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Kamran Alam

Chief Financial Officer at Taysha Gene Therapies
Executive

About Kamran Alam

Kamran Alam, 47, has served as Taysha Gene Therapies’ Chief Financial Officer since August 2020 and also signs corporate filings as Corporate Secretary. He is a Certified Public Accountant with a B.B.A. from the University of Michigan (Ross) and an M.B.A. in finance from Indiana University (Kelley) . During 2024, executive bonuses were paid at 110% of corporate goal attainment versus 90% in 2023, indicating higher internal performance against objectives; Alam’s 2024 non‑equity incentive payout was $210,942 on a $455,126 salary with a 40% target bonus . As CFO, his tenure spans major financings (August 2023 $150M private placement; June/July 2024 ~$76.8M follow‑on) that extended liquidity and supported pipeline execution, and the company sought an increase in authorized shares in 2025 to preserve financing flexibility .

Past Roles

OrganizationRoleYearsStrategic impact
Rocket PharmaceuticalsSVP, Finance and Principal Financial OfficerOct 2019 – Jul 2020Senior public-company finance leadership prior to joining TSHA
AveXis, Inc.VP, FinanceApr 2016 – Oct 2019Finance leadership at a publicly traded gene therapy company later acquired by Novartis
Aptinyx Inc.Increasing roles; Senior Director, Finance & Accounting at departure2013 – Apr 2016Built finance and accounting capabilities at a public biopharma company

External Roles

OrganizationRoleYears
No external directorships disclosed for Alam .

Fixed Compensation

YearBase Salary ($)Target Bonus (% of Salary)Actual Cash Bonus ($)All Other ($)Total ($)
2024455,126 40% 210,942 10,620 2,518,777
2023413,751 40% 148,950 10,661 975,401
2022401,700 40% 136,578 9,330 1,201,823

Notes:

  • 2024 corporate goal attainment was 110% (applies to executives’ non-equity incentive plan) .
  • 2023 corporate goal attainment was 90% .

Performance Compensation

ComponentMetric(s)WeightingTargetActual/PayoutVesting/Timing
Annual incentive (2024)Corporate and individual objectivesNot disclosed40% of salary 110% company attainment; $210,942 paid Cash paid after year-end
Annual incentive (2023)Corporate and individual objectivesNot disclosed40% of salary 90% company attainment; $148,950 paid Cash paid after year-end
RSUs (grant 1/2/2024)Service-basedN/A590,413 units N/A25% annually on 1/2/2025–1/2/2028
Options (grant 1/2/2024)Service-basedN/A590,413 options @ $1.71 N/A25% on 1/2/2025; then monthly over 36 months; exp. 1/2/2034
Options (grant 12/14/2023)Service-basedN/A62,527 exerc., 125,055 unexerc. @ $0.70 N/AVests in 3 equal annual installments starting 12/31/2024

Equity Ownership & Alignment

As ofTotal Beneficial Ownership (sh)% of OutstandingCommon Stock (Direct)Options Exercisable within 60 daysRSUs Vesting within 60 days
Mar 31, 2025861,130 <1% 211,335 499,076 150,719

Additional alignment and policies:

  • Insider Trading/Hedging: Company prohibits short sales, derivative hedging, margin accounts and other speculative transactions by insiders, reducing alignment risk concerns from pledging/hedging; no pledging disclosure identified .
  • Ownership guidelines: Not disclosed in proxy -.

Recent insider transactions and selling pressure:

  • On Aug 21, 2025, Alam reported a sale of 54,491 shares executed solely as sell‑to‑cover for taxes upon RSU vesting (not a discretionary open market sale); post‑transaction beneficial ownership was 1,187,603 shares .

Outstanding and Recent Equity Awards (Vesting Schedules)

Grant DateAwardQuantityExercise PriceExpirationVesting TermsStatus/Value Reference
1/2/2024RSU590,413 25% annually on 1/2/2025–2028 Market value $1,021,414 at 12/31/2024 for these RSUs
1/2/2024Stock options590,413 unexerc. $1.71 1/1/2034 25% on 1/2/2025; remainder monthly over 36 months
12/14/2023Stock options62,527 exerc.; 125,055 unexerc. $0.70 12/13/2033 3 equal annual installments starting 12/31/2024
2/2/2023RSU9,347 25% vested 2/2/2024; then 2/2/2025–2027 $16,170 market value at 12/31/2024
2/2/2023Stock options68,704 exerc.; 81,196 unexerc. $1.18 2/1/2033 25% on 2/2/2024; remainder monthly over 36 months
2/2/2023Stock options11,423 exerc.; 13,500 unexerc. $1.18 2/1/2033 25% on 2/2/2024; remainder monthly over 36 months
4/6/2022Stock options26,666 exerc.; 13,334 unexerc. $6.52 4/5/2032 25% on 4/6/2023; remainder monthly over 36 months
2/23/2022Stock options56,666 exerc.; 23,334 unexerc. $5.96 2/22/2032 25% on 2/23/2023; remainder monthly over 36 months
1/19/2021Stock options68,541 exerc.; 1,459 unexerc. $31.00 1/18/2031 25% on 1/19/2022; remainder monthly over 36 months

