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Paul Clancy

Chair of the Board at Xilio Therapeutics
Board

About Paul J. Clancy

Paul J. Clancy, age 63, has served on Xilio’s board since July 2020 and as independent Chair of the Board since June 2022. He brings 35+ years of financial management and strategic planning experience, including CFO roles at Alexion (2017–2019) and Biogen (since 2007), preceded by finance/strategy positions at PepsiCo; he holds a B.S. from Babson College and an MBA from Columbia Business School and is a Senior Visiting Lecturer of Finance at Cornell University’s Graduate School of Business .

Past Roles

OrganizationRoleTenureCommittees/Impact
Alexion PharmaceuticalsEVP, Senior AdvisorNov 2019 – Jul 2020Senior advisory following CFO tenure
Alexion PharmaceuticalsChief Financial OfficerJul 2017 – Oct 2019Led finance during biopharma scale-up
Biogen (Biogen Idec)EVP & CFOSince 2007 (prior roles since 2001)Led treasury, tax, IR, business planning; prior VP portfolio management; VP U.S. marketing
PepsiCoFinance/Strategy/GM roles13 years (prior to 2001)Multifunctional finance and strategy experience

External Roles

OrganizationRoleTenureNotes
Sionna TherapeuticsChair of the BoardCurrentPublic biopharma board leadership
Incyte CorporationDirectorCurrentPublic pharmaceutical company
Exact Sciences CorporationDirectorCurrentPublic cancer diagnostics company
Agios PharmaceuticalsDirectorSep 2013 – Jun 2023Public pharma board service
Cornell University (Graduate School of Business)Senior Visiting Lecturer of FinanceCurrentAcademic appointment

Board Governance

  • Board leadership: Independent Chair of the Board; Class III director; committee member on Compensation; not listed on Audit or Nominating/Corporate Governance .
  • Committee composition: Compensation Committee members are Christina Rossi (Chair), Paul Clancy, and Robert Ross, M.D.; met 3 times in 2024 . Audit Committee (Bonstein—Chair, Brennan, Rossi) met 5 times in 2024; Nominating/Corporate Governance (Curran—Chair, Shannon, Xu) met 2 times in 2024 .
  • Independence: Board determined all directors except CEO René Russo are independent under Nasdaq and Exchange Act rules; Clancy is independent .
  • Attendance: The full board met 7 times in 2024; each director attended at least 75% of board and applicable committee meetings .

Fixed Compensation

ComponentPolicy/ActualAmountNotes
Annual cash retainer (non-employee director)Policy effective Apr 14, 2025$40,000Chair of Board retainer $70,000
Audit Committee memberPolicy$7,500Chair $15,000
Compensation Committee memberPolicy$5,000Chair $10,000
Nominating & Corporate Governance memberPolicy$4,000Chair $8,000
Fees earned in cash (Paul Clancy, 2024)Actual$70,000Reflects Chair role

Performance Compensation

ComponentYearGrant/MetricAmount/UnitsVesting/Notes
Stock options (grant-date fair value)2024Option awards (ASC 718)$19,058Aggregate option holdings detailed below
Initial director option grantPolicyNew director grant under 2021 Plan62,000 optionsGranted upon initial election (for new directors)
  • No RSUs/PSUs, performance share metrics, or meeting fees are disclosed for non-employee directors; compensation is cash retainers/committee fees plus stock options .
  • Xilio’s special-meeting proposals in Oct 2025 covered employee option repricing and a 2025 Stock Incentive Plan; non-employee directors are explicitly excluded from repricing and the 2025 Plan participation, mitigating director self-compensation risk .

Other Directorships & Interlocks

CompanySectorRolePotential Interlock/Conflict Notes
Sionna TherapeuticsBiopharmaChairNo Xilio-related related-party transactions disclosed; monitor any overlapping partnerships
Incyte CorporationPharmaDirectorLarge-cap pharma; no Xilio RPTs disclosed
Exact SciencesDiagnosticsDirectorDiagnostics; no Xilio RPTs disclosed
Agios Pharmaceuticals (former)PharmaDirector (former)Historical role; no current RPTs

Expertise & Qualifications

  • Extensive CFO and finance leadership at Alexion and Biogen; deep experience overseeing treasury, tax, investor relations, business planning .
  • Board leadership across multiple public companies and biopharma domain expertise; current academic finance appointment adds governance rigor .

Equity Ownership

Reference DateShares OwnedRight to Acquire (within 60 days)Total Beneficially Owned% of Outstanding
Mar 31, 2025194,095194,095* (less than 1%)
Oct 1, 2025219,095219,095* (less than 1%)
  • Aggregate options held by Clancy (as of Dec 31, 2024): 219,095 options .
  • Anti-hedging and pledging policy: Directors are prohibited from hedging or pledging company stock, aligning with governance best practice .

Governance Assessment

  • Strengths: Independent board chairmanship; independence affirmed by the board; balanced committee structure with independent membership and active meeting cadence; directors excluded from employee option repricing and the 2025 Plan, reducing self-dealing risk; anti-hedging/pledging policy covering directors .
  • Alignment: Clancy’s beneficial ownership is via stock options with no directly owned common shares disclosed; total beneficial ownership <1%, suggesting limited “skin in the game” in direct shares but meaningful option exposure; consider monitoring any future changes in director ownership guidelines or practices .
  • Engagement signals: Historical election support—Clancy received 18,450,957 “For” vs 1,087,467 “Withheld” votes in 2024, indicating strong shareholder backing at that time .
  • RED FLAGS to monitor: Low direct share ownership; significant company overhang and warrant-related dilution dynamics (though directors not participating in repricing/2025 Plan); ensure continued separation from any potential conflicts arising from external biopharma board roles; no Clancy-specific related-party transactions disclosed in available filings .