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Scott Platshon

Director at ZymeworksZymeworks
Board

About Scott Platshon

Scott Platshon, 34, is an independent director of Zymeworks Inc. (ZYME) since February 22, 2024. He is a Partner at EcoR1 Capital (Partner since Dec 2020; with EcoR1 since Oct 2015; previously Principal 2017–2020) and holds a B.S. in Bioengineering from Stanford University. The Board determined all directors except the CEO are independent under Nasdaq rules; Platshon’s current term is part of the class expiring at the 2027 annual meeting. He was appointed under EcoR1’s nomination right agreed in a December 2023 financing (right terminates no later than January 1, 2026).

Past Roles

OrganizationRoleTenureCommittees/Impact
EcoR1 CapitalPartner (prior Principal); with firm since 2015Partner since Dec 2020; Principal Dec 2017–Dec 2020; Analyst at EcoR1 since Oct 2015Investment leadership in biotech
Aquilo PartnersAnalyst (life sciences investment bank)Sep 2014–Sep 2015Healthcare investment banking experience

External Roles

OrganizationRoleTenureNotes
Kumquat Biosciences Inc.Director (prior board observer)Director since Feb 2021; observer since Aug 2019Private biotech; board service
Ajax Therapeutics, Inc.DirectorSince May 2021Board service
Terremoto BiosciencesDirector (former)Oct 2023–Dec 2024Former board service

Board Governance

  • Committee assignments: Not currently listed on standing committees; served on the Compensation Committee from February to November 2025. No chair roles disclosed.
  • Independence: Board determined all directors other than the CEO are independent under Nasdaq rules.
  • Attendance: Board met 5 times in 2024; Platshon attended 5/5 (100%), and each director met the 75% attendance threshold for board/committee meetings served. Compensation Committee held 4 meetings in 2024; Platshon (who joined that committee in 2025) had 0/0 meetings in 2024 by design.
  • Executive sessions: Independent directors meet in executive session at least twice per year per guidelines. Lead Independent Director: Dr. Susan Mahony.
  • Board structure: Staggered board; Platshon’s class term runs to the 2027 annual meeting.

Fixed Compensation

Director policy and Platshon’s actuals:

ItemAmount / OutcomeDetail / VestingSource
Annual Board retainer (Member)$40,000 (2024/2025 policy)Cash; committee fees additional
Committee retainers (selected)Audit Chair $20,000; Audit Member $10,000; Comp Chair $15,000; Comp Member $7,500; Nominating Chair $10,000; Nominating Member $5,000Policy as of Jan 1, 2024; R&D member increased to $7,500 effective Jan 1, 2025
Equity policy (new director initial grant)74,000 options (Dec 2023 policy); reduced to 62,000 options (Dec 2024 update)1/36 monthly vest from grant
Equity policy (annual grant)37,000 options (Dec 2023 policy); reduced to 31,000 options (Dec 2024 update)100% vests at next annual meeting
Post-termination exerciseExtended to 3 years for departing directors (certain cases)Adopted with 2024 program updates
Platshon—2024 Fees Earned (Cash)Waived all cash compensation
Platshon—2024 Option AwardsWaived all equity compensation
Platshon—2024 TotalWaived under non-employee director policy

Platshon waived both cash and equity compensation otherwise payable under the non-employee director compensation policy for 2024.

Performance Compensation

Director equity is time-based (no explicit performance metrics). Structure for context:

Grant TypeGrant Size (policy)VestingTiming
Initial option grant (new director)62,000 options (reduced from 74,000 in Dec 2024)1/36 per monthUpon joining board
Annual option grant (continuing director)31,000 options (reduced from 37,000 in Dec 2024)100% at next annual meetingAt/around annual meeting
Other termsPost-termination exercise windowUp to 3 years for certain director departuresBoard-approved program updates

Platshon received no equity awards in 2024 due to his waiver.

Other Directorships & Interlocks

  • Public company directorships: None disclosed for Platshon; the proxy lists other directors with outside “reporting issuer” boards and does not include Platshon.
  • Compensation Committee interlocks: Disclosure notes which members served in 2024–2025; states none of the committee members (including Platshon during his 2025 service) were officers/employees or had relationships requiring Item 404 disclosure in the last completed fiscal year.
  • Investor interlock: EcoR1 is a significant shareholder; both Oleg Nodelman (EcoR1 manager) and Platshon (EcoR1 Partner) serve on ZYME’s board.

Expertise & Qualifications

  • Education: B.S. in Bioengineering, Stanford University.
  • Technical/industry: Biotech investing and capital markets; prior investment banking analyst (life sciences).
  • Board qualifications cited: Investment and leadership experience; industry knowledge.

