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David Bonita

Director at Third Harmonic Bio
Board

About David Bonita

David P. Bonita, M.D., age 49, has served as an independent director of Third Harmonic Bio since July 2020 and is a member of OrbiMed Advisors LLC, where he has served in roles of increasing responsibility since 2004 . He holds an A.B. in Biological Sciences from Harvard University and a joint M.D./M.B.A. from Columbia University . The Board determined all directors other than the CEO are independent under Nasdaq rules; Dr. Bonita was re-elected as a Class III director on June 5, 2025 with 34,965,535 “For” votes, indicating strong shareholder support .

Past Roles

OrganizationRoleTenureCommittees/Impact
OrbiMed Advisors LLCMember; various roles of increasing responsibilitySince June 2004 Investor and director across multiple biopharma companies
Morgan StanleyCorporate finance analyst, healthcare investment bankingNot disclosedTransaction and financing experience
UBSCorporate finance analyst, healthcare investment bankingNot disclosedTransaction and financing experience

External Roles

OrganizationRoleTenureCommittees/Impact
Acutus Medical, Inc.DirectorCurrent Not disclosed
Ikena Oncology, Inc.DirectorCurrent Not disclosed
Prelude Therapeutics, Inc.DirectorCurrent Not disclosed
Repare Therapeutics Inc.DirectorCurrent Not disclosed
IMARA Inc.Prior DirectorPrior service (dates not disclosed) Not disclosed
Tricida, Inc.Prior DirectorPrior service (dates not disclosed) Not disclosed

Board Governance

  • Committee assignments: Compensation Committee member; the Compensation Committee is composed of Bonita, Michael Gladstone, and Mark Iwicki (Chair) .
  • Independence: Board determined all directors except the CEO are independent under SEC/Nasdaq rules .
  • Attendance: In 2024, none of the incumbent directors attended fewer than 75% of Board and committee meetings; Board held 4 meetings, Compensation Committee held 5 .
  • 2025 re-election: Bonita received 34,965,535 votes “For,” 2,799,275 “Withheld,” with broker non-votes of 5,607,546 .

Fixed Compensation

ComponentAmountNotes
Annual Director Cash Retainer$40,000 Paid quarterly in arrears
Compensation Committee Membership Fee$5,000 Member fee (Bonita is a member)
2024 Cash Fees Earned$45,000 As reported for Bonita in 2024
Chair FeesN/A for BonitaCompensation Committee chair receives $10,000; Bonita is not chair

Performance Compensation

Equity ComponentGrant/StatusTerms2024 Value
Annual Option Grant (standard policy)20,000 options at each annual meeting Vests in full at earlier of 1 year or next annual meeting; subject to continued service Not individually disclosed for Bonita in 2024
Initial Option Grant (standard policy for new directors)40,000 options Vests 1/36 monthly over 3 years; service-based vesting Not applicable to Bonita in 2024 (he joined in 2020)
2024 Option Awards (fair value)Aggregated valueAggregate grant date fair value reported$200,144
Options Outstanding (as of 12/31/2024)CountService-based vesting; outstanding awards accelerate upon Corporate Transaction (includes Dissolution) 49,917
  • No RSUs/PSUs or performance-based equity for directors are disclosed; director option vesting is time-based with acceleration upon a Corporate Transaction (including Dissolution) .

Other Directorships & Interlocks

EntityRelationship to THRDOwnership/ControlNotes
OrbiMed Private Investments VII, LP5%+ shareholder5,808,988 shares, 12.9% as of 3/31/2025 Managed by OrbiMed Advisors LLC; David Bonita is a member of OrbiMed Advisors; OrbiMed and Bonita disclaim beneficial ownership except to pecuniary interest
Atlas Venture Funds5%+ shareholder10,432,203 shares, 23.1% as of 3/31/2025 Atlas Venture partner Michael Gladstone is a THRD director; Atlas Venture’s structure detailed in filing
  • Related-party policy: Any transaction ≥$120,000 with directors/5% holders requires Audit Committee approval; evaluated for arm’s-length terms and extent of related person’s interest .

Expertise & Qualifications

  • Capital markets and healthcare investing expertise from OrbiMed, with transaction experience at Morgan Stanley and UBS .
  • Advanced scientific and business training (M.D./M.B.A.) and biological sciences background .
  • Multi-company board experience across clinical-stage biopharma, relevant to compensation oversight and strategic evaluation .

Equity Ownership

HolderCommon Shares Owned (as of 3/31/2025)PercentOptions/Derivatives
David P. Bonita, M.D.— (less than 1%) * (<1%) 49,917 stock options outstanding as of 12/31/2024
Anti-hedging policyProhibits hedging/monetization (e.g., collars, forward sale contracts) and exchange fund contributions

Note: The company’s Insider Trading Policy prohibits hedging; pledging is not specifically referenced in the excerpt provided .

Governance Assessment

  • Board effectiveness: Bonita contributes capital allocation and sector expertise on the Compensation Committee, which engages independent consultants (Compensia and later Alpine Rewards) and operates without management conflicts; consultants’ independence assessed with no conflicts found .
  • Independence and attendance: Board determined him independent; 2024 attendance met ≥75% threshold; re-elected with strong support in 2025 .
  • Compensation and alignment: Director pay is modest cash ($45,000 in 2024) plus time-based options ($200,144 fair value; 49,917 outstanding), with option acceleration upon Corporate Transaction (including Dissolution), aligning incentives to corporate outcomes but not to specific performance metrics .
  • Potential conflicts/RED FLAGS:
    • Affiliation with a 12.9% shareholder (OrbiMed) while serving on the Compensation Committee may raise perceived conflict concerns for minority investors, even though the Board affirms independence under Nasdaq rules and OrbiMed/Bonita disclaim beneficial ownership of fund-held shares beyond pecuniary interest .
    • Limited direct common stock ownership by Bonita (less than 1%) could weaken “skin-in-the-game” perception versus option-based exposure; however, option holdings and OrbiMed’s material stake provide indirect alignment with shareholder value .
  • Controls and policies: Robust related-party transaction review via Audit Committee ; company maintains an executive Compensation Recovery Policy (clawback) under Rule 10D-1, strengthening governance norms, though primarily applicable to executives .
  • Shareholder context: As an emerging growth/smaller reporting company, THRD is not required to hold say-on-pay votes, limiting direct investor feedback on compensation design .

Overall, Bonita’s investment and board experience is accretive to compensation oversight and strategic decisions; the OrbiMed affiliation warrants continuous monitoring of Compensation Committee decisions for perceived conflicts, and his low direct share ownership suggests option-based alignment rather than substantial common stock exposure .