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Farrell Simon

Chief Commercial Officer at Trevi Therapeutics
Executive

About Farrell Simon

Farrell Simon is Chief Commercial Officer at Trevi Therapeutics (TRVI), serving in the role since February 2023, after joining Trevi in September 2020; he holds both an MBA and Pharm.D. from the University of Florida and previously led commercial and strategy roles at Pfizer and Procter & Gamble . Company performance during his tenure included strong total shareholder return (TSR) through 2024, reflecting significant equity value creation for investors . He contributed directly to commercialization planning and payer/prescriber dynamics for Haduvio across idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC) indications, including public discussion of scheduling risk and market access strategy .

Metric20232024
Total Shareholder Return – $100 initial value$69.43 $213.47
Net Income (Loss) ($MM)$(29.07) $(47.91)

Past Roles

OrganizationRoleYearsStrategic Impact
Trevi TherapeuticsChief Commercial OfficerFeb 2023–Present Leads commercial strategy and launch planning for Haduvio; active in market access/scheduling risk communications
Trevi TherapeuticsSVP, Head of Commercial & StrategyFeb 2022–Feb 2023 Built integrated commercial strategy pre-launch; cross-functional leadership
Trevi TherapeuticsVP, Head of US MarketingSep 2020–Feb 2022 Established US marketing capabilities ahead of pivotal data
Pfizer Inc.Senior Director, Chief of Staff to Biopharma Group PresidentJan 2018–Sep 2020 Member of biopharma executive leadership team; enterprise commercial coordination
Procter & GambleGeneral management, marketing, medical affairsNot disclosed Brand and medical affairs foundation for later biopharma leadership

External Roles

OrganizationRoleYearsNotes
The Simon Cancer FoundationFounder & CEONot disclosed Philanthropic leadership
Greater New Haven Chamber of CommerceBoard of DirectorsCurrent Regional economic development engagement
University of Florida – Business School & College of PharmacyAdvisory Board MemberPreviously held Academic advisory roles

Fixed Compensation

  • Base salary, target bonus %, and actual bonus for Simon are not disclosed in the proxy; company policy targets executive base salaries at ~50th percentile and sets annual bonuses against weighted corporate goals (2024 corporate performance score 110%) .
  • Trevi generally uses stock options (not RSUs/SARs) for executives, granting time-based and performance-based options; the company had no RSUs outstanding as of March 31, 2025 .

Performance Compensation

MetricWeightingTargetActualPayoutVesting Dates
RIVER trial success (RCC Phase 2a) tied to Simon’s performance-based stock option (120,000 sh grant, Feb 15, 2024)Not disclosedSuccessful results certified by Comp CommitteeTrial met primary endpoint; committee certified RIVER metrics Mar 10, 2025 38,400 shares vested from the performance option Certified Mar 10, 2025
CORAL trial success (IPF chronic cough Phase 2b)Not disclosedSuccessful results certificationNot yet certified as of Mar 10, 2025Eligible for additional vesting upon CORAL success Not disclosed
  • Standard executive time-based option vesting schedule is 25% at 1-year post grant; remaining 75% monthly over 36 months .

Equity Ownership & Alignment

ItemDetail
Total shares owned (post-transactions)76,900 shares as of March 10, 2025
Ownership as % of shares outstanding~0.076% of 101,744,767 outstanding (Apr 23, 2025)
Insider sale activity (selling pressure)Sold 81,313 shares on Mar 10, 2025 at $6.7276–$7.1498 per share; exercised options totaling 112,563 shares at strikes $0.511–$3.91; remaining direct holdings 76,900 shares
10b5-1 PlanTransactions conducted under a Rule 10b5-1 trading plan, per media summary referencing SEC filing
Hedging/pledgingCompany Insider Trading Policy prohibits short sales and hedging/derivative transactions; pledging not disclosed
Ownership guidelinesNo formal executive stock ownership guidelines

Insider Transactions Detail (Mar 10, 2025):

DateTypeSharesPriceAfter-Ownership
03/10/2025Option exercise17,500$3.21 63,150
03/10/2025Option exercise63,813$3.91 126,963
03/10/2025Option exercise31,250$0.511 158,213
03/10/2025Sale76,963$6.7276 81,250
03/10/2025Sale4,350$7.1498 76,900

Employment Terms

TermDetails
Employment natureAt-will; executives sign standard non-compete, non-solicit, confidentiality, assignment-of-inventions agreements
Non-compete & non-solicitNon-compete and non-solicit during employment and for 1–2 years post-termination
Severance (no change-in-control)CCO as officer covered under Separation Benefits Plan: 6 months base salary + COBRA premium contributions if terminated without cause or resigns for good reason
Severance (change-in-control within 12 months)12 months base salary (lump sum); 1.0× target bonus (lump sum); COBRA premium contributions; 100% acceleration of time-based equity awards (performance-based awards excluded)
Clawback & award governanceEquity awards subject to clawback policy; no automatic vesting on change in control; repricing prohibited without stockholder approval; options/SARs must be at or above fair market value at grant

Compensation Structure Notes (Company-wide context applicable to CCO)

  • Equity mix: Trevi primarily uses stock options with time-based and performance-based vesting; as of March 31, 2025, no RSUs were outstanding .
  • Annual bonuses: Corporate goals with weighted metrics evaluated by the compensation committee; 2024 corporate performance score set at 110% .
  • Market positioning: Base salaries targeted at ~50th percentile; equity compensation between the 50th–75th percentile versus peer group; Alpine Rewards engaged as independent compensation consultant .
  • Equity plan: 2019 Stock Incentive Plan amended in April 2025 to add 6,000,000 shares and remove evergreen, reflecting sustained use of equity incentives while limiting automatic dilution .

Investment Implications

  • Alignment: Performance-based option vesting tied to clinical milestones (RIVER, CORAL) directly links Simon’s compensation to value-creating data readouts; vesting of 38,400 shares upon RIVER certification underscores pay-for-performance structure .
  • Selling pressure: March 2025 option exercises and sales reduced near-term ownership but were conducted under a 10b5-1 plan, tempering concerns about discretionary timing; Simon retains 76,900 shares, maintaining skin-in-the-game .
  • Retention risk: Change-in-control and severance protections (12 months base and 1.0× target bonus in CIC; 6 months severance otherwise) plus 1–2 year restrictive covenants support retention and orderly transitions, with balanced shareholder safeguards via clawback and no automatic CIC vesting .
  • Dilution and incentive capacity: 2025 equity plan amendment adds capacity for future awards and removes evergreen, aligning with stockholder oversight; continued emphasis on options (over RSUs) suggests higher at-risk equity tied to performance and tenure .
  • Execution credibility: Public commentary from Simon on scheduling and market strategy, combined with company-level TSR improvements in 2024, supports confidence in commercial execution; further vesting potential hinges on CORAL outcomes .