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John Shannon

John Shannon

Chief Executive Officer at Xeris Biopharma HoldingsXeris Biopharma Holdings
CEO
Executive
Board

About John Shannon

John Shannon, age 63, has served as Chief Executive Officer and a director of Xeris Biopharma since August 2024, after serving as President and COO from October 2021 to August 2024; he joined Xeris in 2017 as COO and holds a B.S. in Biology (microbiology emphasis) from Western Illinois University . Under his tenure and prior leadership roles, Xeris has highlighted strong revenue momentum: 2023 total revenue reached $163.9 million and exceeded internal goals , Q2’24 revenue was anticipated to exceed $47 million (+23% YoY) , Q1’25 revenue grew 48% YoY to $60.1 million (Recorlev +141% YoY) , and 2025 revenue guidance is $260–$275 million with a commitment to remaining adjusted EBITDA positive . The 2024 say‑on‑pay received ~89.6% support, signaling broad investor approval of pay design .

Past Roles

OrganizationRoleYearsStrategic impact
Xeris BiopharmaCEO and DirectorAug 2024–presentCEO/board leadership following internal succession; continued execution on growth
Xeris BiopharmaPresident & COOOct 2021–Aug 2024Led operations during Strongbridge integration; positioned for CEO transition
Xeris Pharmaceuticals, Inc.COO; later also PresidentFeb 2017–Aug 2020 (COO); Aug 2020–Oct 2021 (President)Built commercial/operational platform ahead of holdco formation
Catheter Connections, Inc.CEO and Director2015–2016 (to acquisition)CEO/board role through sale of the company
Durata TherapeuticsChief Commercial Officer2012–2014 (to acquisition)Led commercial strategy until acquisition
Baxter BioScienceVP & General Manager2002–2012Senior P&L/operations roles in biopharma

External Roles

OrganizationRoleYearsStrategic impact
Catheter Connections, Inc.Director (in addition to CEO role)2015–2016Board oversight through company sale

Fixed Compensation

YearBase Salary ($)Target Bonus (% of salary)Actual Bonus Paid ($)
2024629,193 CEO target 65% effective Aug 1, 2024; prior target 50% before promotion 433,475 (includes prorated amounts across roles)
2023571,411 50% 343,949
2022549,433 275,600

Notes:

  • Effective on appointment to CEO (Aug 1, 2024), base salary was set to $680,000 and target annual incentive increased to 65% of salary .
  • 2024 annual incentive for the CEO was 120% of target (corporate achievement 110% plus +10% recognition), prorated for pre‑promotion period .

Performance Compensation

Annual cash incentive (2024) design and payout:

ComponentMetric(s)WeightingTargetActual/ScorePayout Mechanics
Corporate objectives (CEO)Profitability, growth, innovation, enterprise development, people100% (CEO award fully corporate) 100%110% corporate achievement; Committee added +10% for leadership in transition → 120% payout CEO payout = corporate result (plus 10% recognition for 2024)

Equity awards granted in 2024:

Grant DateInstrumentShares/Units (#)Exercise/Base Price ($)VestingGrant Date Fair Value ($)
1/31/2024RSUs750,000 Time‑based; vests in three equal annual installments 1,845,000
8/1/2024RSUs250,000 Time‑based; vests in three equal annual installments 607,500
8/1/2024SARs (cash‑settled)300,000 2.43 Cliff vests in full on 2nd anniversary; settles in cash 309,037

Equity Ownership & Alignment

As ofTotal Beneficial Ownership (#)% of Shares OutstandingComponents
April 14, 20251,315,638 <1% (out of 156,384,578 shares) 887,118 common shares; 428,520 options exercisable within 60 days

Additional alignment policies:

  • Anti‑hedging and pledging: Company policy prohibits hedging and prohibits any pledging of company securities by directors and officers .
  • Director stock ownership guidelines: Non‑employee directors must attain holdings equal to 3x annual cash retainer within 5 years; all non‑employee directors were compliant or within the grace period as of Dec 31, 2024 .
  • Executive pay mix: Target pay mix highlights 82% variable “at‑risk” for CEO (illustrative mix disclosed), aligning pay with performance .

Vesting supply considerations:

  • RSUs vest in equal annual installments over three years from each grant date (i.e., anticipated vesting events in 2025–2027 for both January and August 2024 RSU grants) .
  • SARs vest and automatically exercise on the second anniversary (August 1, 2026) and settle in cash, which limits open‑market selling pressure from this award .

Employment Terms

TermKey Provision
Status/TermAt‑will; second amended and restated employment agreement effective Aug 1, 2024 .
Base/Target BonusBase salary $680,000; target annual incentive 65% of salary .
Severance (non‑CIC)1.5x salary+target bonus; pro‑rata bonus; up to 18 months COBRA reimbursement; installments per payroll; subject to release .
Severance (CIC within 12 months)2.0x salary+target bonus (paid in lump sum per proxy); pro‑rata bonus; 18 months COBRA; outplacement up to 3 months; time‑based equity vests immediately; option exercise window to earlier of expiry or 24 months; subject to release .
Estimated payouts (as of 12/31/24)Non‑CIC: $1,682,110 total; CIC termination: $7,885,521 total (includes RSU acceleration $5,367,499; SARs $288,000; healthcare $50,110; other perqs $3,912) .
ClawbackIncentive compensation recoupment policy for accounting restatements .
Hedging/PledgingProhibited for all directors/officers/employees .
Non‑compete/Non‑solicitEmployment agreements reaffirm confidentiality, IP assignment, non‑compete and non‑solicit obligations (restrictive covenants) .

