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Mitchell Glass

Chief Medical Officer at TNFA
Executive
Board

About Mitchell Glass

Mitchell Glass, M.D. (age 73) is TNF Pharmaceuticals’ President and Chief Medical Officer since June 13, 2024 and a director since April 8, 2024, with prior senior roles at ICI/Zeneca (led Accolate), SmithKline Beecham (COREG, TEVETEN), AtheroGenics (AGI-1067), Aqumen Pharma (CEO/CMO), and Invion (led de‑merger to Chronic Airway Therapeutics); he graduated from the University of Chicago and is board‑certified in internal medicine, pulmonary and critical care medicine . Company pay-versus-performance shows cumulative TSR dropped to $29 on a $100 initial investment in 2024 and net loss of $27.2M, framing headwinds during his first partial year as PEO . The Board currently separates Chair and PEO roles (Chair: Joshua Silverman; PEO: Mitchell Glass) .

Past Roles

OrganizationRoleYearsStrategic Impact
ICI/ZenecaDirector of Pulmonary TherapeuticsFrom 1988Led global development and submission of Accolate (first successful antileukotriene for asthma)
SmithKline BeechamVice President/DirectorFrom Mar 1995Led global portfolio in CV/respiratory/renal/metabolic; development for COREG (heart failure) and TEVETEN (hypertension)
AtheroGenics (AGIX)CMO & VP Clinical Dev/Reg Affairs1998–2003Led AGI1067 from IND to Phase 3; IPO team member
University City Science CenterChief Scientific Officer2005–2006Oversight of 54 early-stage companies
Aqumen Pharma KK & NADirector (KK); CEO/CMO (NA)2006–2011Led ophthalmic portfolio to successful U.S. marketing
Invion Plc (ASX: IVN)CMO & Director2011–2019Led de‑merger into Chronic Airway Therapeutics; nadolol POC in smokers with bronchitis

External Roles

OrganizationRoleYearsStrategic Impact
Chronic Airway TherapeuticsChief Executive OfficerCurrentRespiratory therapeutics leadership; nadolol program track record
ACCOLADE Pharma LLCChairman & CEOCurrentPortfolio stewardship (legacy antileukotriene domain)
Broom Street AssociatesPrincipalCurrentAdvisory/investment activities
OrphageniX Inc.DirectorSince 2008Gene-editing company governance
AVATAR BiotechnologiesDirectorSince 2008Biosimilars company governance

Fixed Compensation

Metric2024
Base Salary ($)175,833
Bonus ($)
All Other Compensation ($)6,500 (board fees for 2024)
NotesAppointed President & CMO on Jun 13, 2024; not entitled to additional compensation for serving as President & CMO per proxy disclosure

Performance Compensation

MetricWeightingTargetActualPayoutVesting
Stock awards (RSUs/PSUs)
Options
NotesNo stock awards or option grants disclosed for Mitchell Glass in 2024; outstanding equity awards table shows none . Company’s 2021 Equity Incentive Plan permits performance-based awards, but no Glass-specific metrics disclosed .

Equity Ownership & Alignment

As ofBeneficial Shares (Common)% of ClassOptions (Exercisable in 60 days)RSUs UnvestedPledged SharesNotes
Oct 18, 2024Not disclosedGlass not listed with beneficial ownership at Oct 18, 2024 (table shows “—”)
Mar 25, 2025Not disclosedGlass not listed with beneficial ownership at Mar 25, 2025 (table shows “—”)
  • Anti-hedging/anti-pledging policy: Company has no policy restricting hedging or pledging by employees/directors .
  • Director fees policy: Non-executive directors historically $8,000/month; reduced in Nov 2023 to $60,000 with deferrals for going-concern reasons (not directly applicable to executive directors) .

Employment Terms

  • Appointment: Director since Apr 8, 2024; President & Chief Medical Officer since Jun 13, 2024 .
  • Compensation structure: 2024 cash salary only; no bonus, no option/stock awards disclosed; proxy states Glass not entitled to additional compensation for serving as President & CMO .
  • Severance/change-of-control: No Glass-specific employment agreement, severance multiple, change-of-control triggers, or tax gross-up terms disclosed in the proxy; comparable terms provided only for other NEOs (e.g., Chapman severance) .
  • Clawback: 2021 Plan allows recoupment per any company clawback policy (if adopted), but no specific application to Glass disclosed .

Board Governance

  • Board service history: Director since Apr 8, 2024; up for election with other nominees; Board size reduced from 7 to 6 in May 2025 .
  • Committee roles: None; Glass is not listed as a member of Audit, Compensation, Nominating & Governance, or Risk & Disclosure committees .
  • Independence status: Proxy states Glass is an “independent director” under Nasdaq rules as of Apr 21, 2025, despite being an executive officer (President & CMO), which raises independence concerns; 2024 proxy did not list Glass as independent .
  • Board leadership: Roles separated—Chairman (Joshua Silverman, independent) and PEO (Glass) .
  • Attendance: Each director attended ≥75% of Board/committee meetings in 2024 .
  • Executive sessions: Independent director executive sessions policy active in prior periods (≥4 per year until July 21, 2024) .

