Question · Q3 2025
David Reisinger inquired about Johnson & Johnson's strategy for positioning icatrekibart relative to Tremfya, given their similar indications.
Answer
EVP, Worldwide Chairman, Innovative Medicine Jennifer Taubert expressed excitement for icatrekibart as a potential $5 billion+ brand, expected to set a new standard in plaque psoriasis with its combination of complete skin clearance, favorable safety, and oral pill simplicity. She noted its study against other orals and head-to-head versus Stelara, and the significant market expansion opportunity. She anticipates distinct positioning for both icatrekibart and Tremfya, allowing continued significant growth for both assets. EVP, Innovative Medicine Research and Development John Reed mentioned upcoming publications in the New England Journal of Medicine and The Lancet for icatrekibart data, including a head-to-head study against a leading TYK2 inhibitor.