Board Governance

  • Role: Director (Class III); term expires at the 2027 annual meeting; CEO since Aug 2024 .
  • Board leadership: Independent Chair (Marla S. Persky) since Aug 2024, separating Chair/CEO roles and mitigating dual‑role concerns .
  • Committees: Audit (Kong, Persky, Schmid→Brady as incoming chair), Compensation (Bormann [chair], Halkuff, Schmid, Sherman), Nominating & Corporate Governance (Halkuff [chair], Bormann, Johnson, Persky, Sherman); CEO is not listed on standing committees .
  • Attendance: Board met 7 times in 2024; all directors attended ≥75% of applicable meetings except one director (Dr. Sherman) who attended 71% .

Performance & Track Record

Period/ContextHighlight
2023 executionCorporate objectives largely exceeded; revenue $163.9m at top of guidance; strong cash position; 120% corporate achievement for bonus .
CEO transition (2024)CEO succession announced with Q2’24 revenue anticipated >$47m (+23% YoY); Board cited “solid financial position” and strong growth .
Q1 2025 resultsTotal revenue $60.1m (+48% YoY); Recorlev +141% YoY; tightened 2025 revenue guidance to $260–$275m; commitment to adjusted EBITDA positivity .

Say‑on‑Pay, Peer Practices, and Governance

  • Say‑on‑Pay: 2024 proposal received ~89.6% support; committee determined no material changes were necessary at that time .
  • Consultant/peer input: Compensation Committee engages Aon and references peer data in setting pay (including 2024 promotion terms) .
  • Practices: Double‑trigger CIC; no excise tax gross‑ups; no hedging/pledging; no option/SAR repricing without shareholder approval; majority of pay is at‑risk .

Compensation Structure Analysis

  • Cash versus equity mix: CEO pay is predominantly variable (82% at‑risk), balancing annual cash incentives with multi‑year RSUs and SARs to align with long‑term value creation .
  • Shift in equity vehicles: 2024 promotion added time‑based RSUs and cash‑settled SARs; no PSUs disclosed, which reduces performance‑contingent risk relative to options/PSUs but maintains retention and stock‑price linkage .
  • Performance linkage: Annual incentives tied to corporate strategic objectives (profitability, growth, innovation, enterprise development, people); CEO payout entirely corporate, with targeted adjustments for leadership in transition (10% in 2024) .
  • Risk controls: Robust clawback; anti‑hedging/pledging; no repricing; independent chair and independent committees provide oversight .

Equity Ownership & Selling Pressure Outlook

  • Beneficial ownership: 1,315,638 shares (<1%), including 428,520 options exercisable within 60 days of April 14, 2025 .
  • Upcoming vesting cadence: RSUs from Jan 31, 2024 (750k) and Aug 1, 2024 (250k) vest in equal annual tranches over three years (2025–2027), implying recurring vesting events; SARs (300k) vest in Aug 2026 and settle in cash (no share sales) .
  • Pledging/hedging: Prohibited, reducing risk of forced or hedged share sales .

Employment & Contracts

  • Severance design: CEO severance elevated relative to other NEOs (1.5x non‑CIC, 2.0x CIC) with pro‑rata bonus and healthcare continuation; double‑trigger equity acceleration enhances retention but also increases CIC costs .
  • Quantified CIC exposure: As of 12/31/24, estimated CEO CIC package ~$7.89m primarily due to equity acceleration, with non‑CIC ~$1.68m .
  • Restrictive covenants: Confidentiality, IP assignment, non‑compete and non‑solicit reaffirmed in employment agreements .

Board Service (Director‑Specific)

  • Class/tenure: Class III director since Aug 2024; term through 2027 .
  • Independence: CEO‑director status raises standard independence considerations; mitigated by having an independent Chair since Aug 2024 .
  • Committees: Not listed as a member of Audit, Compensation, or Nominating & Corporate Governance in the proxy’s committee rosters .
  • Attendance: Board‑level attendance expectations met by all but one director in 2024; board met 7 times .

Investment Implications

  • Alignment: High at‑risk pay (82% for CEO) and corporate‑objective‑based annual incentives support pay‑for‑performance; anti‑hedging/pledging and a clawback strengthen alignment and risk management .
  • Near‑term supply: RSU tranches from 2024 awards vest annually through 2027, creating periodic potential selling windows; SARs are cash‑settled (no direct share supply) .
  • Retention/CIC: Elevated CEO severance (1.5x/2.0x) and double‑trigger equity acceleration improve retention but increase CIC transaction costs; as of 12/31/24, estimated CIC value ~$7.9m largely from equity acceleration .
  • Execution/growth: Company is guiding to $260–$275m 2025 revenue with adjusted EBITDA positivity; strong Q1’25 growth and Recorlev acceleration bolster credibility of operating plan under Shannon .
  • Governance: Separation of Chair/CEO and independent committees mitigate CEO‑director independence concerns; 2024 SoP support (~89.6%) indicates investor acceptance of the current pay framework .