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Bios Capital Management, LP

CIK:0001813845
Investment Adviser
$272M AUM
6 holdings
Fort Worth, TX, US
Founded:2019
8 employees
Latest filing:Jun 30, 2025

BIOS Capital Management, LP is an SEC-registered investment adviser headquartered in Fort Worth, Texas. The firm, founded in 2019, employs around 8 staff, primarily investment professionals. BIOS focuses on investments in the healthcare and biotechnology sector, managing capital for institutional investors and high-net-worth individuals, and is known for building concentrated long-term positions in emerging therapeutics and life science companies.

Investment Strategy

BIOS Capital Management adopts a science-driven, long-term investment approach focused on identifying and partnering with innovative life sciences and biotechnology companies. Their strategy emphasizes concentrated holdings in early-stage therapeutics, leveraging deep sector expertise to originate and manage investments in companies developing novel platforms, drugs, or technologies. The firm maintains a hands-on, fundamental research process and prefers higher-conviction positions in the healthcare sector.

Latest 13F Filing Activity

Bios Capital Management, LP filed their most recent 13F report on Jun 30, 2025 disclosing 5 equity positions with a total 13F market value of $73M. The fund increased holdings in Rein Therapeutics Inc., Cognition Therapeutics Inc., In8bio Inc. among other positions. Bios Capital Management, LP reduced exposure to Actuate Therapeutics Inc., Lantern Pharma Inc., In8bio Inc. among others.

Top Buys
A
ACTUACTUATE THERAPEUTICS INC
-$6.1M
L
LTRNLANTERN PHARMA INC
-$875.3K
I
INABIN8BIO INC
-$828.5K
C
CGTXCOGNITION THERAPEUTICS INC
-$664.8K
R
RNTXREIN THERAPEUTICS INC
-$625.6K
Top Sells
A
ACTUACTUATE THERAPEUTICS INC
-$6.1M
L
LTRNLANTERN PHARMA INC
-$875.3K
I
INABIN8BIO INC
-$828.5K
C
CGTXCOGNITION THERAPEUTICS INC
-$664.8K
R
RNTXREIN THERAPEUTICS INC
-$625.6K

Top Holdings

A
ACTUACTUATE THERAPEUTICS INC
+83.9%$60.9M
L
LTRNLANTERN PHARMA INC
+4.7%$3.4M
R
RNTXREIN THERAPEUTICS INC
+3.3%$2.4M
C
CGTXCOGNITION THERAPEUTICS INC
+2.6%$1.9M
I
INABIN8BIO INC
+0.8%$599.1K

Equity Positions (5)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
ACTUATE THERAPEUTICS INC83.89%$60.9M9,965,079$7.95$6.11-$6.1M
LANTERN PHARMA INC4.68%$3.4M1,075,952$3.19$3.16-$875.3K
REIN THERAPEUTICS INC3.26%$2.4M1,690,751$2.30$1.40-$625.6K
COGNITION THERAPEUTICS INC2.56%$1.9M6,000,000$0.70$0.31-$664.8K
IN8BIO INC0.83%$599.1K286,664$7.72$2.09-$828.5K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+82.8%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+9.8%