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Catherine Mackey

Director at Voyager TherapeuticsVoyager Therapeutics
Board

About Catherine J. Mackey, Ph.D.

Independent director at Voyager Therapeutics (VYGR) since August 2022; age 69 as of the April 7, 2025 record date . She holds a B.S. and Ph.D. in microbiology from Cornell University and led R&D and operations at Pfizer Global Research & Development (SVP; Director, La Jolla Labs) from 2001–2010, bringing >30 years’ biotech leadership to Voyager . The Board determined she is independent (all current members except the CEO and a 5% holder’s designee) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Pfizer Global R&D; Pfizer La Jolla LabsSVP; Director, La Jolla Labs2001–2010Led biotech R&D/operations; senior leadership experience
Cour PharmaceuticalsChair of the BoardMay 2014–Dec 2022Governance/oversight through clinical-stage immunomodulation
GW Pharmaceuticals plcDirectorDec 2017–May 2021 (acquired by Jazz)Board governance at a commercial biotech
Poseida Therapeutics, Inc.DirectorJan 2019–Jun 2021Board governance at cell/gene therapy company
Trillium Therapeutics Inc.DirectorJun–Nov 2021 (acquired by Pfizer)Governance in oncology; transaction experience
Avid Bioservices, Inc.DirectorJul 2019–Feb 2025 (acquired by GHO/Ampersand)CDMO oversight; board experience through acquisition

External Roles

OrganizationRoleTenureNotes
IDEAYA Biosciences, Inc. (public)DirectorSince Apr 2022Current public company board; oncology focus

Board Governance

  • Committee memberships: Audit Committee member; Science & Technology Committee member (not a chair) .
  • Compensation Committee and Nominating & Corporate Governance Committee: not a member .
  • Attendance: Directors regularly hold executive sessions; each director attended ≥75% of Board and relevant committee meetings in 2024; directors attended the 2024 annual meeting .
  • Independence: Independent director (Board determined all current members except Alfred Sandrock and Jude Onyia are independent) .

Fixed Compensation (Non‑Employee Director; 2024)

ComponentAmount (USD)Detail
Annual Board cash retainer$40,000Per policy
Audit Committee member fee$8,000Per policy
Science & Technology Committee member fee$5,000Per policy
Total cash fees (reported)$53,000Sum of retainers/fees

Policy context (for all directors): Chairman $72,500; non‑employee members $40,000; Audit Chair $16,000/member $8,000; Compensation Chair $12,500/member $6,000; Science & Tech Chair $10,000/member $5,000; Nominating Chair $10,000/member $5,000 .

Performance Compensation (Equity; 2024–2025)

Item2024 GrantVesting/TermsNotes
Stock option grant (annual) – grant date fair value$144,000Annual option up to 24,000 shares; vests in full by earlier of 1-year anniversary or next annual meeting
Initial option grant (on joining Board)Policy up to 48,000 sharesVests quarterly over four years (time-based)
Non-employee director annual grant (2025 planned)24,000 shares eachPer “New Plan Benefits” table for directors as a group
Change-in-control protectionDouble triggerIf awards assumed, full vesting upon termination without cause within 12 months of sale event; if not assumed, time-based awards fully vest at sale event
Annual non‑employee director comp cap$750,000 (incumbent); $782,500 (Chair); $1,000,000 initial year2025 Stock Incentive Plan limit (grant-date value plus cash)

Performance metrics: Director equity awards are time-based (options); no director‑specific revenue/EBITDA/ESG hurdles disclosed. Clawback: Participants in the 2025 Plan agree to be bound by any Company clawback policy; Company adopted a Nasdaq‑compliant compensation recovery policy effective Oct 2, 2023 (primarily covering executive officers) .

Other Directorships & Interlocks

CompanySectorOverlap/Interlock risk with VYGR
IDEAYA Biosciences, Inc.OncologyNo disclosed related‑party transactions or supplier/customer ties with Voyager

No family relationships among directors/executives; related-party context at Voyager primarily involves Neurocrine Biosciences as a >5% holder and collaboration counterparty; Neurocrine’s designee (Dr. Onyia) is on the Board. No disclosure of Mackey-related party transactions with Voyager .

Expertise & Qualifications

  • Senior leadership in large pharma (Pfizer) and multiple public/private biotech boards; deep R&D and operations background .
  • Scientific credentials (Cornell Ph.D. in microbiology); >30 years biotech experience; contributes to Science & Technology Committee oversight .

Equity Ownership

MetricValue
Total beneficial ownership (shares)76,250 (all options counted as exercisable or vesting within 60 days of Apr 7, 2025)
Ownership % of common shares outstanding<1% (55,313,413 shares outstanding)
Options held (as of 12/31/2024)90,000 options (aggregate)
Vested vs. near-term vesting (as of Apr 7, 2025)76,250 options counted in beneficial ownership; 26,750 vest within 60 days of record date
Pledging/HedgingCompany policy prohibits hedging/pledging (limited exceptions); officers/directors subject to the policy

Governance Assessment

  • Board effectiveness: Mackey brings senior R&D operating experience, serves on Audit and Science & Technology, enhancing technical oversight and financial discipline. Attendance and independence disclosures support engagement and investor-aligned governance .
  • Alignment: Cash fees are modest; equity is time-based with clear vesting and capped director compensation under the 2025 Plan; change-of-control terms are shareholder-friendly (no automatic vesting; double-trigger acceleration) .
  • Conflicts: No Mackey-specific related party or shared business dealings disclosed; broader Neurocrine agreement introduces one designated director (not Mackey), with standstill/voting restrictions and conditions, mitigating influence risks .
  • Signals: 95% say-on-pay approval in 2024 indicates positive shareholder sentiment toward Voyager’s compensation governance framework; Audit Committee independence and expertise maintained; use of an independent compensation consultant (Aon) and defined peer group suggests disciplined compensation oversight, though Mackey is not on that committee .

RED FLAGS: None disclosed for Mackey regarding low attendance, related-party transactions, hedging/pledging, or option repricing. Equity awards are time-based; no underwater-option repricing authority without shareholder approval under the new plan .