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Sara Bonstein

Director at Xilio Therapeutics
Board

About Sara M. Bonstein

Independent director at Xilio Therapeutics since August 2021; age 44 as of April 2025. Current CFO of Insmed (since January 2020) with 20+ years in life sciences finance/operations; prior roles include CFO/COO of OncoSec, CFO of Advaxis, and finance roles at Eli Lilly and Johnson & Johnson. Education: B.S. in Finance (The College of New Jersey) and MBA (Rider University). Board has determined she is independent under Nasdaq rules and an “audit committee financial expert.”

Past Roles

OrganizationRoleTenureCommittees/Impact
Insmed, Inc.Chief Financial OfficerJan 2020–presentOversees accounting, FP&A, procurement, IR
OncoSec Medical Inc.Chief Financial Officer & Chief Operating OfficerMay 2018–Jan 2020Led capital markets and licensing transactions
Advaxis, Inc.Chief Financial OfficerFeb 2014–Apr 2018Established financial controls, streamlined operations
Eli Lilly & CompanyFinance rolesNot specifiedProgressive finance responsibilities
Johnson & JohnsonFinance rolesNot specifiedProgressive finance responsibilities

External Roles

OrganizationRoleTenureNotes
scPharmaceuticals Inc.DirectorSince Jul 2020Public company directorship

Board Governance

  • Committee assignments: Audit Committee Chair; members: Sara M. Bonstein (Chair), Aoife Brennan, M.D., Christina Rossi (2025 composition). Audit met five times in 2024.
  • Independence: Board determined in March 2025 that all directors except CEO René Russo are independent (including audit and compensation committees’ Exchange Act criteria).
  • Attendance: Full Board met seven times in 2024; each director attended ≥75% of Board and applicable committee meetings. Six of eight directors attended the 2024 annual meeting.
  • Audit Committee responsibilities include oversight of external auditor, ICFR/disclosure controls, compliance/code of conduct, internal audit, cybersecurity risk, related person transaction approval, and audit report preparation.
  • Compensation Committee (not a member): uses independent consultant Aon; oversight of executive/director compensation and clawback policy; met three times in 2024.
  • Nominating & Corporate Governance Committee (not a member): met two times in 2024.

Fixed Compensation

Director compensation policy (effective April 14, 2025):

ComponentAmount (Cash)
Annual Board retainer (non-employee)$40,000
Chair of Board$70,000
Audit Committee member$7,500
Audit Committee chair$15,000
Compensation Committee member$5,000
Compensation Committee chair$10,000
Nominating & Corporate Governance member$4,000
Nominating & Corporate Governance chair$8,000

Actual director pay:

YearFees Earned (Cash)Option Awards (Grant-date fair value)Total
2023$50,000 $26,774 $76,774
2024$50,000 $19,058 $69,058

Performance Compensation

  • Equity for new non-employee directors: initial stock option to purchase 62,000 shares under the 2021 Plan upon initial election (no performance metrics disclosed for director awards).
  • 2025 Stock Incentive Plan and one-time option repricing proposals exclude non-employee directors (no director participation).

Other Directorships & Interlocks

CompanyRolePotential Interlock/Exposure
scPharmaceuticals Inc.DirectorNo related-party transactions disclosed involving Bonstein
Insmed, Inc.CFONo related-party transactions disclosed involving Bonstein
  • Compensation consultant: Aon Human Capital Solutions retained exclusively by the Compensation Committee; assessed independent, no conflicts.

Expertise & Qualifications

  • Designation: Audit Committee Financial Expert (SEC definition).
  • Core skills: finance leadership, capital markets, licensing, operational streamlining, team-building in biotech.
  • Education: B.S. Finance (TCNJ); MBA (Rider University).

Equity Ownership

  • Beneficial ownership (as of Oct 1, 2025): 104,613 “Right to Acquire” shares via options exercisable within 60 days; no direct common shares disclosed; <1% of outstanding shares (asterisk in table denotes <1%). Total shares outstanding: 51,829,013.
  • Aggregate option holdings (as of Dec 31, 2024): 104,613 options.
HolderShares OwnedRight to Acquire (60 days)Total% Outstanding
Sara M. Bonstein104,613 104,613 * (<1%)
Shares outstanding reference51,829,013 (as of Oct 1, 2025)

Governance Assessment

  • Strengths: Independent director with deep CFO experience; designated audit committee financial expert; audit chair overseeing ICFR, compliance, cybersecurity, and related-party reviews; consistent attendance; no related-party transactions disclosed involving Bonstein.
  • Alignment: Holds options; no outright share ownership disclosed; beneficial ownership <1%—alignment primarily via options rather than common shares.
  • Signals: 2025 proposals to reprice employee options and create 2025 Plan explicitly exclude non-employee directors—mitigates director pay conflicts during repricing.
  • RED FLAGS: None disclosed regarding hedging/pledging, related-party transactions, legal proceedings, or attendance shortfalls for Bonstein. Stock ownership guidelines for directors not disclosed in the proxy.

Note: Director stock ownership guidelines, hedging/pledging policies for directors, and insider trading tables were not disclosed in the cited proxy materials; audit committee retains authority to pre-approve and review related-person transactions.