Elemer Piros's questions to Compass Pathways PLC (CMPS) leadership • Q3 2024
Question
Elemer Piros of Rodman & Renshaw asked about the specifics of the retreatment protocol in the trials, including how relapse is defined and whether patients who resume taking antidepressants must undergo another washout period before retreatment with COMP360.
Answer
Guy Goodwin (Executive) clarified the retreatment criteria. He explained that patients who go back on antidepressants can remain on them during retreatment, which provides useful co-administration data. He stated that the criteria for retreatment, which is based on a MADRS score threshold, is the same for patients who did not respond initially and for those who relapsed after responding.