Director Compensation

Item20232024
Glass – Fees earned (cash)N/A6,500
Standard director fees (non-executive)$8,000/month pre‑Nov 2023 Reduced to $60,000/year with deferred excess amounts from Nov 13, 2023
Equity grants to directorsOct 14, 2021 RSUs (market‑cap milestones); none vested as of Dec 31, 2024

Performance & Track Record

  • Achievements: Led Accolate (antileukotriene), COREG and TEVETEN programs; AGI1067 through Phase 3; oversight of 54 start-ups; Aqumen ophthalmic portfolio to successful U.S. market; Invion de‑merger and nadolol POC in smokers with bronchitis .
  • Company TSR and net loss context: 2024 cumulative TSR value $29 (from $100 base); net loss $27.2M; prior years show TSR volatility and sustained losses, signaling financing and execution challenges during broader turnaround .
  • Nasdaq listing risk: Received minimum bid price deficiency letter on Mar 17, 2025; reverse split proposal (1‑for‑2 to 1‑for‑100) approved for flexibility to regain compliance .

Compensation Structure Analysis

  • Cash vs equity mix: For Glass in 2024, compensation entirely cash salary plus small director fees; no equity awards granted—low direct equity alignment .
  • At‑risk pay: No disclosed performance bonus or equity; at‑risk pay appears minimal for Glass in 2024 .
  • Equity award policies: Company’s 2021 Plan permits performance awards across numerous metrics (EBITDA, TSR, etc.), but no Glass-specific performance grants disclosed; RSUs granted in 2021 tied to market-cap milestones remain unvested .
  • Clawback and repricing: Plan includes clawback references and prohibits option/SAR repricing without shareholder approval .

Risk Indicators & Red Flags

  • Independence designation: Classifying an executive officer (Glass) as an independent director under Nasdaq rules is atypical and raises governance/independence concerns .
  • Anti-hedging/pledging: No corporate policy restricting hedging/pledging—misalignment risk if insiders hedge or pledge (no Glass-specific activity disclosed) .
  • Going concern pressures: Director fee reductions and deferrals in Nov 2023 due to going-concern constraints; sustained net losses .
  • Listing status: Nasdaq bid-price deficiency and need for reverse split—potential dilution and shareholder value impact .

Say‑on‑Pay & Shareholder Feedback

  • Frequency: Triennial say‑on‑pay; next vote expected in 2026 .

Compensation Committee Analysis

  • Composition (2025): Joshua Silverman (Chair), Jude Uzonwanne; Craig Eagle departing post‑meeting .
  • Consultants: Compensation Committee did not engage consultants in 2024; limited formal activity noted .

Equity Ownership & Alignment – Detailed Table

HolderCommon Shares% CommonPreferred HoldingsWarrants/Notes
Mitchell GlassNot listed among beneficial owners (as of Oct 18, 2024 and Mar 25, 2025)

Vesting Schedules and Insider Selling Pressure

  • Outstanding awards (Glass): None shown; thus, limited near‑term vesting or selling pressure from equity awards .
  • Company‑wide RSUs (Oct 14, 2021): Vest upon market‑cap milestones sustained for 20 consecutive trading sessions; none vested by Dec 31, 2024 .

Employment Contracts, Severance & Change‑of‑Control

  • Glass: No employment agreement terms (severance multiple, change‑of‑control triggers, single/double trigger, tax gross‑ups) are disclosed in the proxy; statement indicates no additional compensation for his executive service .
  • Reference (other NEOs): Chapman severance included cash payments, COBRA reimbursement, and option acceleration; illustrative of company practices but not applicable to Glass .

Investment Implications

  • Alignment: Absence of Glass equity grants and beneficial ownership implies low direct “skin in the game”; combined with no anti‑hedging/pledging policy, alignment could be improved via performance‑based equity awards tied to clinical/regulatory milestones or TSR .
  • Governance risk: Independence designation for an executive officer and lack of committee roles for Glass suggest oversight may rely heavily on other independent directors; monitor potential changes to independence status and committee participation post‑meeting .
  • Liquidity/Listing: Bid‑price deficiency and planned reverse split introduce dilution/volatility risk; execution against capital plan and clinical catalysts will be critical to sustain listing and attract long‑term investors .
  • Pay‑for‑performance: The company’s 2021 plan permits rigorous metrics, but no Glass‑specific performance awards disclosed; instituting PSUs with explicit targets (EBITDA, TSR, clinical endpoints) could support retention and confidence signals .
  • Retention risk: With predominantly cash pay and no disclosed severance/change‑of‑control economics for Glass, retention levers appear limited; watch for future contract filings (8‑K 5.02/DEF 14A) that may add retention and performance‑linked equity .