Equity Ownership

  • Individual beneficial ownership: No shares or options reported for Platshon as of the record date; director compensation table also shows “nil” options held at Dec 31, 2024.
  • Large holder affiliation: EcoR1 Capital, LLC beneficially owned 22,970,388 shares (30.69% of common stock) as of Nov 3, 2025; footnote notes both Nodelman and Platshon are ZYME directors.
  • Ownership guidelines: Adopted Sept 2025 requiring non-management directors (other than those representing or affiliated with >10% stockholders) to own 10,000 shares by Sept 2028; options/RSUs don’t count. Directors representing/affiliated with >10% holders are excluded from the guideline.
  • Hedging/pledging: Insider Trading Policy prohibits hedging and pledging of Zymeworks securities by directors and other insiders.
HolderShares Beneficially Owned% of Shares Outstanding
Scott Platshon
EcoR1 Capital, LLC (affiliated)22,970,38830.69%

Governance Assessment

Key findings

  • Independence and engagement: Classified independent; strong attendance (5/5 board meetings in 2024). No current committee seat; served on Compensation Committee Feb–Nov 2025.
  • Alignment signals: Waived all director cash and equity compensation for 2024—reduces potential conflicts over director pay and signals investor-aligned posture. Anti-hedging/pledging policy applies.
  • Ownership alignment: No personal holdings disclosed; excluded from new director ownership guideline due to affiliation with >10% holder. However, EcoR1’s 30.69% stake creates significant indirect alignment but also concentrated influence.

Potential conflicts and risk indicators

  • Related-party exposure (monitor): EcoR1 had significant transactions with ZYME, including a Dec 2023 private placement with a nomination right (under which Platshon was appointed) and a June 26, 2025 amendment removing the 19.99% exercise cap on EcoR1’s pre-funded warrants, followed by net exercise to acquire 5,086,521 shares at $0.0001; both Nodelman and Platshon were on the board at the time. Audit Committee oversees related-party transactions per policy; transactions were approved under the formal policy. Nonetheless, ongoing monitoring is warranted due to perceived conflicts.
  • Committee composition optics: Platshon (investor-affiliated) served on the Compensation Committee part of 2025; while independent under Nasdaq rules, investors may scrutinize investor-affiliated directors on comp-setting bodies. Current Compensation Committee members are independent and do not include Platshon.
  • Concentrated shareholder influence: EcoR1’s large position and nomination right (terminating no later than Jan 1, 2026) can raise concerns around board independence over time; explicit independence determinations and related-party review processes mitigate but do not eliminate perception risk.

Shareholder feedback context

  • Say-on-pay: 2024 advisory vote received approximately 93% support, indicating favorable investor sentiment toward executive compensation practices; not directly about director pay but relevant to governance posture.

Fixed Compensation (Detail)

YearCash Retainer ($)Committee Fees ($)Equity ($)Total ($)
2024 (actual)

Note: Platshon waived his entitlement to cash and equity compensation under the non-employee director compensation policy.

Performance Compensation (Detail)

ComponentMetric/TermVestingNotes
Initial director option (policy)74,000 options (Dec 2023); 62,000 options (Dec 2024 update)1/36 monthlyGranted at appointment; time-based only
Annual director option (policy)37,000 options (Dec 2023); 31,000 options (Dec 2024 update)100% at next annual meetingGranted around annual meeting; time-based
Post-termination exerciseUp to 3 years (certain cases)N/ABoard-approved enhancement for departing directors

Other Directorships & Interlocks

CategoryDetail
Current public company boardsNone disclosed for Platshon; other directors with reporting issuer boards listed, but not Platshon
Private/other boardsKumquat Biosciences Inc. (Director); Ajax Therapeutics, Inc. (Director); Terremoto Biosciences (former Director)
Compensation Committee interlocksCommittee members (including Platshon during his 2025 service) were not officers/employees and had no Item 404 relationships in the last fiscal year

Equity Ownership

ItemStatus
Personal holdingsNo shares or options disclosed for Platshon as of Nov 3, 2025; “nil” options at Dec 31, 2024
Large holder affiliationEcoR1 Capital, LLC held 22,970,388 shares (30.69%); both Nodelman and Platshon serve on the Board
Ownership guidelines10,000-share guideline for non-management directors by Sept 2028; excludes those representing/affiliated with >10% holders
Hedging/pledgingProhibited by Insider Trading Policy

Governance Assessment

  • Strengths

    • Independent status and full board attendance in 2024 support board effectiveness.
    • Waiver of director compensation reduces potential pay-related conflicts and aligns with stewardship framing.
    • Formal anti-hedging/anti-pledging and clawback policies strengthen governance.
  • Watch items / RED FLAGS

    • Related-party transactions with EcoR1 (nomination right; warrant cap removal and exercise while EcoR1-affiliated directors were seated). Processes are disclosed and governed by policy, but perceptions of influence and conflicts merit ongoing scrutiny.
    • Investor-affiliated director service on Compensation Committee (part of 2025) can raise optics concerns; current committee composition is independent.

Overall, Platshon brings buy-side expertise and sector knowledge, coupled with strong meeting attendance and a conservative personal pay posture (waiver). The principal governance risk centers on EcoR1’s significant ownership and related transactions (appropriately disclosed and reviewed), requiring continued monitoring by investors for independence in compensation and capital decisions.