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Allostery Investments LP

CIK:0001978599
Hedge Fund
$122M AUM
20 holdings
Stamford, CT, US
Founded:2023
2 employees
Latest filing:Jun 30, 2025

Allostery Investments LP is a hedge fund manager and registered investment adviser headquartered in Stamford, Connecticut. It is incorporated as a Delaware limited partnership. The firm's most recent SEC filings date from 2025. Principals include Christopher Staral. Allostery Investments manages assets predominantly through private investment funds, such as Allostery Master Fund LP (Cayman) and Allostery Fund LP (US).

Investment Strategy

Allostery Investments LP operates as a hedge fund manager, managing portfolios with exposure to a range of public equity and ETF instruments. The firm's recent holdings span biotechnology, healthcare, and technology sectors, using various strategies including long/short equity and derivatives such as calls and puts on indexes and sector-focused ETFs. The firm’s approach is driven by sector and security selection, with a focus on actively trading both US and international equities and employing tactical allocations in growth-oriented sectors such as biotech.

Latest 13F Filing Activity

Allostery Investments LP filed their most recent 13F report on Jun 30, 2025 disclosing 19 equity positions with a total 13F market value of $8M. The fund increased holdings in Rezolute Inc., Akero Therapeutics Inc., Fulcrum Therapeutics Inc. among other positions. Allostery Investments LP reduced exposure to Abivax SA, Kalvista Pharmaceuticals Inc., Centessa Pharmaceuticals PLC among others.

Top Buys
A
AVTXAVALO THERAPEUTICS INC
-$813.3K
V
VRNAVERONA PHARMA PLC
-$557.2K
R
RZLTREZOLUTE INC
+$532.1K
A
AKROAKERO THERAPEUTICS INC
+$472.0K
F
FULCFULCRUM THERAPEUTICS INC
+$277.6K
Top Sells
A
ABVXABIVAX SA
-$5.6M
K
KALVKALVISTA PHARMACEUTICALS INC
-$4.8M
C
CNTACENTESSA PHARMACEUTICALS PLC
-$4.8M
M
MRUSMERUS N V
-$4.8M
E
EOLSEVOLUS INC
-$4.4M

Top Holdings

A
ABVXABIVAX SA
+16.3%$1.3M
A
AKROAKERO THERAPEUTICS INC
+15.3%$1.2M
A
AMLXAMYLYX PHARMACEUTICALS INC
+9.8%$770.0K
C
CNTACENTESSA PHARMACEUTICALS PLC
+8.8%$689.9K
E
EOLSEVOLUS INC
+7.0%$552.6K

Equity Positions (19)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
ABIVAX SA16.31%$1.3M167,350$6.83$7.65-$5.6M
AKERO THERAPEUTICS INC15.29%$1.2M22,500$43.06$53.36+$472.0K
AMYLYX PHARMACEUTICALS INC9.81%$770.0K120,119$3.54$6.41-$172.0K
CENTESSA PHARMACEUTICALS PLC8.79%$689.9K52,500$16.14$13.14-$4.8M
EVOLUS INC7.04%$552.6K60,000$11.04$9.21-$4.4M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+93.0%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+6.1%