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TRV GP IV, LLC

CIK:0001688325
Hedge Fund
$93M AUM
3 holdings
Boston, MA, United States
Founded:2016
10 employees
Latest filing:Jun 30, 2025

TRV GP IV, LLC is a U.S.-based investment firm headquartered in Boston, Massachusetts. The firm primarily manages hedge fund portfolios and is known for managing concentrated positions in biotechnology and therapeutics companies. Founded in 2016, TRV GP IV, LLC operates with a lean team structure, as is common in specialized hedge funds, though the precise employee count is not publicly disclosed. It serves institutional investors and other qualified clients, pursuing investment opportunities largely in the healthcare and biotechnology sectors.

Investment Strategy

TRV GP IV, LLC focuses its investment strategy primarily on equity investments in innovative healthcare and biotechnology companies. The fund takes highly concentrated positions, as evidenced by its small number of significant holdings such as Tango Therapeutics, Pliant Therapeutics, and Fulcrum Therapeutics. This approach seeks to generate outsized returns by backing companies with high growth potential and industry-disrupting advances, often holding these positions over extended periods. TRV GP IV leverages deep sector expertise to identify and support companies at the forefront of therapeutic innovation, with a strong emphasis on long-term value creation.

Top Buys
T
TNGXTANGO THERAPEUTICS, INC.
+$63.2M
M
MAZEMAZE THERAPEUTICS, INC.
+$7.7M
P
PLRXPLIANT THERAPEUTICS, INC.
-$405.2K
Top Sells
T
TNGXTANGO THERAPEUTICS, INC.
+$63.2M
M
MAZEMAZE THERAPEUTICS, INC.
+$7.7M
P
PLRXPLIANT THERAPEUTICS, INC.
-$405.2K

Top Holdings

T
TNGXTANGO THERAPEUTICS, INC.
+52.9%$86.3M
M
MAZEMAZE THERAPEUTICS, INC.
+45.6%$74.5M
P
PLRXPLIANT THERAPEUTICS, INC.
+1.5%$2.5M

Equity Positions (3)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
T
TNGX
TANGO THERAPEUTICS, INC.52.85%$86.3M16,859,075$12.93$5.12+$63.2M
M
MAZE
MAZE THERAPEUTICS, INC.45.63%$74.5M6,073,958$11.01$12.27+$7.7M
P
PLRX
PLIANT THERAPEUTICS, INC.1.51%$2.5M2,132,867$32.46$1.16-$405.2K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+54.4%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+45.6%