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Patrick LePore

Lead Independent Director at VYNE Therapeutics
Board

About Patrick LePore

Patrick LePore, age 70, is VYNE’s Lead Independent Director and a Class III director; he has served on the Board since September 2020 and was appointed Lead Independent Director in February 2021. He is an experienced pharmaceutical executive, formerly Chairman, CEO and President of Par Pharmaceutical, and founder of Boron, LePore & Associates (took public in 1997; later sold to Cardinal Health). He holds a bachelor’s degree from Villanova University and an MBA from Fairleigh Dickinson University; he is classified as independent under Nasdaq rules.

Past Roles

OrganizationRoleTenureCommittees/Impact
Par Pharmaceutical Companies, Inc.Chairman, CEO & President2006–2012; remained Chairman after sale to TPG; led sale to Endo in 2015Led strategic transactions, including sale processes
Boron, LePore & AssociatesFounder; CEOTook public in 1997; later soldBuilt and exited medical communications firm; strategic execution track record
Hoffmann-La RocheEarly career rolesNot disclosedPharma industry foundation

External Roles

OrganizationRoleStatus/Timing
Lannett Company, Inc.Chairman of the BoardWithin past five years (proxy disclosure)
Matinas BioPharma Holdings, Inc.DirectorWithin past five years
PharMerica CorporationDirectorWithin past five years
Innoviva, Inc.DirectorWithin past five years
Villanova UniversityTrustee (prior)Prior service noted

Board Governance

  • Independence: VYNE’s Board determined all directors other than the CEO are independent; LePore is independent and serves as Lead Independent Director (since Feb 2021). The Board adopted a lead independent structure to strengthen independence and governance.
  • Committee assignments: Chair, Nominating & Corporate Governance Committee; member: Nominating & Corporate Governance Committee. Not listed on Audit or Compensation Committees.
  • Attendance and engagement: In FY2024, the Board met 6 times; Audit (4), Compensation (2), Nominating & Governance (1). Each director attended at least 75% of aggregate Board and committee meetings; all directors attended the 2024 annual meeting.
  • Anti-hedging/pledging: Directors are prohibited from margin accounts, pledging, short sales, and hedging transactions in VYNE stock.

Fixed Compensation

ComponentPolicy Amount2024 Actual (LePore)
Annual cash retainer$40,000$70,575 (includes role/committee fees)
Lead Independent Director fee$25,000Included in cash earned
Committee chair fee (Nominating & Governance)$10,000 (chair inclusive of member fee)Included in cash earned

Notes:

  • Non-employee directors receive committee member fees: Audit ($10,000), Compensation ($7,500), Nominating & Governance ($5,000); chair fees are inclusive at Audit ($20,000), Compensation ($15,000), Nominating & Governance ($10,000). Additional $25,000 for Lead Independent Director.
  • LePore’s 2024 cash fees totaled $70,575.

Performance Compensation

Equity Award DetailGrant DateShares/UnitsExercise PriceVestingGrant-Date Fair Value / 2024 Equity Comp
Annual director option grantDec 12, 202420,000 options$2.40Vests 1-year from grantIncluded in 2024 option awards
One-time director option grantJan 1, 202420,000 optionsNot disclosed (policy-based)Vested Jan 1, 2025Rationale: underwater equity; low ownership vs peers
2024 Option Awards (LePore)2024$76,200 (ASC 718)

Key features:

  • Annual grant sizing: options representing 0.046% of shares outstanding (inclusive of pre-funded warrants) at the annual meeting; initial grants upon appointment equal 2× annual grant size. Options have a 10-year term and vest per policy.
  • Change-of-control: Unvested director equity fully vests immediately prior to effective date if continuous service at that time.

Other Directorships & Interlocks

CompanySector/NotesPotential Interlocks
Lannett (generics), Matinas BioPharma (biotech), PharMerica (pharmacy services), Innoviva (respiratory/royalty mgmt)Pharma/biotech breadth; governance and transaction experienceNo VYNE-related transactions disclosed; network breadth may aid partnering

Expertise & Qualifications

  • Senior pharma operator and dealmaker: Led Par through private equity and strategic sales; founded and IPO’d Boron, LePore & Associates; deep governance experience.
  • Education: BA, Villanova; MBA, Fairleigh Dickinson University.
  • Governance roles: Lead Independent Director; Chair, Nominating & Corporate Governance Committee.

Equity Ownership

HolderTotal Beneficial Ownership% of Shares OutstandingComposition
Patrick LePore94,373 shares<1% of class51,472 common; 42,901 options exercisable within 60 days of Oct 15, 2025

Reference base: 33,043,619 shares outstanding (Oct 15, 2025).

Governance Assessment

  • Strengths

    • Independent leadership: LePore as Lead Independent Director enhances oversight and independent board leadership.
    • Committee alignment: Chairs Nominating & Governance; independence affirmed; clear committee chartering and Nasdaq/SEC compliance across committees.
    • Attendance: Compliance with ≥75% attendance threshold; directors attended the annual meeting, indicating engagement.
    • Risk-alignment policies: Prohibition on pledging and hedging; clawbacks adopted (Dodd-Frank-compliant, plus broader misconduct triggers for executives).
  • Watch items / potential red flags

    • One-time option grants to all directors (except one) to address underwater awards and ownership gaps; while rationale is peer alignment, recurring “catch-up” equity could be perceived as pay inflation if repeated. Monitor future grant cadence and dilution.
    • Change-of-control full vesting for directors’ equity awards can be viewed as generous; evaluate alignment vs market norms given micro-cap context.
    • Related-party transactions: Policy is robust; no specific transactions involving LePore identified in reviewed sections—continue monitoring for any interlocks with prior employers or portfolio companies.
  • Compensation mix and alignment

    • 2024 director pay for LePore: Cash $70,575; equity $76,200; policy-driven annual grants plus role-based cash fees, with LID premium enhancing responsibility-based pay rather than meeting fees.
    • Ownership: <1% stake; options outstanding provide equity sensitivity; company aimed to boost executive and director ownership relative to peers in recent grant cycles.
  • Board operations

    • Meeting cadence appears appropriate for a clinical-stage biotech; ensure executive-session practices and succession planning are robust (not disclosed).

Overall: LePore’s independent leadership, prior CEO/chair experience, and governance chair role support board effectiveness. Pay structure blends role-based cash with options; watch for repeated extraordinary equity actions and maintain scrutiny on change-of-control vesting terms and any emergent related-party exposures.