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Propel Bio Management, LLC

CIK:0001969764
Investment Adviser
$150M AUM
16 holdings
Los Angeles, CA, United States
Founded:2022
6 employees
Latest filing:Jun 30, 2025

PROPEL BIO MANAGEMENT, LLC is a Delaware limited liability company headquartered in Los Angeles, California. Founded in 2022, it is owned by Leen Kawas and is focused on supporting life sciences and biotechnology companies. The firm acts as an investment adviser and typically manages a small team (between 6 and 7 employees) with significant investment and scientific expertise. Propel Bio Management, LLC serves entrepreneurial founders in the biotech and life science sectors, advancing groundbreaking technologies and therapies to improve human health.

Investment Strategy

Propel Bio Management, LLC drives its investment strategy by leveraging deep scientific and business expertise to invest in entrepreneurial life sciences companies. The firm focuses on companies developing disruptive therapies and technologies with the goal of advancing human health. Propel Bio supports its portfolio companies with an ecosystem of experts spanning life science industry, finance, and investment disciplines, aiming to help founders fulfill urgent missions in healthcare innovation. Their approach emphasizes purposeful and efficient advancement of science, supporting founders from early development to commercialization.

Top Buys
A
ACHVACHIEVE LIFE SCIENCES INC
+$7.4M
A
AKROAKERO THERAPEUTICS INC
+$2.9M
0
0H7R.LABEONA THERAPEUTICS INC
+$2.6M
M
MISTMILESTONE PHARMACEUTICALS
+$2.3M
P
PHATPHATHOM PHARMACEUTICALS I
+$1.7M
Top Sells
M
MDGLMADRIGAL PHARMACEUTICALS
-$9.9M
R
RNAAVIDITY BIOSCIENCES INC
-$5.3M
P
PAGPPLAINS GP HOLDINGS LP-CL
-$2.5M
S
SNDXSYNDAX PHARMACEUTICALS IN
-$2.3M
A
APLTAPPLIED THERAPEUTICS INC
-$2.0M

Top Holdings

P
PAGPPLAINS GP HOLDINGS LP-CL
+30.0%$24.7M
A
ACHVACHIEVE LIFE SCIENCES INC
+16.9%$13.9M
A
AKROAKERO THERAPEUTICS INC
+14.8%$12.2M
P
PHATPHATHOM PHARMACEUTICALS I
+10.7%$8.9M
0
0H7R.LABEONA THERAPEUTICS INC
+6.7%$5.5M

Equity Positions (12)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
P
PAGP
PLAINS GP HOLDINGS LP-CL30.01%$24.7M1,272,360$19.03$19.43-$2.5M
A
ACHV
ACHIEVE LIFE SCIENCES INC16.88%$13.9M6,153,091$3.18$2.26+$7.4M
A
AKRO
AKERO THERAPEUTICS INC14.82%$12.2M228,884$24.08$53.36+$2.9M
P
PHAT
PHATHOM PHARMACEUTICALS I10.74%$8.9M922,927$9.21$9.59+$1.7M
0
0H7R.L
ABEONA THERAPEUTICS INC6.71%$5.5M974,022$4.69$5.66+$2.6M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+37.4%
PIPE LINES (NO NATURAL GAS)
+30.0%
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
+16.9%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+4.2%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+3.7%