Note: Market values in the table are based on $1.73 closing price at 12/31/2024 as disclosed in the proxy tables -.

Employment Terms

TopicKey terms
Start date/tenureCFO since August 2020
2024 salary and target bonusBase $455,126; target bonus 40% of salary
Severance (without cause / good reason)12 months base salary continuation; contingent on release and restrictive covenants
Change‑in‑Control (CIC) severance planOn covered termination during CIC period: lump sum salary (12 months for Alam), 100% of target annual bonus, 12 months COBRA, and full accelerated vesting of all equity (performance awards at 100% of target)
Restrictive covenantsNon‑competition and non‑solicitation obligations tied to severance benefits
Clawback policyAdopted Nov 2023; compliant with SEC/Dodd‑Frank listing rules; SOX 304 reimbursement applicable to CEO/CFO on misconduct-related restatements
Hedging/pledgingInsider policy prohibits short sales, options/hedges, and margin accounts
Pension/Deferred compNo pension/deferral programs; standard 401(k) with match; modest perquisites

Related Party/Other Governance Context

  • Capital raises: August 2023 $150.0M private placement; June 27, 2024 public offering plus July 9, 2024 greenshoe exercised; ~ $76.8M net proceeds .
  • 2025 proposal to increase authorized shares from 400M to 700M to support financing flexibility and employee retention through equity .
  • Compensation committee uses Aon as its independent consultant and oversees pay-for-performance architecture .

Compensation Structure Analysis

  • Mix shift toward RSUs in 2024: Large time‑based RSU grant (590,413 shares) paired with options increased the equity component and reduced risk compared to options‑only grants, aligning with broader biotech practices in volatile markets .
  • Variable pay sensitivity: Corporate goal attainment rose from 90% (2023) to 110% (2024), supporting higher annual incentive payouts year‑over‑year .
  • CIC acceleration: Full acceleration on all equity in a change‑in‑control is shareholder‑sensitive and increases potential transaction‑related payouts for executives .
  • Clawback and hedging policies: Formal clawback adopted in 2023 and prohibitions on hedging/margin reduce misalignment risk .
  • No evidence of option repricing or tax gross‑ups beyond nominal gift‑card gross‑up provided to employees in 2023 (Alam: $491) .

Insider Selling Pressure and Vesting Overhang

  • Recurring vest dates: RSUs granted 1/2/2024 vest 25% annually on Jan 2 (2025–2028), which may trigger sell‑to‑cover transactions around those dates .
  • Documented “sell‑to‑cover” only: Aug 21, 2025 Form 4 sale of 54,491 shares solely to satisfy taxes on vested RSUs; not a discretionary sale; post‑transaction beneficial ownership 1,187,603 shares .

Investment Implications

  • Pay-for-performance linkage: Annual incentives adjust with corporate goal attainment (110% in 2024 vs. 90% in 2023), supporting dynamic cash bonuses; the lack of disclosed metric weightings limits transparency on drivers but the program is responsive to operational outcomes .
  • Retention and overhang: Significant unvested equity (notably RSUs and options from late 2023/early 2024) suggests continued retention hooks; expect periodic sell‑to‑cover rather than discretionary selling at vest dates .
  • Change‑in‑control economics: Single‑trigger plan design at the equity level (full acceleration upon covered termination in CIC period) plus cash severance (12 months base + 100% bonus target + COBRA) could be material in M&A scenarios, aligning management and shareholder interests but adding deal‑related costs .
  • Governance/controls: Clawback adoption and hedging/margin prohibitions reduce downside governance risk; no evidence of option repricing or pledging reduces red‑flag concerns .
  • Financing acumen: Oversight of 2023–2024 capital raises and push to increase authorized shares point to a financing‑ready posture that can mitigate funding risk in pivotal development phases .

All data above are drawn from TSHA’s 2025 and 2024 DEF 14A proxy statements, the company’s 10‑K disclosures, 8‑K filings, and SEC Form 4 filings as cited.