Sign in

You're signed outSign in or to get full access.

Jason Smith

General Counsel and Chief Compliance Officer at UroGen Pharma
Executive

About Jason Smith

Jason Smith, age 53, is UroGen Pharma’s General Counsel, Chief Compliance Officer, and Corporate Secretary, serving since August 2020; he leads legal, IP, and compliance functions. He holds a B.A. in Economics (cum laude) from Binghamton University and a J.D. (with high honors) from George Washington University; prior roles include Chief Counsel, Oncology at Pfizer, legal roles at Wyeth, and associate at Howrey (antitrust/commercial litigation) . Company performance context during his tenure includes 2024 Jelmyto net product revenue of $90.4M vs. $82.7M in 2023 (12% underlying demand growth), FDA approval of Zusduri in June 2025, and 2024 net loss of $126.9M; TSR proxy disclosure shows value of a $100 investment at $93.27 (2022), $157.73 (2023), $111.99 (2024) .

Past Roles

OrganizationRoleYearsStrategic impact
Pfizer Inc.Chief Counsel, Oncology2016–2020Led legal support for oncology; senior legal leadership at a global pharma
WyethAntitrust Counsel; Global Product Counsel; Chief Counsel, U.S. PharmaceuticalsNot disclosedSupported prescription pharmaceuticals businesses in various senior legal roles
Howrey, Simon, Arnold & WhiteAssociate, Antitrust and Commercial LitigationNot disclosedLitigation and antitrust experience building foundational legal toolkit

External Roles

OrganizationRoleYearsNotes
No external directorships or board roles disclosed for Mr. Smith in the proxy

Fixed Compensation

Metric20232024
Base Salary ($)456,733 475,003
Target Bonus (% of base)50% 50%
Actual Annual Bonus Paid ($)275,808 203,179 (85% of target for 2024)

Additional 2025 one-time special bonus: $100,000 awarded June 30, 2025 for contributions to FDA approval of Zusduri .

Performance Compensation

Company-set 2024 corporate metrics (drive NEO annual bonus outcomes), results, and payout link:

MetricWeightTargetActualPayout impact
FDA acceptance of UGN-102 NDA by Oct 31, 202465%Acceptance by 10/31/24AchievedContributed positively
2024 Revenue35%$100MNot achievedReduced payout
Stretch: Exceed $100M revenue by 10%/20%/30%15% max>$110M/$120M/$130MNot achievedNo impact
Stretch: Accelerated NDA acceptance by 30/60/90 days25% maxEarly acceptance vs 10/31/24Not achievedNo impact
Stretch: Strategic partnership/BD deal20%Execute deal(s)AchievedPositive impact
  • Resulting individual payout: Mr. Smith 85% of target bonus for 2024 (target 50% of salary), paid $203,179 .
  • Program design emphasizes at-risk pay and long-term equity; no tax gross-ups; no option repricing .

Equity incentives and vesting mechanics:

  • 2024 RSUs vest in equal annual installments over 3 years (service-vesting); 2024 PSUs vest on first U.S. commercial sale of Zusduri (condition achieved in 2025) .

Equity Ownership & Alignment

Beneficial ownership and structure:

  • Total beneficial ownership: 172,180 shares (32,514 ordinary shares plus 139,666 options/RSUs vesting within 60 days) as of June 30, 2025; less than 1% of outstanding shares (46,199,134). Approximate stake ≈0.37% (172,180 / 46,199,134) .
  • Hedging/margin: Insider Trading Policy prohibits short sales, transactions in puts/calls, hedging transactions, and use of margin accounts; reduces misalignment/hedging risk .
  • Pledging: No pledging by Mr. Smith disclosed in the proxy .
  • Ownership guidelines: No executive stock ownership guidelines disclosed (proxy silent) .

Outstanding equity position (as of 12/31/2024):

InstrumentGrantedStatus at 12/31/24Key terms
Stock options (inducement)60,000Exercisable; $19.66 strike; exp. 10/1/203010/1/2020 grant; time-vested
Stock options8,000Exercisable; $22.07; exp. 1/31/20311/31/2021 grant; time-vested
Stock options15,000Exercisable; $17.98; exp. 6/5/20316/5/2021 grant; time-vested
Stock options30,00020,000 exercisable; 10,000 unexercisable; $7.72; exp. 1/31/20321/31/2022 grant; time-vested
Stock options40,00013,333 exercisable; 26,667 unexercisable; $10.39; exp. 1/31/20331/31/2023 grant; time-vested
RSUs2,500Unvested1/31/2022 grant; equal annual vesting over 3 years
RSUs13,334Unvested1/31/2023 grant; equal annual vesting over 3 years
RSUs6,667Unvested9/7/2023 grant; equal annual vesting over 3 years
RSUs16,500Unvested1/31/2024 grant; equal annual vesting over 3 years
PSUs16,500Unearned at 12/31/24; subsequently vestedVest on first U.S. commercial sale of Zusduri (achieved 2025)

Notes on moneyness (contextual): URGN closing price was $13.70 on June 30, 2025; options struck at $7.72 and $10.39 were in-the-money at that date; higher-strike grants ($17.98–$22.07–$19.66) were out-of-the-money at that date .

