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Paul Sekhri

Paul Sekhri

President and Chief Executive Officer at vTv TherapeuticsvTv Therapeutics
CEO
Executive
Board

About Paul Sekhri

Paul Sekhri, 66, is Chairman, President and Chief Executive Officer of vTv Therapeutics. He has served as CEO since August 1, 2022 and as a director since August 9, 2022; he was appointed Chairman in March 2024 . He holds a B.S. from the University of Maryland and completed postgraduate studies in clinical anatomy and neuroscience there . Under his tenure, the FDA lifted the clinical hold on cadisegliatin and the company moved to reinitiate Phase 3 activities, while continuing to operate as a smaller reporting company with scaled disclosures and ongoing losses .

Performance context (company-level):

  • vTv’s Pay vs Performance table shows total shareholder return (TSR) value of a $100 initial investment of $65.00 (2022), $28.19 (2023), and $33.85 (2024), alongside net losses of $(19.164) million, $(20.250) million, and $(18.462) million, respectively .
MetricFY 2022FY 2023FY 2024
vTv TSR ($100 initial investment)$65.00 $28.19 $33.85
Net Loss (USD mm)$(19.164) $(20.250) $(18.462)

Past Roles

OrganizationRoleYearsStrategic Impact / Notes
eGenesis, Inc.President & CEOJan 2019 – Apr 2022Led a clinical-stage biotech; executive experience before joining vTv
Lycera CorporationPresident & CEOFeb 2015 – Jan 2019Ran immunology-focused biotech prior to eGenesis
TPG BiotechHead, Biotechnology Operating GroupNot disclosedPrivate equity/VC operating leadership in life sciences
Sanofi; Teva; ARIAD; NovartisSenior leadership rolesNot disclosedGlobal pharma operating and BD experience
Cerimon PharmaceuticalsFounder & CEONot disclosedCompany founding/operating experience

External Roles

EntityCapacityNotes
Compugen Ltd.Chairman of the BoardCurrent
Resolution Therapeutics, Ltd.Chairman of the BoardCurrent
Kaerus BioscienceChairman of the BoardCurrent
Veeva Systems Inc.DirectorCurrent
AdhereTech; LikemindsDirectorCurrent
PhilanthropyTrustee/AdvisoryMetropolitan Opera; Advisory Council of NY Philharmonic; Chairman of Young Concert Artists, Inc.

Fixed Compensation

  • Base salary was “not less than” $480,000 under the 7/25/2022 employment agreement; in February 2024, his base salary was increased to $650,000 and his target bonus reduced to 60% of base salary .
  • As reported compensation actually paid in fiscal years:
Component (USD)FY 2023FY 2024
Salary$480,000 $621,666
All Other Compensation (401k match + life insurance)$20,913 (=$9,900 + $11,013) $20,160 (=$10,350 + $9,810)

Notes:

  • vTv uses smaller reporting company scaled disclosures, limiting detail on compensation metrics .
  • Mr. Sekhri does not receive compensation for board service .

Performance Compensation

  • Annual cash incentive: Target set at 60% of base salary beginning February 2024; payouts tied to achievement of performance targets (metrics not itemized in proxy due to scaled disclosure) .
  • Equity incentive: Options with multi-year vesting (details below).
Incentive (USD)FY 2023FY 2024
Non-Equity Incentive Plan Compensation (cash bonus)$831,042 (earned/paid timing as disclosed) $273,000 (earned in 2024, paid 2025)
Option Awards (Grant Date Fair Value)$2,949,001 (includes awards made in 2025 for 2024 performance per SEC rules)

Equity grant and vesting detail (CEO holdings):

  • Inducement option award: 55,000 options at $31.61 (7/26/2022); vesting 25% at first anniversary, remaining 75% vesting quarterly over the next three years; subject to potential acceleration upon specified performance metrics .
  • 2024 award: Options granted 2/27/2024 at $11.81, vesting in equal quarterly installments over three years .
GrantVesting Status @ 12/31/2024StrikeExpiration
7/26/2022 (Inducement)30,938 exercisable / 24,062 unexercisable $31.61 7/26/2032
2/27/202422,303 exercisable / 66,909 unexercisable $11.81 2/27/2034

Pay versus Performance (company-reported “Compensation Actually Paid” for PEO vs TSR and net loss):

  • PEO CAP: $1,615,434 (2022), $697,403 (2023), $1,978,633 (2024); TSR and net losses as in the “About” table above .

