Mitchell Glass
About Mitchell Glass
Mitchell Glass, M.D. (age 73) is TNF Pharmaceuticals’ President and Chief Medical Officer since June 13, 2024 and a director since April 8, 2024, with prior senior roles at ICI/Zeneca (led Accolate), SmithKline Beecham (COREG, TEVETEN), AtheroGenics (AGI-1067), Aqumen Pharma (CEO/CMO), and Invion (led de‑merger to Chronic Airway Therapeutics); he graduated from the University of Chicago and is board‑certified in internal medicine, pulmonary and critical care medicine . Company pay-versus-performance shows cumulative TSR dropped to $29 on a $100 initial investment in 2024 and net loss of $27.2M, framing headwinds during his first partial year as PEO . The Board currently separates Chair and PEO roles (Chair: Joshua Silverman; PEO: Mitchell Glass) .
Past Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| ICI/Zeneca | Director of Pulmonary Therapeutics | From 1988 | Led global development and submission of Accolate (first successful antileukotriene for asthma) |
| SmithKline Beecham | Vice President/Director | From Mar 1995 | Led global portfolio in CV/respiratory/renal/metabolic; development for COREG (heart failure) and TEVETEN (hypertension) |
| AtheroGenics (AGIX) | CMO & VP Clinical Dev/Reg Affairs | 1998–2003 | Led AGI1067 from IND to Phase 3; IPO team member |
| University City Science Center | Chief Scientific Officer | 2005–2006 | Oversight of 54 early-stage companies |
| Aqumen Pharma KK & NA | Director (KK); CEO/CMO (NA) | 2006–2011 | Led ophthalmic portfolio to successful U.S. marketing |
| Invion Plc (ASX: IVN) | CMO & Director | 2011–2019 | Led de‑merger into Chronic Airway Therapeutics; nadolol POC in smokers with bronchitis |
External Roles
| Organization | Role | Years | Strategic Impact |
|---|---|---|---|
| Chronic Airway Therapeutics | Chief Executive Officer | Current | Respiratory therapeutics leadership; nadolol program track record |
| ACCOLADE Pharma LLC | Chairman & CEO | Current | Portfolio stewardship (legacy antileukotriene domain) |
| Broom Street Associates | Principal | Current | Advisory/investment activities |
| OrphageniX Inc. | Director | Since 2008 | Gene-editing company governance |
| AVATAR Biotechnologies | Director | Since 2008 | Biosimilars company governance |
Fixed Compensation
| Metric | 2024 |
|---|---|
| Base Salary ($) | 175,833 |
| Bonus ($) | — |
| All Other Compensation ($) | 6,500 (board fees for 2024) |
| Notes | Appointed President & CMO on Jun 13, 2024; not entitled to additional compensation for serving as President & CMO per proxy disclosure |
Performance Compensation
| Metric | Weighting | Target | Actual | Payout | Vesting |
|---|---|---|---|---|---|
| Stock awards (RSUs/PSUs) | — | — | — | — | — |
| Options | — | — | — | — | — |
| Notes | No stock awards or option grants disclosed for Mitchell Glass in 2024; outstanding equity awards table shows none . Company’s 2021 Equity Incentive Plan permits performance-based awards, but no Glass-specific metrics disclosed . |
Equity Ownership & Alignment
| As of | Beneficial Shares (Common) | % of Class | Options (Exercisable in 60 days) | RSUs Unvested | Pledged Shares | Notes |
|---|---|---|---|---|---|---|
| Oct 18, 2024 | — | — | — | — | Not disclosed | Glass not listed with beneficial ownership at Oct 18, 2024 (table shows “—”) |
| Mar 25, 2025 | — | — | — | — | Not disclosed | Glass not listed with beneficial ownership at Mar 25, 2025 (table shows “—”) |
- Anti-hedging/anti-pledging policy: Company has no policy restricting hedging or pledging by employees/directors .
- Director fees policy: Non-executive directors historically $8,000/month; reduced in Nov 2023 to $60,000 with deferrals for going-concern reasons (not directly applicable to executive directors) .
Employment Terms
- Appointment: Director since Apr 8, 2024; President & Chief Medical Officer since Jun 13, 2024 .
- Compensation structure: 2024 cash salary only; no bonus, no option/stock awards disclosed; proxy states Glass not entitled to additional compensation for serving as President & CMO .
- Severance/change-of-control: No Glass-specific employment agreement, severance multiple, change-of-control triggers, or tax gross-up terms disclosed in the proxy; comparable terms provided only for other NEOs (e.g., Chapman severance) .
- Clawback: 2021 Plan allows recoupment per any company clawback policy (if adopted), but no specific application to Glass disclosed .
Board Governance
- Board service history: Director since Apr 8, 2024; up for election with other nominees; Board size reduced from 7 to 6 in May 2025 .
- Committee roles: None; Glass is not listed as a member of Audit, Compensation, Nominating & Governance, or Risk & Disclosure committees .
- Independence status: Proxy states Glass is an “independent director” under Nasdaq rules as of Apr 21, 2025, despite being an executive officer (President & CMO), which raises independence concerns; 2024 proxy did not list Glass as independent .
