial readiness experience, supportive of Spyre’s pipeline advancement cadence .