Equity Ownership & Alignment

  • Beneficial ownership (as of April 1, 2025): 79,986 shares, or 2.45% of outstanding on an as-converted basis; includes 5,000 Class A shares held directly and options to purchase up to 74,986 shares vested or vesting within 60 days .
  • Outstanding options detail (as of 12/31/2024): 53,241 exercisable and 90,971 unexercisable across two grants (see table above) .
  • Pledging/hedging: vTv’s trading policy prohibits short sales and trading in public options/derivatives, requires pre-clearance for insiders, and imposes blackout periods; no pledging by Mr. Sekhri is disclosed in the beneficial ownership table .

Employment Terms

Key terms from the 7/25/2022 Employment Agreement (as amended by subsequent salary/bonus changes):

  • Base salary and bonus: Base “not less than” $480,000; increased to $650,000 in Feb 2024; target bonus set at 60% of base .
  • Equity: Inducement option award to purchase 55,000 shares at $31.61 with 4-year vesting schedule (25% at year 1, then quarterly) and potential acceleration on specified performance .
  • Severance (termination without cause / resignation for good reason): 12 months base salary paid in installments, continuation of COBRA coverage for 12 months on the same cost-sharing basis (subject to tax law constraints), and payment of target cash bonus for the year of termination (release required) .
  • Change-in-control (double-trigger): If terminated without cause or for good reason within 12 months following a change in control, severance increases to 18 months of base salary (with the other severance components above) .
  • Restrictive covenants: Two-year post-employment non-compete and two-year non-solicit; standard confidentiality/IP and non-disparagement provisions .

Board Governance

  • Board service: Director since August 2022; Executive Chair since March 2024 .
  • Committee structure and independence: Audit (Spiegelman, Chair; Akkaraju; Phillips), Compensation (Phillips, Chair; Cheong; Al Marzooqi), Nominating & Corporate Governance (Cheong, Chair; Spiegelman). The independent directors are Drs. Akkaraju, Cheong, Al Marzooqi, Phillips, and Mr. Spiegelman; Mr. Sekhri serves as CEO and is not independent .
  • Special voting procedures: For three years from Feb 27, 2024, at least five directors must approve certain major actions (e.g., M&A, significant financings). Termination of the CEO or appointment of a different CEO requires the vote of four directors, excluding the CEO .
  • Board activity: Seven meetings in 2024; all directors attended at least 94% of board and committee meetings .

Investment Implications

  • Alignment and incentives: A meaningful portion of compensation is equity-based with multi-year vesting (including large 2024 awards), and Mr. Sekhri beneficially owns 2.45% (largely option-based), aligning him with shareholders over time .
  • Vesting and trading: Quarterly vesting schedules on recent options create potential periodic liquidity events; however, insider trading controls (pre-clearance, blackout periods, and prohibitions on short sales/derivatives) govern timing and method of any sales .
  • Retention risk vs protections: Contractual protections (12–18 months’ salary, COBRA, and target bonus upon qualifying terminations) and a 2-year non-compete/non-solicit reduce near-term turnover risk; change-in-control economics are double-triggered, moderating windfall concerns .
  • Governance checks on CEO/Chair dual-role: Independent committee leadership and a special voting requirement—four directors (excluding the CEO) to remove the CEO—provide counterweights to the combined role .
  • Execution track record and catalysts: Under Sekhri, the FDA lifted the clinical hold and CATT1 screening was reinitiated—key operational milestones toward advancing cadisegliatin; near-term outcomes hinge on timely trial execution and financing capacity .
  • Financial risk: The company remains pre-revenue with persistent net losses and disclosed substantial doubt about going concern, implying elevated financing and dilution risk despite recent operational progress .

Appendix: Additional Compensation and Performance Tables

Compensation Summary (Selected CEO line items)

Metric (USD)FY 2023FY 2024
Salary$480,000 $621,666
Non-Equity Incentive Plan Compensation$831,042 $273,000
Option Awards (Grant-Date Fair Value)$2,949,001
All Other Compensation$20,913 $20,160

Outstanding Equity Awards (as of 12/31/2024)

GrantExercisableUnexercisableExercise PriceExpiration
7/26/2022 Inducement30,938 24,062 $31.61 7/26/2032
2/27/2024 Award22,303 66,909 $11.81 2/27/2034

Beneficial Ownership (as of 4/1/2025)

HolderShares Beneficially Owned% of Outstanding
Paul Sekhri79,986 (incl. 5,000 Class A directly; 74,986 options vested/vesting within 60 days) 2.45% (as-converted base)

Pay vs Performance (PEO “Compensation Actually Paid”)

MetricFY 2022FY 2023FY 2024
PEO Compensation Actually Paid (USD)$1,615,434 $697,403 $1,978,633
TSR ($100 initial investment)$65.00 $28.19 $33.85
Net Loss (USD mm)$(19.164) $(20.250) $(18.462)