- Board leadership: Roles separated—Chairman (Joshua Silverman, independent) and PEO (Glass) .
- Attendance: Each director attended ≥75% of Board/committee meetings in 2024 .
- Executive sessions: Independent director executive sessions policy active in prior periods (≥4 per year until July 21, 2024) .
Director Compensation
| Item | 2023 | 2024 |
|---|---|---|
| Glass – Fees earned (cash) | N/A | 6,500 |
| Standard director fees (non-executive) | $8,000/month pre‑Nov 2023 | Reduced to $60,000/year with deferred excess amounts from Nov 13, 2023 |
| Equity grants to directors | Oct 14, 2021 RSUs (market‑cap milestones); none vested as of Dec 31, 2024 | — |
Performance & Track Record
- Achievements: Led Accolate (antileukotriene), COREG and TEVETEN programs; AGI1067 through Phase 3; oversight of 54 start-ups; Aqumen ophthalmic portfolio to successful U.S. market; Invion de‑merger and nadolol POC in smokers with bronchitis .
- Company TSR and net loss context: 2024 cumulative TSR value $29 (from $100 base); net loss $27.2M; prior years show TSR volatility and sustained losses, signaling financing and execution challenges during broader turnaround .
- Nasdaq listing risk: Received minimum bid price deficiency letter on Mar 17, 2025; reverse split proposal (1‑for‑2 to 1‑for‑100) approved for flexibility to regain compliance .
Compensation Structure Analysis
- Cash vs equity mix: For Glass in 2024, compensation entirely cash salary plus small director fees; no equity awards granted—low direct equity alignment .
- At‑risk pay: No disclosed performance bonus or equity; at‑risk pay appears minimal for Glass in 2024 .
- Equity award policies: Company’s 2021 Plan permits performance awards across numerous metrics (EBITDA, TSR, etc.), but no Glass-specific performance grants disclosed; RSUs granted in 2021 tied to market-cap milestones remain unvested .
- Clawback and repricing: Plan includes clawback references and prohibits option/SAR repricing without shareholder approval .
Risk Indicators & Red Flags
- Independence designation: Classifying an executive officer (Glass) as an independent director under Nasdaq rules is atypical and raises governance/independence concerns .
- Anti-hedging/pledging: No corporate policy restricting hedging/pledging—misalignment risk if insiders hedge or pledge (no Glass-specific activity disclosed) .
- Going concern pressures: Director fee reductions and deferrals in Nov 2023 due to going-concern constraints; sustained net losses .
- Listing status: Nasdaq bid-price deficiency and need for reverse split—potential dilution and shareholder value impact .
Say‑on‑Pay & Shareholder Feedback
- Frequency: Triennial say‑on‑pay; next vote expected in 2026 .
Compensation Committee Analysis
- Composition (2025): Joshua Silverman (Chair), Jude Uzonwanne; Craig Eagle departing post‑meeting .
- Consultants: Compensation Committee did not engage consultants in 2024; limited formal activity noted .
Equity Ownership & Alignment – Detailed Table
| Holder | Common Shares | % Common | Preferred Holdings | Warrants/Notes |
|---|---|---|---|---|
| Mitchell Glass | — | — | — | Not listed among beneficial owners (as of Oct 18, 2024 and Mar 25, 2025) |
Vesting Schedules and Insider Selling Pressure
- Outstanding awards (Glass): None shown; thus, limited near‑term vesting or selling pressure from equity awards .
- Company‑wide RSUs (Oct 14, 2021): Vest upon market‑cap milestones sustained for 20 consecutive trading sessions; none vested by Dec 31, 2024 .
Employment Contracts, Severance & Change‑of‑Control
- Glass: No employment agreement terms (severance multiple, change‑of‑control triggers, single/double trigger, tax gross‑ups) are disclosed in the proxy; statement indicates no additional compensation for his executive service .
- Reference (other NEOs): Chapman severance included cash payments, COBRA reimbursement, and option acceleration; illustrative of company practices but not applicable to Glass .
Investment Implications
- Alignment: Absence of Glass equity grants and beneficial ownership implies low direct “skin in the game”; combined with no anti‑hedging/pledging policy, alignment could be improved via performance‑based equity awards tied to clinical/regulatory milestones or TSR .
- Governance risk: Independence designation for an executive officer and lack of committee roles for Glass suggest oversight may rely heavily on other independent directors; monitor potential changes to independence status and committee participation post‑meeting .
- Liquidity/Listing: Bid‑price deficiency and planned reverse split introduce dilution/volatility risk; execution against capital plan and clinical catalysts will be critical to sustain listing and attract long‑term investors .
- Pay‑for‑performance: The company’s 2021 plan permits rigorous metrics, but no Glass‑specific performance awards disclosed; instituting PSUs with explicit targets (EBITDA, TSR, clinical endpoints) could support retention and confidence signals .
- Retention risk: With predominantly cash pay and no disclosed severance/change‑of‑control economics for Glass, retention levers appear limited; watch for future contract filings (8‑K 5.02/DEF 14A) that may add retention and performance‑linked equity .