Employment Terms

  • Start date/tenure: Serving as GC/CCO/Corporate Secretary since August 2020 .
  • Employment status: At-will; confidentiality/IP and restrictive covenants include non-compete, non-solicitation, confidentiality (durations not specified in proxy) .
  • 2024 fixed pay: Base salary $475,003; bonus target 50% of salary .
  • Severance (non–change-in-control): If terminated without cause/for good reason/death/disability, salary continuation 6 months; prorated target bonus for year of termination (company performance-based; individual portion deemed achieved); prior-year unpaid bonus; equity vesting acceleration of 1/12th (8.33%); up to 6 months COBRA reimbursements (CEO has higher levels) .
  • Change-in-control (double trigger within 3 months prior to or 24 months after CoC): 100% accelerated vesting of all unvested equity; lump sum of 12 months base salary + 100% of target bonus; 12 months COBRA reimbursements (CEO has 18 months) .
  • Clawbacks: SOX 304 recoupment if required; Dodd-Frank/Nasdaq-compliant clawback policy adopted (Rule 10D-1; Nasdaq 5608) .
  • Hedging/short sales/margin prohibited by Insider Trading Policy .
  • Perquisites/tax gross-ups: Company states no executive fringe benefits/perks and no excise tax gross-ups .

Compensation Structure Analysis

  • Mix and performance linkage: Significant at-risk pay via annual bonus tied to FDA and commercial/BD objectives; long-term equity tilted toward RSUs/PSUs in 2024 (no 2024 option grant for Mr. Smith), increasing certainty relative to options and explicitly tying PSU vesting to Zusduri commercialization .
  • Program competitiveness: Non-CEO executive total direct compensation positioned at ~15th percentile of peers in 2024 (CEO at ~20th percentile), suggesting moderation of pay levels with strong performance linkage .
  • Policy changes expanding equity capacity: 2025 proposals increase max equity grant capacity under the officer compensation policy (officers: from 100,000 to 300,000; CEO: from 200,000 to 600,000) and add 2,750,000 shares to the 2017 Plan, enabling larger/evolving grants going forward (dilution risk but retention tool) .

Say-on-Pay & Shareholder Feedback

  • 2024 say-on-pay approval exceeded 87% of votes cast; company reports ongoing outreach to holders representing >70% of shares on executive comp and governance .

Equity Ownership & Alignment (Summary Table)

ItemValue
Beneficial shares (6/30/25)172,180 (32,514 shares + 139,666 options/RSUs within 60 days)
Shares outstanding basis46,199,134 (6/30/25)
Ownership % (approx.)~0.37% (172,180 / 46,199,134)
Hedging/short/marginProhibited under Insider Trading Policy
PledgingNo director/officer pledging disclosed for Mr. Smith
Ownership guidelinesNot disclosed for executives

Employment Contracts, Severance, and CoC Economics (Detail)

ProvisionNon-CoC TerminationChange-in-Control (double trigger)
Cash severance6 months base salary Lump sum 12 months base + 100% target bonus
Bonus treatmentProrated target bonus for year of termination (company perf-based; individual portion deemed achieved); prior-year unpaid bonus Included in lump sum (100% target bonus)
Equity acceleration1/12th (8.33%) vesting acceleration of RSUs/options 100% vesting and exercisability of all unvested equity
COBRAUp to 6 months 12 months
ClawbacksSOX 304; Dodd-Frank/Nasdaq policy adopted SOX 304; Dodd-Frank/Nasdaq policy adopted

Performance & Track Record

  • Program and milestones: FDA approved Zusduri on June 12, 2025; 2024 NDA acceptance target achieved; BD collaborations executed; Jelmyto 2024 net product revenue of $90.4M (+$7.7M YoY), though $100M core revenue goal not achieved; loan restructuring and equity raise in 2024 .
  • Pay-versus-performance context: TSR proxy series shows variability ($100 investment: $93.27 in 2022, $157.73 in 2023, $111.99 in 2024) alongside continuing net losses (2024 net loss $126.9M) .

Compensation Peer Group

  • Peer set used for benchmarking includes 2seventy bio, Arcus Biosciences, Day One, Deciphera, Eagle, Erasca, IDEAYA, Inhibrx, iTeos, Karyopharm, Kura, RAPT, Rigel, Syndax, Tango, Verastem, Xencor, Y-mAbs; positioning: non-CEO executives ~15th percentile; CEO ~20th percentile .

Risk Indicators & Red Flags

  • Hedging/margin prohibited; clawbacks in place; no option repricing; no excise tax gross-ups; company states no executive perquisites .
  • 2025 special bonus ($100k) for FDA approval contributions aligns with milestone achievement; continue monitoring for any outsized discretionary awards vs. policy .
  • Equity plan share increase and higher officer grant caps raise dilution risk; balanced by retention needs and governance guardrails (no liberal share recycling; no single-trigger CoC acceleration) .

Investment Implications

  • Alignment and execution: Mr. Smith’s incentive design (PSUs tied to Zusduri first sale; RSUs vesting over 3 years) closely aligns with regulatory and commercialization milestones; 2025 vesting of PSUs suggests potential incremental insider supply—monitor Form 4s around vesting and trading windows for near-term flow signals .
  • Retention risk: Double-trigger CoC with full acceleration and 12 months cash/benefits is market-consistent, lowering transaction friction; non-CoC severance (6 months + partial vesting) provides baseline retention while limiting windfalls .
  • Pay moderation vs. market: Non-CEO executive comp positioned ~15th percentile indicates cost discipline; however, approved increases to officer equity grant ceilings plus added share pool could lift future equity awards—track burn rate and overhang (company disclosed overhang/burn controls) .
  • Governance and shareholder sentiment: 87% say-on-pay support and active outreach reduce governance overhang; hedging/margin prohibitions and clawbacks strengthen alignment .
  • Financial context: Continued net losses and revenue goals shortfall offset by regulatory win and BD progress; watch 2025–2026 Zusduri sales targets embedded in officer PSU design for ongoing pay-for-performance validation .